Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling T Ida, T Sawa, H Ihara, Y Tsuchiya, Y Watanabe, Y Kumagai, M Suematsu, ... Proceedings of the National Academy of Sciences 111 (21), 7606-7611, 2014 | 873 | 2014 |
Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/. bul. NO (nitric oxide) through a radical reaction T Akaike, M Yoshida, Y Miyamoto, K Sato, M Kohno, K Sasamoto, ... Biochemistry 32 (3), 827-832, 1993 | 680 | 1993 |
Nitric oxide and oxygen radicals in infection, inflammation, and cancer H Maeda, T Akaike BIOCHEMISTRY C/C OF BIOKHIMIIA 63, 854-865, 1998 | 659 | 1998 |
Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. T Akaike, Y Noguchi, S Ijiri, K Setoguchi, M Suga, YM Zheng, ... Proceedings of the National Academy of Sciences 93 (6), 2448-2453, 1996 | 623 | 1996 |
Early phase tumor accumulation of macromolecules: a great difference in clearance rate between tumor and normal tissues Y Noguchi, J Wu, R Duncan, J Strohalm, K Ulbrich, T Akaike, H Maeda Japanese Journal of Cancer Research 89 (3), 307-314, 1998 | 613 | 1998 |
Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation T Okamoto, T Akaike, T Sawa, Y Miyamoto, A Van der Vliet, H Maeda Journal of Biological Chemistry 276 (31), 29596-29602, 2001 | 547 | 2001 |
Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD T Oda, T Akaike, T Hamamoto, F Suzuki, T Hirano, H Maeda Science 244 (4907), 974-976, 1989 | 540 | 1989 |
Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor-promoter effect of vegetables T Sawa, M Nakao, T Akaike, K Ono, H Maeda Journal of Agricultural and Food Chemistry 47 (2), 397-402, 1999 | 493 | 1999 |
Nitric oxide and virus infection T Akaike, H Maeda Immunology 101 (3), 300-308, 2000 | 477 | 2000 |
Keap1 degradation by autophagy for the maintenance of redox homeostasis K Taguchi, N Fujikawa, M Komatsu, T Ishii, M Unno, T Akaike, ... Proceedings of the National Academy of Sciences 109 (34), 13561-13566, 2012 | 467 | 2012 |
Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics T Akaike, T Ida, FY Wei, M Nishida, Y Kumagai, MM Alam, H Ihara, ... Nature communications 8 (1), 1177, 2017 | 448 | 2017 |
Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis DC Hooper, O Bagasra, JC Marini, A Zborek, ST Ohnishi, R Kean, ... Proceedings of the National Academy of Sciences 94 (6), 2528-2533, 1997 | 429 | 1997 |
Dependence on O2-generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. T Akaike, M Ando, T Oda, T Doi, S Ijiri, S Araki, H Maeda The Journal of clinical investigation 85 (3), 739-745, 1990 | 419 | 1990 |
Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility K Ono, T Akaike, T Sawa, Y Kumagai, DA Wink, DJ Tantillo, AJ Hobbs, ... Free Radical Biology and Medicine 77, 82-94, 2014 | 399 | 2014 |
AUTACs: cargo-specific degraders using selective autophagy D Takahashi, J Moriyama, T Nakamura, E Miki, E Takahashi, A Sato, ... Molecular cell 76 (5), 797-810. e10, 2019 | 379 | 2019 |
Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration M Nishida, T Sawa, N Kitajima, K Ono, H Inoue, H Ihara, H Motohashi, ... Nature chemical biology 8 (8), 714-724, 2012 | 338 | 2012 |
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias M Suga, K Iyonaga, T Okamoto, Y Gushima, H Miyakawa, T Akaike, ... American journal of respiratory and critical care medicine 162 (5), 1949-1956, 2000 | 318 | 2000 |
Protein S-guanylation by the biological signal 8-nitroguanosine 3′, 5′-cyclic monophosphate T Sawa, MH Zaki, T Okamoto, T Akuta, Y Tokutomi, S Kim-Mitsuyama, ... Nature chemical biology 3 (11), 727-735, 2007 | 303 | 2007 |
In Vivo Antitumor Activity of Pegylated Zinc Protoporphyrin: Targeted Inhibition of Heme Oxygenase in Solid Tumor J Fang, T Sawa, T Akaike, T Akuta, SK Sahoo, G Khaled, A Hamada, ... Cancer research 63 (13), 3567-3574, 2003 | 299 | 2003 |
Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide T Okamoto, T Akaike, T Nagano, S Miyajima, M Suga, M Ando, K Ichimori, ... Archives of Biochemistry and Biophysics 342 (2), 261-274, 1997 | 297 | 1997 |