p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor J Yun, HD Chae, HE Choy, J Chung, HS Yoo, MH Han, DY Shin Journal of Biological Chemistry 274 (42), 29677-29682, 1999 | 205 | 1999 |
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease EK Thomas, JA Cancelas, HD Chae, AD Cox, PJ Keller, D Perrotti, ... Cancer cell 12 (5), 467-478, 2007 | 173 | 2007 |
Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest M Park, HD Chae, J Yun, M Jung, YS Kim, SH Kim, MH Han, DY Shin Cancer Research 60 (3), 542-545, 2000 | 147 | 2000 |
RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development Y Gu, HD Chae, JE Siefring, AC Jasti, DA Hildeman, DA Williams Nature immunology 7 (11), 1182-1190, 2006 | 127 | 2006 |
Epigenetic regulation of NANOG by miR-302 cluster-MBD2 completes induced pluripotent stem cell reprogramming MR Lee, N Prasain, HD Chae, YJ Kim, C Mantel, MC Yoder, ... Stem cells 31 (4), 666-681, 2013 | 118 | 2013 |
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse X Ou, HD Chae, RH Wang, WC Shelley, S Cooper, T Taylor, YJ Kim, ... Blood, The Journal of the American Society of Hematology 117 (2), 440-450, 2011 | 117 | 2011 |
SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells HD Chae, HE Broxmeyer Stem cells and development 20 (7), 1277-1285, 2011 | 112 | 2011 |
p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor MS Jung, J Yun, HD Chae, JM Kim, SC Kim, TS Choi, DY Shin Oncogene 20 (41), 5818-5825, 2001 | 112 | 2001 |
Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway J Yun, HD Chae, TS Choi, EH Kim, YJ Bang, J Chung, KS Choi, ... Journal of Biological Chemistry 278 (38), 36966-36972, 2003 | 106 | 2003 |
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells HD Chae, KE Lee, DA Williams, Y Gu Blood, The Journal of the American Society of Hematology 111 (5), 2597-2605, 2008 | 93 | 2008 |
Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation TD Kim, JS Kim, JH Kim, J Myung, HD Chae, KC Woo, SK Jang, DS Koh, ... Molecular and cellular biology, 2005 | 93 | 2005 |
Cdk2-dependent phosphorylation of the NF-Y transcription factor is essential for the expression of the cell cycle-regulatory genes and cell cycle G1/S and G2/M transitions HD Chae, J Yun, YJ Bang, DY Shin Oncogene 23 (23), 4084-4088, 2004 | 91 | 2004 |
Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors HD Chae, TS Choi, BM Kim, JH Jung, YJ Bang, DY Shin Oncogene 24 (30), 4813-4819, 2005 | 82 | 2005 |
Bcl-xL and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation MS Jung, DH Jin, HD Chae, S Kang, SC Kim, YJ Bang, TS Choi, K Choi, ... Journal of Biological Chemistry 279 (17), 17765-17771, 2004 | 65 | 2004 |
Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS J Kim, SY Kim, BM Kim, H Lee, I Kim, J Yun, Y Jo, T Oh, Y Jo, HD Chae, ... Journal of Biological Chemistry 288 (17), 12014-12021, 2013 | 55 | 2013 |
5-Aminoimidazole-4-carboxyamide Ribonucleoside Induces G1/S Arrest and Nanog Downregulation via p53 and Enhances Erythroid Differentiation HD Chae, MR Lee, HE Broxmeyer Stem Cells 30 (2), 140-149, 2012 | 50 | 2012 |
Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells B Mitton, HD Chae, K Hsu, R Dutta, G Aldana-Masangkay, R Ferrari, ... Leukemia 30 (12), 2302-2311, 2016 | 45 | 2016 |
RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling HD Chae, JE Siefring, DA Hildeman, Y Gu, DA Williams PloS one 5 (11), e13970, 2010 | 45 | 2010 |
Protein kinase C regulates the activity and stability of serotonin N‐acetyltransferase BH Choi, HD Chae, TJ Park, J Oh, J Lim, SS Kang, H Ha, KT Kim Journal of neurochemistry 90 (2), 442-454, 2004 | 39 | 2004 |
Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA HD Chae, B Mitton, NJ Lacayo, KM Sakamoto Leukemia 29 (6), 1379-1389, 2015 | 37 | 2015 |