| NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis SA Hirota, J Ng, A Lueng, M Khajah, K Parhar, Y Li, V Lam, MS Potentier, ... Inflammatory bowel diseases 17 (6), 1359-1372, 2011 | 496 | 2011 |
| Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis BD Gulbransen, M Bashashati, SA Hirota, X Gui, JA Roberts, ... Nature medicine 18 (4), 600-604, 2012 | 443 | 2012 |
| Targeting aquaporin-4 subcellular localization to treat central nervous system edema P Kitchen, MM Salman, AM Halsey, C Clarke-Bland, JA MacDonald, ... Cell 181 (4), 784-799. e19, 2020 | 373 | 2020 |
| Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides AA Wooldridge, JA MacDonald, F Erdodi, C Ma, MA Borman, ... Journal of Biological Chemistry 279 (33), 34496-34504, 2004 | 304 | 2004 |
| NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations L Mortimer, F Moreau, JA MacDonald, K Chadee Nature immunology 17 (10), 1176-1186, 2016 | 277 | 2016 |
| The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1δ ME Grassie, LD Moffat, MP Walsh, JA MacDonald Archives of biochemistry and biophysics 510 (2), 147-159, 2011 | 268 | 2011 |
| Identification of the endogenous smooth muscle myosin phosphatase-associated kinase JA MacDonald, MA Borman, A Murányi, AV Somlyo, DJ Hartshorne, ... Proceedings of the National Academy of Sciences 98 (5), 2419-2424, 2001 | 268 | 2001 |
| Clostridium difficile toxin–induced inflammation and intestinal injury are mediated by the inflammasome J Ng, SA Hirota, O Gross, Y Li, A Ulke–Lemee, MS Potentier, LP Schenck, ... Gastroenterology 139 (2), 542-552. e3, 2010 | 263 | 2010 |
| Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase A Murányi, JA MacDonald, JT Deng, DP Wilson, TAJ Haystead, MP Walsh, ... Biochemical Journal 366 (1), 211-216, 2002 | 231 | 2002 |
| The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ... Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012 | 216 | 2012 |
| The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin‐1β NA Bracey, PL Beck, DA Muruve, SA Hirota, J Guo, H Jabagi, JR Wright Jr, ... Experimental physiology 98 (2), 462-472, 2013 | 201 | 2013 |
| Regulation of ground squirrel Na+ K+-ATPase activity by reversible phosphorylation during hibernation JA MacDonald, KB Storey Biochemical and biophysical research communications 254 (2), 424-429, 1999 | 184 | 1999 |
| C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats JC Jones, HP Phatnani, TA Haystead, JA MacDonald, SM Alam, ... Journal of Biological Chemistry 279 (24), 24957-24964, 2004 | 170 | 2004 |
| Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase JA MacDonald, M Eto, MA Borman, DL Brautigan, TAJ Haystead FEBS letters 493 (2-3), 91-94, 2001 | 169 | 2001 |
| Shiga toxin/lipopolysaccharide activates caspase-4 and gasdermin D to trigger mitochondrial reactive oxygen species upstream of the NLRP3 inflammasome JM Platnich, H Chung, A Lau, CF Sandall, A Bondzi-Simpson, HM Chen, ... Cell reports 25 (6), 1525-1536. e7, 2018 | 156 | 2018 |
| Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle DP Wilson, C Sutherland, MA Borman, JT Deng, JA MacDonald, ... Biochemical Journal 392 (3), 641-648, 2005 | 137 | 2005 |
| Parasitic helminths: a pharmacopeia of anti-inflammatory molecules MJG Johnston, JA MacDonald, DM McKay Parasitology 136 (2), 125-147, 2009 | 126 | 2009 |
| Extracts of the Rat Tapeworm, Hymenolepis diminuta, Suppress Macrophage Activation In Vitro and Alleviate Chemically Induced Colitis in Mice MJG Johnston, A Wang, MED Catarino, L Ball, VC Phan, JA MacDonald, ... Infection and immunity 78 (3), 1364-1375, 2010 | 121 | 2010 |
| Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition MA Borman, JA MacDonald, A Murányi, DJ Hartshorne, TAJ Haystead Journal of Biological Chemistry 277 (26), 23441-23446, 2002 | 121 | 2002 |
| Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury SA Hirota, K Fines, J Ng, D Traboulsi, J Lee, E Ihara, Y Li, WG Willmore, ... Gastroenterology 139 (1), 259-269. e3, 2010 | 118 | 2010 |
