| Determination and inference of eukaryotic transcription factor sequence specificity MT Weirauch, A Yang, M Albu, AG Cote, A Montenegro-Montero, P Drewe, ... Cell 158 (6), 1431-1443, 2014 | 1861 | 2014 |
| A compendium of RNA-binding motifs for decoding gene regulation D Ray, H Kazan, KB Cook, MT Weirauch, HS Najafabadi, X Li, ... Nature 499 (7457), 172-177, 2013 | 1590 | 2013 |
| The human splicing code reveals new insights into the genetic determinants of disease HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ... Science 347 (6218), 1254806, 2015 | 1486 | 2015 |
| Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy CP Couturier, S Ayyadhury, PU Le, J Nadaf, J Monlong, G Riva, R Allache, ... Nature communications 11 (1), 3406, 2020 | 469 | 2020 |
| C2H2 zinc finger proteins greatly expand the human regulatory lexicon HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ... Nature biotechnology 33 (5), 555-562, 2015 | 373 | 2015 |
| Multiparameter functional diversity of human C2H2 zinc finger proteins FW Schmitges, E Radovani, HS Najafabadi, M Barazandeh, LF Campitelli, ... Genome research 26 (12), 1742-1752, 2016 | 199 | 2016 |
| Systematic discovery of structural elements governing stability of mammalian messenger RNAs H Goodarzi, HS Najafabadi, P Oikonomou, TM Greco, L Fish, R Salavati, ... Nature 485 (7397), 264-268, 2012 | 198 | 2012 |
| Expression of DRD2 is increased in human pancreatic ductal adenocarcinoma and inhibitors slow tumor growth in mice P Jandaghi, HS Najafabadi, AS Bauer, AI Papadakis, M Fassan, A Hall, ... Gastroenterology 151 (6), 1218-1231, 2016 | 133 | 2016 |
| Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer’s disease R Alkallas, L Fish, H Goodarzi, HS Najafabadi Nature communications 8 (1), 909, 2017 | 111 | 2017 |
| Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities K Narasimhan, SA Lambert, AWH Yang, J Riddell, S Mnaimneh, H Zheng, ... Elife 4, e06967, 2015 | 101 | 2015 |
| Sequence-based prediction of protein-protein interactions by means of codon usage HS Najafabadi, R Salavati Genome biology 9 (5), R87, 2008 | 97 | 2008 |
| Spatially mapping the immune landscape of melanoma using imaging mass cytometry D Moldoveanu, LA Ramsay, M Lajoie, L Anderson-Trocme, M Lingrand, ... Science immunology 7 (70), eabi5072, 2022 | 92 | 2022 |
| Nuclear TARBP2 drives oncogenic dysregulation of RNA splicing and decay L Fish, A Navickas, B Culbertson, Y Xu, HCB Nguyen, S Zhang, ... Molecular cell 75 (5), 967-981. e9, 2019 | 74 | 2019 |
| Universal function-specificity of codon usage HS Najafabadi, H Goodarzi, R Salavati Nucleic acids research 37 (21), 7014-7023, 2009 | 72 | 2009 |
| Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle stem cell pool F Lazure, DM Blackburn, AH Corchado, K Sahinyan, N Karam, ... EMBO reports 21 (12), e49499, 2020 | 68 | 2020 |
| A general framework for interrogation of mRNA stability programs identifies RNA-binding proteins that govern cancer transcriptomes G Perron, P Jandaghi, S Solanki, M Safisamghabadi, C Storoz, ... Cell Reports 23 (6), 1639-1650, 2018 | 66 | 2018 |
| Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles N Tawil, R Bassawon, B Meehan, A Nehme, L Montermini, T Gayden, ... Blood advances 5 (6), 1682-1694, 2021 | 64 | 2021 |
| A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity M Garton, HS Najafabadi, FW Schmitges, E Radovani, TR Hughes, ... Nucleic acids research 43 (19), 9147-9157, 2015 | 64 | 2015 |
| A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements L Fish, M Khoroshkin, A Navickas, K Garcia, B Culbertson, B Hänisch, ... Science 372 (6543), eabc7531, 2021 | 62 | 2021 |
| Amino acid and codon usage profiles: adaptive changes in the frequency of amino acids and codons H Goodarzi, N Torabi, HS Najafabadi, M Archetti Gene 407 (1-2), 30-41, 2008 | 60 | 2008 |
Timothy R. HughesUniversity of TorontoVerified email at utoronto.ca
