Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease L Whiley, A Sen, J Heaton, P Proitsi, D García-Gómez, R Leung, N Smith, ... Neurobiology of aging 35 (2), 271-278, 2014 | 317 | 2014 |
Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis P Proitsi, M Kim, L Whiley, A Simmons, M Sattlecker, L Velayudhan, ... Alzheimer's & Dementia 13 (2), 140-151, 2017 | 200 | 2017 |
Integrative modeling of quantitative plasma lipoprotein, metabolic, and amino acid data reveals a multiorgan pathological signature of SARS-CoV-2 infection T Kimhofer, S Lodge, L Whiley, N Gray, RL Loo, NG Lawler, P Nitschke, ... Journal of proteome research 19 (11), 4442-4454, 2020 | 169 | 2020 |
Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease P Proitsi, M Kim, L Whiley, M Pritchard, R Leung, H Soininen, ... Translational psychiatry 5 (1), e494-e494, 2015 | 147 | 2015 |
In-vial dual extraction for direct LC-MS analysis of plasma for comprehensive and highly reproducible metabolic fingerprinting. L Whiley, J Godzien, FJ Ruperez, C Legido-Quigley, C Barbas Analytical chemistry 84 (14), 5992-5999, 2012 | 132 | 2012 |
XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules X Domingo-Almenara, JR Montenegro-Burke, J Ivanisevic, A Thomas, ... Nature methods 15 (9), 681-684, 2018 | 128 | 2018 |
Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor GZ Wei, KA Martin, PY Xing, R Agrawal, L Whiley, TK Wood, S Hejndorf, ... Proceedings of the National Academy of Sciences 118 (27), e2021091118, 2021 | 124 | 2021 |
Incomplete systemic recovery and metabolic phenoreversion in post-acute-phase nonhospitalized COVID-19 patients: implications for assessment of post-acute COVID-19 syndrome E Holmes, J Wist, R Masuda, S Lodge, P Nitschke, T Kimhofer, RL Loo, ... Journal of proteome research 20 (6), 3315-3329, 2021 | 113 | 2021 |
Systemic perturbations in amine and kynurenine metabolism associated with acute SARS-CoV-2 infection and inflammatory cytokine responses NG Lawler, N Gray, T Kimhofer, B Boughton, M Gay, R Yang, AC Morillon, ... Journal of Proteome Research 20 (5), 2796-2811, 2021 | 107 | 2021 |
Ultrahigh-performance liquid chromatography tandem mass spectrometry with electrospray ionization quantification of tryptophan metabolites and markers of gut health in serum … L Whiley, LC Nye, I Grant, N Andreas, KE Chappell, MH Sarafian, R Misra, ... Analytical chemistry 91 (8), 5207-5216, 2019 | 95 | 2019 |
Association between plasma ceramides and phosphatidylcholines and hippocampal brain volume in late onset Alzheimer’s disease M Kim, A Nevado-Holgado, L Whiley, SG Snowden, H Soininen, ... Journal of Alzheimer's Disease 60 (3), 809-817, 2017 | 88 | 2017 |
Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with … L Whiley, KE Chappell, E D’hondt, MR Lewis, B Jiménez, SG Snowden, ... Alzheimer's research & therapy 13, 1-18, 2021 | 77 | 2021 |
Quantitative in-vitro diagnostic NMR spectroscopy for lipoprotein and metabolite measurements in plasma and serum: recommendations for analytical artifact minimization with … RL Loo, S Lodge, T Kimhofer, SH Bong, S Begum, L Whiley, N Gray, ... Journal of Proteome Research 19 (11), 4428-4441, 2020 | 44 | 2020 |
Diagnostic potential of the plasma lipidome in infectious disease: application to acute SARS-CoV-2 infection N Gray, NG Lawler, AX Zeng, M Ryan, SH Bong, BA Boughton, ... Metabolites 11 (7), 467, 2021 | 38 | 2021 |
In-vial dual extraction liquid chromatography coupled to mass spectrometry applied to streptozotocin-treated diabetic rats. Tips and pitfalls of the method J Godzien, M Ciborowski, L Whiley, C Legido-Quigley, FJ Ruperez, ... Journal of Chromatography A 1304, 52-60, 2013 | 37 | 2013 |
Urinary metabolic phenotyping for Alzheimer’s disease N Kurbatova, M Garg, L Whiley, E Chekmeneva, B Jiménez, ... Scientific reports 10 (1), 21745, 2020 | 35 | 2020 |
Pharmacokinetic profile and quantitation of protection against soman poisoning by the antinicotinic compound MB327 in the guinea-pig ME Price, CJ Docx, H Rice, SJ Fairhall, SJC Poole, M Bird, L Whiley, ... Toxicology letters 244, 154-160, 2016 | 34 | 2016 |
A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS N Gray, NG Lawler, R Yang, AC Morillon, MCL Gay, SH Bong, E Holmes, ... Talanta 223, 121872, 2021 | 29 | 2021 |
Current strategies in the discovery of small-molecule biomarkers for Alzheimer’s disease L Whiley, C Legido-Quigley Bioanalysis 3 (10), 1121-1142, 2011 | 28 | 2011 |
A patient-centric modeling framework captures recovery from SARS-CoV-2 infection H Ruffieux, AL Hanson, S Lodge, NG Lawler, L Whiley, N Gray, TH Nolan, ... Nature immunology 24 (2), 349-358, 2023 | 25 | 2023 |