| Mammalian heme peroxidases: from molecular mechanisms to health implications MJ Davies, CL Hawkins, DI Pattison, MD Rees Antioxidants & redox signaling 10 (7), 1199-1234, 2008 | 653 | 2008 |
| Oxidative damage to extracellular matrix and its role in human pathologies MD Rees, EC Kennett, JM Whitelock, MJ Davies Free Radical Biology and Medicine 44 (12), 1973-2001, 2008 | 280 | 2008 |
| Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation FC Meotti, GNL Jameson, R Turner, DT Harwood, S Stockwell, MD Rees, ... Journal of Biological Chemistry 286 (15), 12901-12911, 2011 | 161 | 2011 |
| Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates MD Rees, CL Hawkins, MJ Davies Biochemical Journal 381 (1), 175-184, 2004 | 142 | 2004 |
| Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan CY Chuang, MS Lord, J Melrose, MD Rees, SM Knox, C Freeman, ... Biochemistry 49 (26), 5524-5532, 2010 | 136 | 2010 |
| Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer … MD Rees, CL Hawkins, MJ Davies Journal of the American Chemical Society 125 (45), 13719-13733, 2003 | 119 | 2003 |
| Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides MD Rees, SE Bottle, KE Fairfull-Smith, E Malle, JM Whitelock, MJ Davies Biochemical Journal 421 (1), 79-86, 2009 | 99 | 2009 |
| Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations M Koelsch, R Mallak, GG Graham, T Kajer, MK Milligan, LQ Nguyen, ... Biochemical pharmacology 79 (8), 1156-1164, 2010 | 75 | 2010 |
| Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan MD Rees, JM Whitelock, E Malle, CY Chuang, RV Iozzo, A Nilasaroya, ... Matrix biology 29 (1), 63-73, 2010 | 75 | 2010 |
| Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation MD Rees, DI Pattison, MJ Davies Biochemical Journal 391 (Pt 1), 125, 2005 | 69 | 2005 |
| Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins CL Hawkins, MD Rees, MJ Davies FEBS letters 510 (1-2), 41-44, 2002 | 63 | 2002 |
| Human indoleamine 2, 3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide M Freewan, MD Rees, TSS Plaza, E Glaros, YJ Lim, XS Wang, ... Journal of Biological Chemistry 288 (3), 1548-1567, 2013 | 62 | 2013 |
| Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains EC Kennett, MD Rees, E Malle, A Hammer, JM Whitelock, MJ Davies Free Radical Biology and Medicine 49 (2), 282-293, 2010 | 57 | 2010 |
| Degradation of extracellular matrix and its components by hypobromous acid MD Rees, TN McNiven, MJ Davies Biochemical Journal 401 (2), 587-596, 2007 | 53 | 2007 |
| Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives MD Rees, MJ Davies Journal of the American Chemical Society 128 (9), 3085-3097, 2006 | 53 | 2006 |
| Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells MD Rees, L Dang, T Thai, DM Owen, E Malle, SR Thomas Free Radical Biology and Medicine, 2012 | 50 | 2012 |
| Myeloperoxidase: A versatile mediator of endothelial dysfunction and therapeutic target during cardiovascular disease SL Maiocchi, J Ku, T Thai, E Chan, MD Rees, SR Thomas Pharmacology & therapeutics 221, 107711, 2021 | 47 | 2021 |
| Regulation of the nitric oxide oxidase activity of myeloperoxidase by pharmacological agents SL Maiocchi, JC Morris, MD Rees, SR Thomas Biochemical Pharmacology 135, 90-115, 2017 | 37 | 2017 |
| Mechanism and regulation of peroxidase-catalyzed nitric oxide consumption in physiological fluids: critical protective actions of ascorbate and thiocyanate MD Rees, SL Maiocchi, AJ Kettle, SR Thomas Free Radical Biology and Medicine 72, 91-103, 2014 | 25 | 2014 |
| Recombinant heparan sulfate for use in tissue engineering applications J Whitelock, JL Ma, N Davies, N Nielsen, C Chuang, M Rees, RV Iozzo, ... Journal of Chemical Technology & Biotechnology: International Research in …, 2008 | 17 | 2008 |
David I PattisonDept of Plant and Environmental Science, University of CopenhagenVerified email at plen.ku.dk
