| The ECVAM International Validation Study on In Vitro Embryotoxicity Tests: Results of the Definitive Phase and Evaluation of Prediction Models E Genschow, H Spielmann, G Scholz, A Seiler, N Brown, A Piersma, ... Alternatives to laboratory animals 30 (2), 151-176, 2002 | 487 | 2002 |
| Validation of the Embryonic Stem Cell Test in the International ECVAM Validation Study on Three In Vitro Embryotoxicity Tests E Genschow, H Spielmann, G Scholz, I Pohl, A Seiler, N Clemann, ... Alternatives to laboratory animals 32 (3), 209-244, 2004 | 402 | 2004 |
| The embryonic stem cell test, an in vitro embryotoxicity test using two permanent mouse cell lines: 3T3 fibroblasts and embryonic stem cells H Spielmann, I Pohl, B Doring, M Liebsch, F Moldenhauer In Vitro Toxicology 10 (1), 119-128, 1997 | 343 | 1997 |
| The international EU/COLIPA in vitro phototoxicity validation study: results of phase II (blind trial). Part 1: the 3T3 NRU phototoxicity test H Spielmann, M Balls, J Dupuis, WJ Pape, G Pechovitch, O De Silva, ... Toxicology in vitro 12 (3), 305-327, 1998 | 340 | 1998 |
| Report and recommendations of the CAAT/ERGATT workshop on the validation of toxicity test procedures M Balls, B Blaauboer, D Brusick, J Frazier, D Lamb, M Pemberton, ... Alternatives to Laboratory Animals 18 (1_part_1), 313-337, 1990 | 325 | 1990 |
| The validated embryonic stem cell test to predict embryotoxicity in vitro AEM Seiler, H Spielmann Nature protocols 6 (7), 961-978, 2011 | 321 | 2011 |
| Practical Aspects of the Validation of Toxicity Test Procedures: The Report and Recommendations of ECVAM Workshop 5, M Balls, BJ Blaauboer, JH Fentem, L Bruner, RD Combes, B Ekwall, ... Alternatives to laboratory animals 23 (1), 129-146, 1995 | 315 | 1995 |
| The EC/HO international validation study on alternatives to the Draize eye irritation test M Balls, PA Botham, LH Bruner, H Spielmann Toxicology in vitro 9 (6), 871-929, 1995 | 302 | 1995 |
| Arzneimittel in Schwangerschaft und Stillzeit C Schaefer, H Spielmann, K Vetter, C Weber-Schöndorfer Elsevier Health Sciences, 2017 | 299 | 2017 |
| The Production of Avian (Egg Yolk) Antibodies: IgY: The Report and Recommendations of ECVAM Workshop 211,2 R Schade, C Staak, C Hendriksen, M Erhard, H Hugl, G Koch, A Larsson, ... Alternatives to laboratory animals 24 (6), 925-934, 1996 | 290 | 1996 |
| The Three Rs: The Way Forward: The Report and Recommendations of ECVAM Workshop 11, M Balls, AM Goldberg, JH Fentem, CL Broadhead, RL Burch, ... Alternatives to Laboratory Animals 23 (6), 838-866, 1995 | 280 | 1995 |
| The use of reconstructed human epidermis for skin absorption testing: results of the validation study M Schäfer-Korting, U Bock, W Diembeck, HJ Düsing, A Gamer, ... Alternatives to Laboratory Animals 36 (2), 161-187, 2008 | 268 | 2008 |
| The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity … H Spielmann, S Hoffmann, M Liebsch, P Botham, JH Fentem, C Eskes, ... Alternatives to laboratory animals 35 (6), 559-601, 2007 | 248 | 2007 |
| Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation T Höfer, I Gerner, U Gundert-Remy, M Liebsch, A Schulte, H Spielmann, ... Archives of toxicology 78, 549-564, 2004 | 241 | 2004 |
| Embryotoxicity screening using embryonic stem cells in vitro: correlation to in vivo teratogenicity G Scholz, I Pohl, E Genschow, M Klemm, H Spielmann Cells Tissues Organs 165 (3-4), 203-211, 1999 | 212 | 1999 |
| Improvement of an in vitro stem cell assay for developmental toxicity: the use of molecular endpoints in the embryonic stem cell test A Seiler, A Visan, R Buesen, E Genschow, H Spielmann Reproductive toxicology 18 (2), 231-240, 2004 | 205 | 2004 |
| A proposed eye irritation testing strategy to reduce and replace in vivo studies using bottom–up and top–down approaches L Scott, C Eskes, S Hoffmann, E Adriaens, N Alepée, M Bufo, R Clothier, ... Toxicology in Vitro 24 (1), 1-9, 2010 | 202 | 2010 |
| The role of prevalidation in the development, validation and acceptance of alternative methods RD Curren, JA Southee, H Spielmann, M Liebsch, JH Fentem, M Balls Alternatives to Laboratory Animals 23 (2), 211-217, 1995 | 194 | 1995 |
| A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment S Scholz, E Sela, L Blaha, T Braunbeck, M Galay-Burgos, ... Regulatory toxicology and pharmacology 67 (3), 506-530, 2013 | 192 | 2013 |
| Prevalidation of the embryonic stem cell test (EST)—a new in vitro embryotoxicity test G Scholz, E Genschow, I Pohl, S Bremer, M Paparella, H Raabe, ... Toxicology in vitro 13 (4-5), 675-681, 1999 | 189 | 1999 |
