David Hansen
David Hansen
Associate Professor, Brigham Young University
Verified email at
Cited by
Cited by
Microglia in Alzheimer’s disease
DV Hansen, JE Hanson, M Sheng
Journal of Cell Biology 217 (2), 459-472, 2018
Development and evolution of the human neocortex
JH Lui, DV Hansen, AR Kriegstein
Cell 146 (1), 18-36, 2011
Neurogenic radial glia in the outer subventricular zone of human neocortex
DV Hansen, JH Lui, PRL Parker, AR Kriegstein
Nature 464 (7288), 554-561, 2010
Diverse brain myeloid expression profiles reveal distinct microglial activation states and aspects of Alzheimer’s disease not evident in mouse models
BA Friedman, K Srinivasan, G Ayalon, WJ Meilandt, H Lin, MA Huntley, ...
Cell reports 22 (3), 832-847, 2018
TREM2, microglia, and neurodegenerative diseases
FL Yeh, DV Hansen, M Sheng
Trends in molecular medicine 23 (6), 512-533, 2017
Complement C3 is activated in human AD brain and is required for neurodegeneration in mouse models of amyloidosis and tauopathy
T Wu, B Dejanovic, VD Gandham, A Gogineni, R Edmonds, S Schauer, ...
Cell reports 28 (8), 2111-2123. e6, 2019
Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses
K Srinivasan, BA Friedman, JL Larson, BE Lauffer, LD Goldstein, ...
Nature communications 7 (1), 1-16, 2016
Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences
DV Hansen, JH Lui, P Flandin, K Yoshikawa, JL Rubenstein, ...
Nature neuroscience 16 (11), 1576-1587, 2013
Plk1 Regulates Activation of the Anaphase Promoting Complex by Phosphorylating and Triggering SCFβTrCP-dependent Destruction of the APC Inhibitor Emi1
DV Hansen, AV Loktev, KH Ban, PK Jackson
Molecular biology of the cell 15 (12), 5623-5634, 2004
A high-resolution enhancer atlas of the developing telencephalon
A Visel, L Taher, H Girgis, D May, O Golonzhka, RV Hoch, GL McKinsey, ...
Cell 152 (4), 895-908, 2013
Alzheimer’s patient microglia exhibit enhanced aging and unique transcriptional activation
K Srinivasan, BA Friedman, A Etxeberria, MA Huntley, MP van Der Brug, ...
Cell reports 31 (13), 107843, 2020
Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor
JJ Miller, MK Summers, DV Hansen, MV Nachury, NL Lehman, A Loktev, ...
Genes & development 20 (17), 2410-2420, 2006
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex
BE LaMonica, JH Lui, DV Hansen, AR Kriegstein
Nature communications 4 (1), 1-11, 2013
Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis
S Madgwick, DV Hansen, M Levasseur, PK Jackson, KT Jones
The Journal of cell biology 174 (6), 791-801, 2006
A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs
JJ Tung, DV Hansen, KH Ban, AV Loktev, MK Summers, JR Adler III, ...
Proceedings of the National Academy of Sciences 102 (12), 4318-4323, 2005
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
SH Lee, WJ Meilandt, L Xie, VD Gandham, H Ngu, KH Barck, ...
Neuron 109 (8), 1283-1301. e6, 2021
CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit
DV Hansen, JJ Tung, PK Jackson
Proceedings of the National Academy of Sciences 103 (3), 608-613, 2006
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death
MK Wetzel-Smith, J Hunkapiller, TR Bhangale, K Srinivasan, JA Maloney, ...
Nature medicine 20 (12), 1452-1457, 2014
Deriving excitatory neurons of the neocortex from pluripotent stem cells
DV Hansen, JLR Rubenstein, AR Kriegstein
Neuron 70 (4), 645-660, 2011
Trem2 deletion reduces late-stage amyloid plaque accumulation, elevates the Aβ42: Aβ40 ratio, and exacerbates axonal dystrophy and dendritic spine loss in the PS2APP Alzheimer …
WJ Meilandt, H Ngu, A Gogineni, G Lalehzadeh, SH Lee, K Srinivasan, ...
Journal of Neuroscience 40 (9), 1956-1974, 2020
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