NeoPredPipe: high-throughput neoantigen prediction and recognition potential pipeline RO Schenck, E Lakatos, C Gatenbee, TA Graham, ARA Anderson BMC bioinformatics 20 (1), 1-6, 2019 | 113 | 2019 |
Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature, 1-10, 2022 | 109 | 2022 |
Evolutionary dynamics of neoantigens in growing tumors E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, L Zapata, ... Nature genetics 52 (10), 1057-1066, 2020 | 108 | 2020 |
Multivariate moment closure techniques for stochastic kinetic models E Lakatos, A Ale, PDW Kirk, MPH Stumpf The Journal of chemical physics 143 (9), 094107, 2015 | 87 | 2015 |
The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature, 1-11, 2022 | 80 | 2022 |
The mutational signatures of formalin fixation on the human genome Q Guo, E Lakatos, IA Bakir, K Curtius, TA Graham, V Mustonen Nature communications 13 (1), 1-14, 2022 | 59 | 2022 |
Transition state characteristics during cell differentiation RD Brackston, E Lakatos, MPH Stumpf PLoS computational biology 14 (9), e1006405, 2018 | 52 | 2018 |
Immune selection determines tumor antigenicity and influences response to checkpoint inhibitors L Zapata, G Caravagna, MJ Williams, E Lakatos, K AbdulJabbar, ... Nature Genetics 55 (3), 451-460, 2023 | 40 | 2023 |
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues C Gabbutt, RO Schenck, DJ Weisenberger, C Kimberley, A Berner, ... Nature biotechnology 40 (5), 720-730, 2022 | 39 | 2022 |
Immunosuppressive niche engineering at the onset of human colorectal cancer CD Gatenbee, AM Baker, RO Schenck, M Strobl, J West, MP Neves, ... Nature Communications 13 (1), 1798, 2022 | 33 | 2022 |
MEANS: python package for Moment Expansion Approximation, iNference and Simulation S Fan, Q Geissmann, E Lakatos, S Lukauskas, A Ale, AC Babtie, ... Bioinformatics 32 (18), 2863-2865, 2016 | 19 | 2016 |
The genomic landscape of 2,023 colorectal cancers AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... Nature 633 (8028), 127-136, 2024 | 18 | 2024 |
Control mechanisms for stochastic biochemical systems via computation of reachable sets E Lakatos, MPH Stumpf Royal Society open science 4 (8), 160790, 2017 | 10 | 2017 |
Stochastic analysis and control methods for molecular cell biology E Lakatos Imperial College London, 2017 | 9 | 2017 |
LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations E Lakatos, H Hockings, M Mossner, W Huang, M Lockley, TA Graham Iscience 24 (8), 2021 | 8 | 2021 |
Topology of interaction between titin and myosin thick filaments M Kellermayer, D Sziklai, Z Papp, B Decker, E Lakatos, Z Mártonfalvi Journal of structural biology 203 (1), 46-53, 2018 | 8 | 2018 |
Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer H Hockings, E Lakatos, W Huang, M Mossner, MA Khan, S Metcalf, ... bioRxiv, 2023.07. 21.549688, 2023 | 6 | 2023 |
Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... bioRxiv, 2022.11. 16.515599, 2022 | 6 | 2022 |
Protein degradation rate is the dominant mechanism accounting for the differences in protein abundance of basal p53 in a human breast and colorectal cancer cell line E Lakatos, A Salehi-Reyhani, M Barclay, MPH Stumpf, DR Klug PloS one 12 (5), e0177336, 2017 | 6 | 2017 |
Mutation Rate Evolution Drives Immune Escape in Mismatch Repair-Deficient Cancer H Kayhanian, P Barmpoutis, E Lakatos, W Cross, G Caravagna, L Zapata, ... bioRxiv, 2022.03. 06.482973, 2022 | 5 | 2022 |