David B Hill
David B Hill
Joint Department of Biomedical Engineering, The Marsico Lung Institute, UNC CH
Verified email at - Homepage
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A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ...
Science 337 (6097), 937-941, 2012
A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms
H Matsui, VE Wagner, DB Hill, UE Schwab, TD Rogers, B Button, ...
Proceedings of the National Academy of Sciences 103 (48), 18131-18136, 2006
A biophysical basis for mucus solids concentration as a candidate biomarker for airways disease
DB Hill, PA Vasquez, J Mellnik, SA McKinley, A Vose, F Mu, ...
PloS one 9 (2), e87681, 2014
Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice
LA Hancock, CE Hennessy, GM Solomon, E Dobrinskikh, A Estrella, ...
Nature communications 9 (1), 5363, 2018
Fast vesicle transport in PC12 neurites: velocities and forces
DB Hill, MJ Plaza, K Bonin, G Holzwarth
European Biophysics Journal 33, 623-632, 2004
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis
CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ...
Science translational medicine 11 (486), eaav3488, 2019
Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH
DB Hill, RF Long, WJ Kissner, E Atieh, IC Garbarine, MR Markovetz, ...
European Respiratory Journal 52 (6), 2018
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells
JC Seagrave, HH Albrecht, DB Hill, DF Rogers, G Solomon
Respiratory research 13 (1), 1-10, 2012
An improved inhaled mucolytic to treat airway muco-obstructive diseases
C Ehre, ZL Rushton, B Wang, LN Hothem, CB Morrison, NC Fontana, ...
American journal of respiratory and critical care medicine 199 (2), 171-180, 2019
Monitoring airway mucus flow and ciliary activity with optical coherence tomography
AL Oldenburg, RK Chhetri, DB Hill, B Button
Biomedical optics express 3 (9), 1978-1992, 2012
Force generation and dynamics of individual cilia under external loading
DB Hill, V Swaminathan, A Estes, J Cribb, ET O'Brien, CW Davis, ...
Biophysical journal 98 (1), 57-66, 2010
Airway mucus hyperconcentration in non–cystic fibrosis bronchiectasis
KA Ramsey, ACH Chen, G Radicioni, R Lourie, M Martin, A Broomfield, ...
American journal of respiratory and critical care medicine 201 (6), 661-670, 2020
Physiology and pathophysiology of human airway mucus
DB Hill, B Button, M Rubinstein, RC Boucher
Physiological Reviews 102 (4), 1757-1836, 2022
Establishment of respiratory air–liquid interface cultures and their use in studying mucin production, secretion, and function
DB Hill, B Button
Mucins: Methods and Protocols, 245-258, 2012
Model comparison and assessment for single particle tracking in biological fluids
M Lysy, NS Pillai, DB Hill, MG Forest, JWR Mellnik, PA Vasquez, ...
Journal of the American Statistical Association 111 (516), 1413-1426, 2016
Disruption and eradication of P. aeruginosa biofilms using nitric oxide-releasing chitosan oligosaccharides
KP Reighard, DB Hill, GA Dixon, BV Worley, MH Schoenfisch
Biofouling 31 (9-10), 775-787, 2015
Probing biological nanotopology via diffusion of weakly constrained plasmonic nanorods with optical coherence tomography
RK Chhetri, RL Blackmon, WC Wu, DB Hill, B Button, ...
Proceedings of the National Academy of Sciences 111 (41), E4289-E4297, 2014
Pulmonary fluid flow challenges for experimental and mathematical modeling
R Levy, DB Hill, MG Forest, JB Grotberg
American Zoologist 54 (6), 985-1000, 2014
Modeling and simulation of mucus flow in human bronchial epithelial cell cultures–Part I: Idealized axisymmetric swirling flow
PA Vasquez, Y Jin, E Palmer, D Hill, MG Forest
PLoS Computational Biology 12 (8), e1004872, 2016
Forces required of kinesin during processive transport through cytoplasm
G Holzwarth, K Bonin, DB Hill
Biophysical journal 82 (4), 1784-1790, 2002
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