Alpha S. Yap
Alpha S. Yap
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Molecular and functional analysis of cadherin-based adherens junctions
AS Yap, WM Brieher, BM Gumbiner
Annual review of cell and developmental biology 13 (1), 119-146, 1997
Cadherins and cancer: how does cadherin dysfunction promote tumor progression?
A Jeanes, CJ Gottardi, AS Yap
Oncogene 27 (55), 6920-6929, 2008
The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn
CM Niessen, BM Gumbiner
Journal of Cell Biology 141 (3), 779-789, 1998
Recycling of E-cadherin: a potential mechanism for regulating cadherin dynamics
TL Le, AS Yap, JL Stow
The Journal of cell biology 146 (1), 219-232, 1999
E-cadherin junctions as active mechanical integrators in tissue dynamics
T Lecuit, AS Yap
Nature cell biology 17 (5), 533-539, 2015
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
D Boucher, M Monteleone, RC Coll, KW Chen, CM Ross, JL Teo, ...
Journal of Experimental Medicine 215 (3), 827-840, 2018
Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation
CM Niessen, D Leckband, AS Yap
Physiological reviews 91 (2), 691-731, 2011
Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function
WM Brieher, M Pruschy, BM Gumbiner
Current Biology 7 (5), 308-315, 1997
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell–cell contacts
AM Shewan, M Maddugoda, A Kraemer, SJ Stehbens, S Verma, ...
Molecular biology of the cell 16 (10), 4531-4542, 2005
Lateral dimerization is required for the homophilic binding activity of C-cadherin.
WM Brieher, AS Yap, BM Gumbiner
The Journal of cell biology 135 (2), 487-496, 1996
E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts
EM Kovacs, RG Ali, AJ McCormack
Journal of Biological Chemistry 277 (8), 6708-6718, 2002
Direct cadherin-activated cell signaling: a view from the plasma membrane
AS Yap, EM Kovacs
The Journal of cell biology 160 (1), 11, 2003
Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts
EM Kovacs, M Goodwin, RG Ali, AD Paterson
Current Biology 12 (5), 379-382, 2002
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens
M Smutny, HL Cox, JM Leerberg, EM Kovacs, MA Conti, C Ferguson, ...
Nature cell biology 12 (7), 696-702, 2010
Tensile forces and mechanotransduction at cell–cell junctions
G Charras
Current Biology 28 (8), R445-R457, 2018
Making and breaking contacts: the cellular biology of cadherin regulation
AS Yap, MS Crampton, J Hardin
Current opinion in cell biology 19 (5), 508-514, 2007
Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens
A Ratheesh, GA Gomez, R Priya, S Verma, EM Kovacs, K Jiang, ...
Nature cell biology 14 (8), 818-828, 2012
Contact inhibition (of proliferation) redux
AI McClatchey, AS Yap
Current opinion in cell biology 24 (5), 685-694, 2012
A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells
KC Miranda, T Khromykh, P Christy, TL Le, CJ Gottardi, JL Stow, ...
Journal of Biological Chemistry 276 (25), 22565-22572, 2001
Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia
SK Wu, GA Gomez, M Michael, S Verma, HL Cox, JG Lefevre, RG Parton, ...
Nature cell biology 16 (2), 167, 2014
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