Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma PP Provenzano, C Cuevas, AE Chang, VK Goel, DD Von Hoff, ... Cancer cell 21 (3), 418-429, 2012 | 2209 | 2012 |
Collagen reorganization at the tumor-stromal interface facilitates local invasion PP Provenzano, KW Eliceiri, JM Campbell, DR Inman, JG White, PJ Keely BMC medicine 4 (1), 38, 2006 | 2063 | 2006 |
Collagen density promotes mammary tumor initiation and progression PP Provenzano, DR Inman, KW Eliceiri, JG Knittel, L Yan, CT Rueden, ... BMC medicine 6 (1), 11, 2008 | 1647 | 2008 |
Aligned collagen is a prognostic signature for survival in human breast carcinoma MW Conklin, JC Eickhoff, KM Riching, CA Pehlke, KW Eliceiri, ... The American journal of pathology 178 (3), 1221-1232, 2011 | 1417 | 2011 |
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage PP Provenzano, DR Inman, KW Eliceiri, PJ Keely Oncogene 28 (49), 4326-4343, 2009 | 773 | 2009 |
Matrix nanotopography as a regulator of cell function DH Kim, PP Provenzano, CL Smith, A Levchenko J Cell Biol 197 (3), 351-360, 2012 | 683 | 2012 |
Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling PP Provenzano, PJ Keely Journal of Cell Science 124 (8), 1195-1205, 2011 | 602 | 2011 |
Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization PP Provenzano, DR Inman, KW Eliceiri, SM Trier, PJ Keely Biophysical journal 95 (11), 5374-5384, 2008 | 599 | 2008 |
Collagen fibril morphology and organization: implications for force transmission in ligament and tendon PP Provenzano, R Vanderby Matrix biology 25 (2), 71-84, 2006 | 439 | 2006 |
Nonlinear ligament viscoelasticity P Provenzano, R Lakes, T Keenan, R Vanderby Annals of biomedical engineering 29 (10), 908-914, 2001 | 367 | 2001 |
Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer PP Provenzano, SR Hingorani British journal of cancer 108 (1), 1, 2013 | 343 | 2013 |
Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration A Ray, O Lee, Z Win, RM Edwards, PW Alford, DH Kim, PP Provenzano Nature Communications 8, 14923, 2017 | 293 | 2017 |
Subfailure damage in ligament: a structural and cellular evaluation PP Provenzano, D Heisey, K Hayashi, R Lakes, R Vanderby Journal of Applied Physiology 92 (1), 362-371, 2002 | 278 | 2002 |
Multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) to monitor metastasis and the tumor microenvironment PP Provenzano, KW Eliceiri, PJ Keely Clinical & experimental metastasis 26 (4), 357-370, 2009 | 255 | 2009 |
Application of nonlinear viscoelastic models to describe ligament behavior PP Provenzano, RS Lakes, DT Corr, R Vanderby Biomechanics and modeling in mechanobiology 1 (1), 45-57, 2002 | 230 | 2002 |
Enhanced directional migration of cancer stem cells in 3D aligned collagen matrices A Ray, ZM Slama, RK Morford, SA Madden, PP Provenzano Biophysical journal 112 (5), 1023-1036, 2017 | 179 | 2017 |
Interstitial pressure in pancreatic ductal adenocarcinoma is dominated by a gel-fluid phase CC DuFort, KE DelGiorno, MA Carlson, RJ Osgood, C Zhao, Z Huang, ... Biophysical journal 110 (9), 2106-2119, 2016 | 173 | 2016 |
Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer PP Provenzano, DR Inman, KW Eliceiri, HE Beggs, PJ Keely The American journal of pathology 173 (5), 1551-1565, 2008 | 167 | 2008 |
Fluorescence lifetime imaging of endogenous fluorophores in histopathology sections reveals differences between normal and tumor epithelium in carcinoma in situ of the breast MW Conklin, PP Provenzano, KW Eliceiri, R Sullivan, PJ Keely Cell biochemistry and biophysics 53 (3), 145-157, 2009 | 156 | 2009 |
Nonlinear viscoelasticity in rabbit medial collateral ligament RV Hingorani, PP Provenzano, RS Lakes, A Escarcega, R Vanderby Annals of Biomedical Engineering 32 (2), 306-312, 2004 | 148 | 2004 |