Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that β-cell death is caspase mediated, partially dependent … R Lupi, F Dotta, L Marselli, S Del Guerra, M Masini, C Santangelo, ... Diabetes 51 (5), 1437-1442, 2002 | 855 | 2002 |
Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients M Anello, R Lupi, D Spampinato, S Piro, M Masini, U Boggi, S Del Prato, ... Diabetologia 48, 282-289, 2005 | 437 | 2005 |
Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress S Piro, M Anello, C Di Pietro, MN Lizzio, G Patan, AM Rabuazzo, ... Metabolism-Clinical and Experimental 51 (10), 1340-1347, 2002 | 395 | 2002 |
Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease L Spadaro, O Magliocco, D Spampinato, S Piro, C Oliveri, C Alagona, ... Digestive and Liver Disease 40 (3), 194-199, 2008 | 362 | 2008 |
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells. G Patanè, S Piro, AM Rabuazzo, M Anello, R Vigneri, F Purrello Diabetes 49 (5), 735-740, 2000 | 286 | 2000 |
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets P Marchetti, R Lupi, M Bugliani, CL Kirkpatrick, G Sebastiani, FA Grieco, ... Diabetologia 55, 3262-3272, 2012 | 270 | 2012 |
Lipotoxicity in human pancreatic islets and the protective effect of metformin R Lupi, S Del Guerra, V Fierabracci, L Marselli, M Novelli, G Patane, ... Diabetes 51 (suppl_1), S134-S137, 2002 | 238 | 2002 |
Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome … G Patane, M Anello, S Piro, R Vigneri, F Purrello, AM Rabuazzo Diabetes 51 (9), 2749-2756, 2002 | 230 | 2002 |
Pathophysiological, molecular and therapeutic issues of nonalcoholic fatty liver disease: an overview S Marchisello, A Di Pino, R Scicali, F Urbano, S Piro, F Purrello, ... International journal of molecular sciences 20 (8), 1948, 2019 | 209 | 2019 |
Insulin Secretory Function Is Impaired in Isolated Human Islets Carrying the Gly972→Arg IRS-1 Polymorphism P Marchetti, R Lupi, M Federici, L Marselli, M Masini, U Boggi, ... Diabetes 51 (5), 1419-1424, 2002 | 154 | 2002 |
Cellular and molecular effects of protons: apoptosis induction and potential implications for cancer therapy C Di Pietro, S Piro, G Tabbi, M Ragusa, V Di Pietro, V Zimmitti, F Cuda, ... Apoptosis 11, 57-66, 2006 | 113 | 2006 |
Assessment of adrenocortical reserve in stable patients with cirrhosis G Fede, L Spadaro, T Tomaselli, G Privitera, S Piro, AM Rabuazzo, ... Journal of hepatology 54 (2), 243-250, 2011 | 105 | 2011 |
High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes A Di Pino, W Currenti, F Urbano, R Scicali, S Piro, F Purrello, ... Nutrition, Metabolism and Cardiovascular Diseases 27 (11), 978-984, 2017 | 90 | 2017 |
Cardiovascular risk profile in subjects with prediabetes and new-onset type 2 diabetes identified by HbA1c according to American diabetes association criteria A Di Pino, R Scicali, S Calanna, F Urbano, C Mantegna, AM Rabuazzo, ... Diabetes Care 37 (5), 1447-1453, 2014 | 88 | 2014 |
Direct apoptotic effects of free fatty acids on human endothelial cells S Piro, D Spampinato, L Spadaro, CE Oliveri, F Purrello, AM Rabuazzo Nutrition, Metabolism and Cardiovascular Diseases 18 (2), 96-104, 2008 | 79 | 2008 |
Atorvastatin but not pravastatin impairs mitochondrial function in human pancreatic islets and rat β-cells. Direct effect of oxidative stress F Urbano, M Bugliani, A Filippello, A Scamporrino, S Di Mauro, A Di Pino, ... Scientific reports 7 (1), 11863, 2017 | 74 | 2017 |
Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors CL Kirkpatrick, P Marchetti, F Purrello, S Piro, M Bugliani, D Bosco, ... PloS one 5 (6), e11053, 2010 | 68 | 2010 |
Th2 cytokines have a partial, direct protective effect on the function and survival of isolated human islets exposed to combined proinflammatory and Th1 cytokines L Marselli, F Dotta, S Piro, C Santangelo, M Masini, R Lupi, M Realacci, ... The Journal of Clinical Endocrinology & Metabolism 86 (10), 4974-4978, 2001 | 67 | 2001 |
miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to … D Barbagallo, S Piro, AG Condorelli, LG Mascali, F Urbano, N Parrinello, ... Bmc Genomics 14, 1-12, 2013 | 65 | 2013 |
Lipid and liver abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes S Calanna, R Scicali, A Di Pino, FK Knop, S Piro, AM Rabuazzo, ... Nutrition, Metabolism and Cardiovascular Diseases 24 (6), 670-676, 2014 | 61 | 2014 |