'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data JK Nicholson, JC Lindon, E Holmes xenobiotica 29 (11), 1181-1189, 1999 | 5985* | 1999 |
Proposed minimum reporting standards for chemical analysis: chemical analysis working group (CAWG) metabolomics standards initiative (MSI) LW Sumner, A Amberg, D Barrett, MH Beale, R Beger, CA Daykin, ... Metabolomics 3, 211-221, 2007 | 4427 | 2007 |
Metabonomics: a platform for studying drug toxicity and gene function JK Nicholson, J Connelly, JC Lindon, E Holmes Nature reviews Drug discovery 1 (2), 153-161, 2002 | 2595 | 2002 |
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692, 2007 | 2348 | 2007 |
Metabonomics JK Nicholson, JC Lindon Nature 455 (7216), 1054-1056, 2008 | 2293 | 2008 |
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ... Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006 | 1292 | 2006 |
Pharmaco-metabonomic phenotyping and personalized drug treatment T Andrew Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ... Nature 440 (7087), 1073-1077, 2006 | 1064 | 2006 |
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ... Analytical chemistry 77 (5), 1282-1289, 2005 | 1032 | 2005 |
Pattern recognition methods and applications in biomedical magnetic resonance JC Lindon, E Holmes, JK Nicholson Progress in Nuclear Magnetic Resonance Spectroscopy 39 (1), 1-40, 2001 | 970* | 2001 |
Encyclopedia of spectroscopy and spectrometry JC Lindon, GE Tranter, D Koppenaal Academic Press, 2016 | 938* | 2016 |
Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism TA Clayton, D Baker, JC Lindon, JR Everett, JK Nicholson Proceedings of the National Academy of Sciences 106 (34), 14728-14733, 2009 | 934 | 2009 |
NMR spectroscopy using liquid crystal solvents JW Emsley, JC Lindon Elsevier, 2018 | 796 | 2018 |
Improved WATERGATE pulse sequences for solvent suppression in NMR spectroscopy M Liu, X Mao, C Ye, H Huang, JK Nicholson, JC Lindon Journal of Magnetic Resonance 132 (1), 125-129, 1998 | 693 | 1998 |
Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR … O Cloarec, ME Dumas, J Trygg, A Craig, RH Barton, JC Lindon, ... Analytical chemistry 77 (2), 517-526, 2005 | 659 | 2005 |
Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids JC Lindon, JK Nicholson, E Holmes, JR Everett Concepts in Magnetic Resonance: An Educational Journal 12 (5), 289-320, 2000 | 633 | 2000 |
Scaling and normalization effects in NMR spectroscopic metabonomic data sets A Craig, O Cloarec, E Holmes, JK Nicholson, JC Lindon Analytical chemistry 78 (7), 2262-2267, 2006 | 624 | 2006 |
Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis JC Lindon, E Holmes, ME Bollard, EG Stanley, JK Nicholson Biomarkers 9 (1), 1-31, 2004 | 623 | 2004 |
A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model FPJ Martin, ME Dumas, Y Wang, C Legido‐Quigley, IKS Yap, H Tang, ... Molecular systems biology 3 (1), 112, 2007 | 597 | 2007 |
NMR‐based metabonomic approaches for evaluating physiological influences on biofluid composition ME Bollard, EG Stanley, JC Lindon, JK Nicholson, E Holmes NMR in Biomedicine: An International Journal Devoted to the Development and …, 2005 | 593 | 2005 |
Metabolic phenotyping in clinical and surgical environments JK Nicholson, E Holmes, JM Kinross, AW Darzi, Z Takats, JC Lindon Nature 491 (7424), 384-392, 2012 | 585 | 2012 |