| Glioma stem cells promote radioresistance by preferential activation of the DNA damage response S Bao, Q Wu, RE McLendon, Y Hao, Q Shi, AB Hjelmeland, MW Dewhirst, ... nature 444 (7120), 756-760, 2006 | 7459 | 2006 |
| Bevacizumab plus irinotecan in recurrent glioblastoma multiforme JJ Vredenburgh, A Desjardins, JE Herndon, J Marcello, DA Reardon, ... Journal of clinical oncology 25 (30), 4722-4729, 2007 | 1722 | 2007 |
| Cancer stem cells in glioblastoma JD Lathia, SC Mack, EE Mulkearns-Hubert, CLL Valentim, JN Rich Genes & development 29 (12), 1203-1217, 2015 | 1698 | 2015 |
| Stem cell–like glioma cells promote tumor angiogenesis through vascular endothelial growth factor S Bao, Q Wu, S Sathornsumetee, Y Hao, Z Li, AB Hjelmeland, Q Shi, ... Cancer research 66 (16), 7843-7848, 2006 | 1644 | 2006 |
| Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells Z Li, S Bao, Q Wu, H Wang, C Eyler, S Sathornsumetee, Q Shi, Y Cao, ... Cancer cell 15 (6), 501-513, 2009 | 1531 | 2009 |
| Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma JJ Vredenburgh, A Desjardins, JE Herndon, JM Dowell, DA Reardon, ... Clinical cancer research 13 (4), 1253-1259, 2007 | 1288 | 2007 |
| Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth L Cheng, Z Huang, W Zhou, Q Wu, S Donnola, JK Liu, X Fang, AE Sloan, ... Cell 153 (1), 139-152, 2013 | 965 | 2013 |
| Survival of the fittest: cancer stem cells in therapeutic resistance and angiogenesis CE Eyler, JN Rich Journal of Clinical Oncology 26 (17), 2839-2845, 2008 | 946 | 2008 |
| The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype JM Heddleston, Z Li, RE McLendon, AB Hjelmeland, JN Rich Cell cycle 8 (20), 3274-3284, 2009 | 936 | 2009 |
| Making a tumour's bed: glioblastoma stem cells and the vascular niche RJ Gilbertson, JN Rich Nature Reviews Cancer 7 (10), 733-736, 2007 | 916 | 2007 |
| Phase II trial of gefitinib in recurrent glioblastoma JN Rich, DA Reardon, T Peery, JM Dowell, JA Quinn, KL Penne, ... Journal of Clinical Oncology 22 (1), 133-142, 2004 | 880 | 2004 |
| Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth W Zhou, SQ Ke, Z Huang, W Flavahan, X Fang, J Paul, L Wu, AE Sloan, ... Nature cell biology 17 (2), 170-182, 2015 | 861 | 2015 |
| Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells E Kim, M Kim, DH Woo, Y Shin, J Shin, N Chang, YT Oh, H Kim, J Rheey, ... Cancer cell 23 (6), 839-852, 2013 | 833 | 2013 |
| Integrin alpha 6 regulates glioblastoma stem cells JD Lathia, J Gallagher, JM Heddleston, J Wang, CE Eyler, J MacSwords, ... Cell stem cell 6 (5), 421-432, 2010 | 799 | 2010 |
| Notch promotes radioresistance of glioma stem cells J Wang, TP Wakeman, JD Lathia, AB Hjelmeland, XF Wang, RR White, ... Stem cells 28 (1), 17-28, 2010 | 783 | 2010 |
| Challenges to curing primary brain tumours K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ... Nature reviews Clinical oncology 16 (8), 509-520, 2019 | 747 | 2019 |
| Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway S Bao, G Ouyang, X Bai, Z Huang, C Ma, M Liu, R Shao, RM Anderson, ... Cancer cell 5 (4), 329-339, 2004 | 694 | 2004 |
| Cancer stem cells in radiation resistance JN Rich Cancer research 67 (19), 8980-8984, 2007 | 618 | 2007 |
| A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo CG Hubert, M Rivera, LC Spangler, Q Wu, SC Mack, BC Prager, M Couce, ... Cancer research 76 (8), 2465-2477, 2016 | 596 | 2016 |
| HIF induces human embryonic stem cell markers in cancer cells J Mathieu, Z Zhang, W Zhou, AJ Wang, JM Heddleston, CMA Pinna, ... Cancer research 71 (13), 4640-4652, 2011 | 596 | 2011 |
Justin D LathiaProfessor, Cleveland ClinicVerified email at ccf.org
