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Shang-Yang Chen
Shang-Yang Chen
Dyno Therapeutics
Verified email at dynotx.com
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Year
Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function
KA Helmin, L Morales-Nebreda, MAT Acosta, KR Anekalla, SY Chen, ...
The Journal of clinical investigation 130 (12), 6571-6587, 2020
682020
DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice
SA McGrath-Morrow, R Ndeh, KA Helmin, SY Chen, KR Anekalla, ...
Journal of Biological Chemistry 293 (30), 11772-11783, 2018
432018
Critical role of synovial tissue–resident macrophage niche in joint homeostasis and suppression of chronic inflammation
QQ Huang, R Doyle, SY Chen, Q Sheng, AV Misharin, Q Mao, DR Winter, ...
Science Advances 7 (2), eabd0515, 2021
282021
Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations
SA Taylor, SY Chen, G Gadhvi, L Feng, KD Gromer, H Abdala-Valencia, ...
PLoS One 16 (1), e0244743, 2021
202021
Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality
CM Koch, KR Anekalla, YS Hu, JM Davis, M Ciesielski, G Gadhvi, ...
bioRxiv, 2020.06. 08.141309, 2020
32020
Macrophages drive the inflammatory phase in experimental osteoarthritis
A Montgomery, N Fahy, S Hamilton, B Eckman, L De Almeida, S Ishihara, ...
bioRxiv, 2020.05. 28.122408, 2020
32020
Tissue-resident, extravascular Ly6c− monocytes are critical for inflammation in the synovium
AB Montgomery, SY Chen, Y Wang, G Gadhvi, MG Mayr, CM Cuda, ...
Cell reports 42 (5), 2023
22023
MAGNET: A web-based application for gene set enrichment analysis using macrophage data sets
SY Chen, G Gadhvi, DR Winter
Plos one 18 (1), e0272166, 2023
12023
Arthritis-associated Synovial CD64-Ly6c-myeloid Cells Comprise 2 Subpopulations
Y Wang, M Gurra, C Cuda, H Makinde, S Chen, G Gadhvi, S Dominguez, ...
ARTHRITIS & RHEUMATOLOGY 74, 3377-3379, 2022
2022
Disease-associated microglia are implicated in neuropsychiatric manifestations of systemic lupus erythematosus
HM Makinde, SY Chen, EV Mike, C Putterman, DR Winter, CM Cuda
The Journal of Immunology 206 (1_Supplement), 60.01-60.01, 2021
2021
Tissue-resident, extravascular CD64-Ly6C- population forms a critical barrier for inflammation in the synovium
AB Montgomery, SY Chen, G Gadhvi, MG Mayr, CM Cuda, S Dominguez, ...
bioRxiv, 2021.02. 25.432850, 2021
2021
TRANSCRIPTIONAL PROFILING OF PEDIATRIC CHOLESTATIC LIVERS IDENTIFIES THREE DISTINCT MACROPHAGE POPULATIONS
SA Taylor, SY Chen, G Gadhvi, KD Gromer, H Abdala-Valencia, L Ostilla, ...
The Liver Meeting Digital Experience™, 2020
2020
The Dynamics of Macrophage Sub-Populations in the Inflammatory Phase Following Joint Trauma
S Hamilton, A Montgomery, N Fahy, M Mayr, SY Chen, G Gadhvi, ...
ARTHRITIS & RHEUMATOLOGY 72, 2020
2020
Characterizing Heterogeneity of Synovial Macrophages in Rheumatoid Arthritis Patients
SY Chen, Y Wang, A Montgomery, S Dominguez, C Cuda, G Gadhvi, ...
ARTHRITIS & RHEUMATOLOGY 72, 2020
2020
A Novel Subclass of Intravascular Non-classical, Tissue Resident Synovial Monocyte Is Critical for Rheumatoid Arthritis Pathogenesis
A Montgomery, SY Chen, D Winter, H Perlman
ARTHRITIS & RHEUMATOLOGY 71, 2019
2019
The Role of Flip in Differentiation and Survival of Synovial Tissue Resident Macrophages
Q Huang, R Doyle, SY Chen, A Misharin, D Winter, R Pope
ARTHRITIS & RHEUMATOLOGY 71, 2019
2019
Single Cell RNA-sequencing Reveals Distinct Macrophage Subsets in the Joint with Differing Ontogenies During Steady-state and Arthritis
A Montgomery, SY Chen, P Homan, G Gadhvi, D Winte, H Perlman
ARTHRITIS & RHEUMATOLOGY 71, 2019
2019
Tissue Resident Macrophages Establish a Niche That Limits Monocyte to Macrophage Differentiation in Synovial Tissue during Homeostasis
QQ Huang
2018 ACR/ARHP Annual Meeting, 2018
2018
Loss of Synovial Tissue Resident Macrophages Permits Monocyte to Macrophage Differentiation and Inflammation in Hupo Mice
QQ Huang
2018 ACR/ARHP Annual Meeting, 2018
2018
DNA Methylation as a Driver of the Neonatal CD4+ T Cell Response to Pneumonia
BD Singer, K Helmin, SY Chen, K Anekalla, R Ndeh, J Collaco, ...
D54. INTERPLAY OF DIVERSE CELLULAR AND MOLECULAR PATHWAYS IN ASTHMA AND …, 2018
2018
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