David S. Perlin
David S. Perlin
Hackensack Meridian Health Center for Discovery and Innovation
Verified email at - Homepage
Cited by
Cited by
The global problem of antifungal resistance: prevalence, mechanisms, and management
DS Perlin, R Rautemaa-Richardson, A Alastruey-Izquierdo
The Lancet infectious diseases 17 (12), e383-e392, 2017
Frequency and evolution of azole resistance in Aspergillus fumigatus associated with treatment failure
SJ Howard, D Cerar, MJ Anderson, A Albarrag, MC Fisher, ...
Emerging infectious diseases 15 (7), 1068, 2009
Increasing Echinocandin Resistance in Candida glabrata: Clinical Failure Correlates With Presence of FKS Mutations and Elevated Minimum Inhibitory …
BD Alexander, MD Johnson, CD Pfeiffer, C Jiménez-Ortigosa, J Catania, ...
Clinical infectious diseases 56 (12), 1724-1732, 2013
Resistance to echinocandin-class antifungal drugs
DS Perlin
Drug Resistance Updates 10 (3), 121-130, 2007
Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard, SJ Howard, PD Rogers, DS Perlin
Cold Spring Harbor perspectives in medicine 5 (7), a019752, 2015
Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates
S Park, R Kelly, JN Kahn, J Robles, MJ Hsu, E Register, W Li, V Vyas, ...
Antimicrobial agents and chemotherapy 49 (8), 3264-3273, 2005
A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and …
A Chowdhary, A Prakash, C Sharma, M Kordalewska, A Kumar, S Sarma, ...
Journal of Antimicrobial Chemotherapy 73 (4), 891-899, 2018
Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
BM Hover, SH Kim, M Katz, Z Charlop-Powers, JG Owen, MA Ternei, ...
Nature microbiology 3 (4), 415-422, 2018
Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria
MA Pfaller, DJ Diekema, D Andes, MC Arendrup, SD Brown, SR Lockhart, ...
Drug Resistance Updates 14 (3), 164-176, 2011
A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Accounts for …
G Garcia-Effron, SK Katiyar, S Park, TD Edlind, DS Perlin
Antimicrobial agents and chemotherapy 52 (7), 2305-2312, 2008
High-frequency triazole resistance found in nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease
DW Denning, S Park, C Lass-Florl, MG Fraczek, M Kirwan, R Gore, ...
Clinical infectious diseases 52 (9), 1123-1129, 2011
Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β-d-Glucan Synthase: Implication for the Existing …
G Garcia-Effron, S Lee, S Park, JD Cleary, DS Perlin
Antimicrobial agents and chemotherapy 53 (9), 3690-3699, 2009
Echinocandin Resistance in Candida
DS Perlin
Clinical Infectious Diseases 61 (suppl_6), S612-S617, 2015
Echinocandin resistance: an emerging clinical problem?
MC Arendrup, DS Perlin
Current opinion in infectious diseases 27 (6), 484-492, 2014
Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole
AM Nascimento, GH Goldman, S Park, SAE Marras, G Delmas, U Oza, ...
Antimicrobial agents and chemotherapy 47 (5), 1719-1726, 2003
Current perspectives on echinocandin class drugs
DS Perlin
Future microbiology 6 (4), 441-457, 2011
Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints
G Garcia-Effron, S Park, DS Perlin
Antimicrobial agents and chemotherapy 53 (1), 112-122, 2009
Mechanisms of echinocandin antifungal drug resistance
DS Perlin
Annals of the new York Academy of Sciences 1354 (1), 1-11, 2015
Assessing Resistance to the Echinocandin Antifungal Drug Caspofungin in Candida albicans by Profiling Mutations in FKS1
SV Balashov, S Park, DS Perlin
Antimicrobial agents and chemotherapy 50 (6), 2058-2063, 2006
Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance
KR Healey, Y Zhao, WB Perez, SR Lockhart, JD Sobel, D Farmakiotis, ...
Nature communications 7 (1), 11128, 2016
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