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Luke Whiley
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Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease
L Whiley, A Sen, J Heaton, P Proitsi, D García-Gómez, R Leung, N Smith, ...
Neurobiology of aging 35 (2), 271-278, 2014
3172014
Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis
P Proitsi, M Kim, L Whiley, A Simmons, M Sattlecker, L Velayudhan, ...
Alzheimer's & Dementia 13 (2), 140-151, 2017
2002017
Integrative modeling of quantitative plasma lipoprotein, metabolic, and amino acid data reveals a multiorgan pathological signature of SARS-CoV-2 infection
T Kimhofer, S Lodge, L Whiley, N Gray, RL Loo, NG Lawler, P Nitschke, ...
Journal of proteome research 19 (11), 4442-4454, 2020
1692020
Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease
P Proitsi, M Kim, L Whiley, M Pritchard, R Leung, H Soininen, ...
Translational psychiatry 5 (1), e494-e494, 2015
1472015
In-vial dual extraction for direct LC-MS analysis of plasma for comprehensive and highly reproducible metabolic fingerprinting.
L Whiley, J Godzien, FJ Ruperez, C Legido-Quigley, C Barbas
Analytical chemistry 84 (14), 5992-5999, 2012
1322012
XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules
X Domingo-Almenara, JR Montenegro-Burke, J Ivanisevic, A Thomas, ...
Nature methods 15 (9), 681-684, 2018
1282018
Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor
GZ Wei, KA Martin, PY Xing, R Agrawal, L Whiley, TK Wood, S Hejndorf, ...
Proceedings of the National Academy of Sciences 118 (27), e2021091118, 2021
1242021
Incomplete systemic recovery and metabolic phenoreversion in post-acute-phase nonhospitalized COVID-19 patients: implications for assessment of post-acute COVID-19 syndrome
E Holmes, J Wist, R Masuda, S Lodge, P Nitschke, T Kimhofer, RL Loo, ...
Journal of proteome research 20 (6), 3315-3329, 2021
1132021
Systemic perturbations in amine and kynurenine metabolism associated with acute SARS-CoV-2 infection and inflammatory cytokine responses
NG Lawler, N Gray, T Kimhofer, B Boughton, M Gay, R Yang, AC Morillon, ...
Journal of Proteome Research 20 (5), 2796-2811, 2021
1072021
Ultrahigh-performance liquid chromatography tandem mass spectrometry with electrospray ionization quantification of tryptophan metabolites and markers of gut health in serum …
L Whiley, LC Nye, I Grant, N Andreas, KE Chappell, MH Sarafian, R Misra, ...
Analytical chemistry 91 (8), 5207-5216, 2019
952019
Association between plasma ceramides and phosphatidylcholines and hippocampal brain volume in late onset Alzheimer’s disease
M Kim, A Nevado-Holgado, L Whiley, SG Snowden, H Soininen, ...
Journal of Alzheimer's Disease 60 (3), 809-817, 2017
882017
Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with …
L Whiley, KE Chappell, E D’hondt, MR Lewis, B Jiménez, SG Snowden, ...
Alzheimer's research & therapy 13, 1-18, 2021
772021
Quantitative in-vitro diagnostic NMR spectroscopy for lipoprotein and metabolite measurements in plasma and serum: recommendations for analytical artifact minimization with …
RL Loo, S Lodge, T Kimhofer, SH Bong, S Begum, L Whiley, N Gray, ...
Journal of Proteome Research 19 (11), 4428-4441, 2020
442020
Diagnostic potential of the plasma lipidome in infectious disease: application to acute SARS-CoV-2 infection
N Gray, NG Lawler, AX Zeng, M Ryan, SH Bong, BA Boughton, ...
Metabolites 11 (7), 467, 2021
382021
In-vial dual extraction liquid chromatography coupled to mass spectrometry applied to streptozotocin-treated diabetic rats. Tips and pitfalls of the method
J Godzien, M Ciborowski, L Whiley, C Legido-Quigley, FJ Ruperez, ...
Journal of Chromatography A 1304, 52-60, 2013
372013
Urinary metabolic phenotyping for Alzheimer’s disease
N Kurbatova, M Garg, L Whiley, E Chekmeneva, B Jiménez, ...
Scientific reports 10 (1), 21745, 2020
352020
Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig
ME Price, CJ Docx, H Rice, SJ Fairhall, SJC Poole, M Bird, L Whiley, ...
Toxicology letters 244, 154-160, 2016
342016
A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS
N Gray, NG Lawler, R Yang, AC Morillon, MCL Gay, SH Bong, E Holmes, ...
Talanta 223, 121872, 2021
292021
Current strategies in the discovery of small-molecule biomarkers for Alzheimer’s disease
L Whiley, C Legido-Quigley
Bioanalysis 3 (10), 1121-1142, 2011
282011
A patient-centric modeling framework captures recovery from SARS-CoV-2 infection
H Ruffieux, AL Hanson, S Lodge, NG Lawler, L Whiley, N Gray, TH Nolan, ...
Nature immunology 24 (2), 349-358, 2023
252023
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