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Tim Dierckx
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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes
JE Neggers, B Kwanten, T Dierckx, H Noguchi, A Voet, L Bral, K Minner, ...
Nature Communications 9 (1), 502, 2018
1102018
Inflammatory gene expression profile and defective interferon‐γ and granzyme K in natural killer cells from systemic juvenile idiopathic arthritis patients
K Put, J Vandenhaute, A Avau, A Van Nieuwenhuijze, E Brisse, T Dierckx, ...
Arthritis & Rheumatology 69 (1), 213-224, 2017
822017
Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC
N Conceição-Neto, W Deboutte, T Dierckx, K Machiels, J Wang, KC Yinda, ...
Gut 67 (8), 1558-1559, 2018
642018
Systems approach reveals nuclear factor erythroid 2-related factor 2/protein kinase R crosstalk in human cutaneous leishmaniasis
ÁC Vivarini, TC Calegari-Silva, AM Saliba, VS Boaventura, ...
Frontiers in immunology 8, 1127, 2017
432017
ISG15-induced IL-10 is a novel anti-inflammatory myeloid axis disrupted during active tuberculosis
PF Dos Santos, J Van Weyenbergh, M Delgobo, D Oliveira Patricio, ...
The Journal of Immunology 200 (4), 1434-1442, 2018
392018
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
M Delgobo, DAGB Mendes, E Kozlova, EL Rocha, GF Rodrigues-Luiz, ...
elife 8, e47013, 2019
382019
GlycA, a nuclear magnetic resonance spectroscopy measure for protein glycosylation, is a viable biomarker for disease activity in IBD
T Dierckx, B Verstockt, S Vermeire, J van Weyenbergh
Journal of Crohn's and Colitis 13 (3), 389-394, 2019
382019
Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection
KF Fukutani, CM Nascimento-Carvalho, W Van der Gucht, E Wollants, ...
Journal of Clinical Virology 69, 190-196, 2015
262015
IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients
T Dierckx, R Khouri, SM Menezes, D Decanine, L Farre, A Bittencourt, ...
Blood cancer journal 7 (1), e519-e519, 2017
242017
Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated …
FE Leal, SM Menezes, EAS Costa, PM Brailey, L Gama, AC Segurado, ...
Frontiers in microbiology 9, 985, 2018
212018
The metabolic fingerprint of COVID-19 severity
T Dierckx, J Van Elslande, H Salmela, B Decru, E Wauters, J Gunst, ...
MedRxiv, 2020.11. 09.20228221, 2020
172020
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation
SM Menezes, FE Leal, T Dierckx, R Khouri, D Decanine, G Silva-Santos, ...
Frontiers in immunology 8, 97, 2017
172017
Detection of natural resistance-associated substitutions by ion semiconductor technology in HCV1b positive, direct-acting antiviral agents-naïve patients
N Marascio, G Pavia, A Strazzulla, T Dierckx, L Cuypers, B Vrancken, ...
International Journal of Molecular Sciences 17 (9), 1416, 2016
172016
Decreased RORC expression and downstream signaling in HTLV‐1‐associated adult T‐cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for …
K Subramanian, T Dierckx, R Khouri, SM Menezes, H Kagdi, GP Taylor, ...
International Journal of Cancer 144 (7), 1664-1675, 2019
152019
A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients
R Khouri, G Silva-Santos, T Dierckx, SM Menezes, D Decanine, K Theys, ...
Oncoimmunology 7 (5), e1426423, 2018
152018
In situ Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection
KF Fukutani, CM Nascimento-Carvalho, ML Bouzas, JR Oliveira, A Barral, ...
Frontiers in Microbiology 9, 2475, 2018
132018
Urinary peptides as potential non-invasive biomarkers for Lupus Nephritis: results of the Peptidu-LUP Study
M Tailliar, JP Schanstra, T Dierckx, B Breuil, G Hanouna, N Charles, ...
Journal of Clinical Medicine 10 (8), 1690, 2021
122021
enAsCas12a enables CRISPR-directed evolution to screen for functional drug resistance mutations in sequences inaccessible to SpCas9
JE Neggers, M Jacquemyn, T Dierckx, BP Kleinstiver, HJ Thibaut, ...
Molecular Therapy 29 (1), 208-224, 2021
112021
Serum GlycA level is elevated in active systemic lupus erythematosus and correlates to disease activity and lupus nephritis severity
T Dierckx, L Chiche, L Daniel, B Lauwerys, J Van Weyenbergh, ...
Journal of clinical medicine 9 (4), 970, 2020
112020
XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis
E Boons, TC Nogueira, T Dierckx, SM Menezes, M Jacquemyn, S Tamir, ...
Blood cancer journal 11 (2), 27, 2021
72021
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Articles 1–20