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Eric Wang
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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ...
Nature 478 (7370), 524-528, 2011
20692011
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
J Shi, E Wang, JP Milazzo, Z Wang, JB Kinney, CR Vakoc
Nature biotechnology 33 (6), 661-667, 2015
7482015
Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ...
Genes & development 27 (24), 2648-2662, 2013
4662013
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ...
Genes & development 25 (15), 1628-1640, 2011
2952011
Targeting an RNA-binding protein network in acute myeloid leukemia
E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ...
Cancer cell 35 (3), 369-384. e7, 2019
2402019
A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit
GA Blobel, S Kadauke, E Wang, AW Lau, J Zuber, MM Chou, CR Vakoc
Molecular cell 36 (6), 970-983, 2009
2122009
Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment
X Chen, C Glytsou, H Zhou, S Narang, DE Reyna, A Lopez, ...
Cancer discovery 9 (7), 890-909, 2019
1972019
RNA splicing and cancer
E Wang, I Aifantis
Trends in cancer 6 (8), 631-644, 2020
1562020
NSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler
C Shen, JJ Ipsaro, J Shi, JP Milazzo, E Wang, JS Roe, Y Suzuki, ...
Molecular cell 60 (6), 847-859, 2015
1552015
Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia
E Wang, S Kawaoka, M Yu, J Shi, T Ni, W Yang, J Zhu, RG Roeder, ...
Proceedings of the National Academy of Sciences 110 (10), 3901-3906, 2013
1492013
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ...
Cell 184 (15), 4032-4047. e31, 2021
1372021
The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9; NrasG12D acute myeloid leukemia
J Shi, E Wang, J Zuber, A Rappaport, M Taylor, C Johns, SW Lowe, ...
Oncogene 32 (7), 930-938, 2013
1302013
MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis
B Aranda-Orgilles, R Saldaņa-Meyer, E Wang, E Trompouki, A Fassl, ...
Cell stem cell 19 (6), 784-799, 2016
1092016
Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors
E Wang, X Mi, MC Thompson, S Montoya, RQ Notti, J Afaghani, ...
New England Journal of Medicine 386 (8), 735-743, 2022
1032022
The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia
D Papaioannou, A Petri, OM Dovey, S Terreri, E Wang, FA Collins, ...
Nature communications 10 (1), 5351, 2019
792019
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ...
Nature genetics 53 (5), 707-718, 2021
722021
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies
GM Matthews, P Mehdipour, LA Cluse, KJ Falkenberg, E Wang, M Roth, ...
Blood, The Journal of the American Society of Hematology 126 (21), 2392-2403, 2015
562015
The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma
N Bharathy, NE Berlow, E Wang, J Abraham, TP Settelmeyer, JE Hooper, ...
Science signaling 11 (557), eaau7632, 2018
532018
The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer
E Wang, S Kawaoka, JS Roe, J Shi, AF Hohmann, Y Xu, AS Bhagwat, ...
Elife 4, e06377, 2015
422015
Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation
E Wang, H Zhou, B Nadorp, G Cayanan, X Chen, AH Yeaton, S Nomikou, ...
Cell Stem Cell 28 (4), 718-731. e6, 2021
412021
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