Patricia McDonald
Patricia McDonald
Associate Professor, Moffitt Cancer Center
Verified email at
Cited by
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β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3
PH McDonald, CW Chow, WE Miller, SA Laporte, ME Field, FT Lin, ...
Science 290 (5496), 1574-1577, 2000
Regulation of receptor fate by ubiquitination of activated β2-adrenergic receptor and β-arrestin
SK Shenoy, PH McDonald, TA Kohout, RJ Lefkowitz
Science 294 (5545), 1307-1313, 2001
Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary β2-adrenergic receptor gene delivery
JP Maurice, JA Hata, AS Shah, DC White, PH McDonald, PC Dolber, ...
The Journal of clinical investigation 104 (1), 21-29, 1999
Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
SA Akhter, CA Skaer, AP Kypson, PH McDonald, KC Peppel, DD Glower, ...
Proceedings of the National Academy of Sciences 94 (22), 12100-12105, 1997
Structural mechanism of ligand activation in human calcium-sensing receptor
Y Geng, L Mosyak, I Kurinov, H Zuo, E Sturchler, TC Cheng, ...
Elife 5, e13662, 2016
G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization
K Peppel, I Boekhoff, P McDonald, H Breer, MG Caron, RJ Lefkowitz
Journal of Biological Chemistry 272 (41), 25425-25428, 1997
Identification of NSF as a β-arrestin1-binding protein: implications for β2-adrenergic receptor regulation
PH McDonald, NL Cote, FT Lin, RT Premont, JA Pitcher, RJ Lefkowitz
Journal of Biological Chemistry 274 (16), 10677-10680, 1999
GPCRs: Emerging anti-cancer drug targets
AN Gutierrez, PH McDonald
Cellular signalling 41, 65-74, 2018
Identification of a motif in the carboxyl terminus of β-arrestin2 responsible for activation of JNK3
WE Miller, PH McDonald, SF Cai, ME Field, RJ Davis, RJ Lefkowitz
Journal of Biological Chemistry 276 (30), 27770-27777, 2001
βArrestins: new roles in regulating heptahelical receptors' functions
PH McDonald, RJ Lefkowitz
Cellular signalling 13 (10), 683-689, 2001
Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway
AS Pachori, A Smith, P McDonald, L Zhang, VJ Dzau, LG Melo
Journal of molecular and cellular cardiology 43 (5), 580-592, 2007
Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects
H Zhang, E Sturchler, J Zhu, A Nieto, PA Cistrone, J Xie, LL He, K Yea, ...
Nature Communications 6 (1), 8918, 2015
Augmentation of Cardiac Contractility Mediated by the Human β3-Adrenergic Receptor Overexpressed in the Hearts of Transgenic Mice
TA Kohout, H Takaoka, PH McDonald, SJ Perry, L Mao, RJ Lefkowitz, ...
Circulation 104 (20), 2485-2491, 2001
The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced β-arrestin 2 interaction
MM Berglund, DA Schober, MA Statnick, PH McDonald, DR Gehlert
Journal of Pharmacology and Experimental Therapeutics 306 (1), 147-156, 2003
Adenovirus-mediated gene transfer of the β2-adrenergic receptor to donor hearts enhances cardiac function
AP Kypson, SC Hendrickson, SA Akhter, K Wilson, PH McDonald, RE Lilly, ...
Gene Therapy 6 (7), 1298-1304, 1999
Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening
SP Brothers, SA Saldanha, TP Spicer, M Cameron, BA Mercer, P Chase, ...
Molecular pharmacology 77 (1), 46-57, 2010
Melanocortin‐3 receptors are involved in adaptation to restricted feeding
K Begriche, OJ Marston, J Rossi, LK Burke, P McDonald, LK Heisler, ...
Genes, Brain and Behavior 11 (3), 291-302, 2012
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison
S Dabul, A Bathgate-Siryk, TR Valero, M Jafferjee, E Sturchler, ...
Scientific reports 5 (1), 8116, 2015
Melanocortin-3 receptors and metabolic homeostasis
K Begriche, C Girardet, P McDonald, AA Butler
Progress in molecular biology and translational science 114, 109-146, 2013
Structural basis for auxiliary subunit KCTD16 regulation of the GABAB receptor
H Zuo, I Glaaser, Y Zhao, I Kurinov, L Mosyak, H Wang, J Liu, J Park, ...
Proceedings of the National Academy of Sciences 116 (17), 8370-8379, 2019
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