| Targeting Candida albicans filamentation for antifungal drug development T Vila, JA Romo, CG Pierce, SF McHardy, SP Saville, JL Lopez-Ribot Virulence 8 (2), 150-158, 2017 | 169 | 2017 |
| Reductive cleavage of N O bonds in hydroxylamines and hydroxamic acid derivatives using samarium diiodide GE Keck, TT Wager, SF McHardy Tetrahedron 55 (40), 11755-11772, 1999 | 152 | 1999 |
| A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance CG Pierce, AK Chaturvedi, AL Lazzell, AT Powell, SP Saville, SF McHardy, ... npj Biofilms and Microbiomes 1 (1), 1-8, 2015 | 132 | 2015 |
| Total synthesis of (+)-7-deoxypancratistatin: A radical cyclization approach GE Keck, SF McHardy, JA Murry Journal of the American Chemical Society 117 (27), 7289-7290, 1995 | 131 | 1995 |
| Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015) SF McHardy, HYL Wang, SV McCowen, MC Valdez Expert opinion on therapeutic patents 27 (4), 455-476, 2017 | 127 | 2017 |
| Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation JA Romo, CG Pierce, AK Chaturvedi, AL Lazzell, SF McHardy, SP Saville, ... MBio 8 (6), 10.1128/mbio. 01991-17, 2017 | 102 | 2017 |
| A second-generation radical-based synthesis of (+)-7-deoxypancratistatin GE Keck, TT Wager, SF McHardy The Journal of Organic Chemistry 63 (25), 9164-9165, 1998 | 77 | 1998 |
| Total synthesis of (+)-carbonolide B GE Keck, A Palani, SF McHardy The Journal of Organic Chemistry 59 (11), 3113-3122, 1994 | 77 | 1994 |
| Structure–Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase H Neelakantan, HY Wang, V Vance, JD Hommel, SF McHardy, ... Journal of medicinal chemistry 60 (12), 5015-5028, 2017 | 69 | 2017 |
| Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice H Neelakantan, V Vance, MD Wetzel, HYL Wang, SF McHardy, ... Biochemical pharmacology 147, 141-152, 2018 | 68 | 2018 |
| Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle H Neelakantan, CR Brightwell, TG Graber, R Maroto, HYL Wang, ... Biochemical pharmacology 163, 481-492, 2019 | 65 | 2019 |
| Design and Discovery of a Selective Small Molecule κ Opioid Antagonist (2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine, PF … PR Verhoest, A Sawant Basak, V Parikh, M Hayward, GW Kauffman, ... Journal of medicinal chemistry 54 (16), 5868-5877, 2011 | 57 | 2011 |
| Diastereoselective 6-exo Radical Cyclizations of Oxime Ethers: Total Synthesis of 7-Deoxypancratistatin GE Keck, SF McHardy, JA Murry The Journal of Organic Chemistry 64 (12), 4465-4476, 1999 | 47 | 1999 |
| Some unusual reactions of Weinreb amides GE Keck, SF McHardy, JA Murry Tetrahedron letters 34 (39), 6215-6218, 1993 | 45 | 1993 |
| Reductive cleavage of NO bonds in hydroxylamine and hydroxamic acid derivatives using SmI 2/THF GE Keck, SF McHardy, TT Wager Tetrahedron letters 41 (36), 7419-7422, 1995 | 37 | 1995 |
| 4-Phenyl-piperidine compounds and their use as modulators of opioid receptors S McHardy, S Liras, S Guediche, J Coe US Patent App. 10/762,447, 2004 | 36 | 2004 |
| Structure–activity relationships of new natural product-based diaryloxazoles with selective activity against androgen receptor-positive breast cancer cells AJ Robles, S McCowen, S Cai, M Glassman, F Ruiz, RH Cichewicz, ... Journal of medicinal chemistry 60 (22), 9275-9289, 2017 | 34 | 2017 |
| 2-Azabicyclo [3.3. 1] nonane derivatives JW Coe, S McHardy US Patent 7,056,930, 2006 | 33 | 2006 |
| 3-azabicyclo [3.1. 0] hexane derivatives SF McHardy, S Liras, SD Heck US Patent 7,049,335, 2006 | 32 | 2006 |
| A modular PROTAC design for target destruction using a degradation signal based on a single amino acid K Shanmugasundaram, P Shao, H Chen, B Campos, SF McHardy, T Luo, ... Journal of Biological Chemistry 294 (41), 15172-15175, 2019 | 30 | 2019 |
Spiros LirasApple Tree PartnersVerified email at appletreepartners.com
