| Advances in the delivery of RNA therapeutics: from concept to clinical reality JC Kaczmarek, PS Kowalski, DG Anderson Genome medicine 9, 1-16, 2017 | 636 | 2017 |
| Polymer–lipid nanoparticles for systemic delivery of mRNA to the lungs JC Kaczmarek, AK Patel, KJ Kauffman, OS Fenton, MJ Webber, ... Angewandte Chemie 128 (44), 14012-14016, 2016 | 291 | 2016 |
| Inhaled nanoformulated mRNA polyplexes for protein production in lung epithelium AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ... Advanced Materials 31 (8), 1805116, 2019 | 281 | 2019 |
| Synthesis and biological evaluation of ionizable lipid materials for the in vivo delivery of messenger RNA to B lymphocytes OS Fenton, KJ Kauffman, JC Kaczmarek, RL McClellan, S Jhunjhunwala, ... Advanced Materials 29 (33), 1606944, 2017 | 195 | 2017 |
| Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo KJ Kauffman, FF Mir, S Jhunjhunwala, JC Kaczmarek, JE Hurtado, ... Biomaterials 109, 78-87, 2016 | 175 | 2016 |
| Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells JC Kaczmarek, KJ Kauffman, OS Fenton, K Sadtler, AK Patel, ... Nano letters 18 (10), 6449-6454, 2018 | 167 | 2018 |
| Rapid, single-cell analysis and discovery of vectored mRNA transfection in vivo with a loxP-flanked tdTomato reporter mouse KJ Kauffman, MA Oberli, JR Dorkin, JE Hurtado, JC Kaczmarek, ... Molecular therapy-Nucleic acids 10, 55-63, 2018 | 78 | 2018 |
| Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs OS Fenton, KJ Kauffman, RL McClellan, JC Kaczmarek, MD Zeng, ... Angewandte Chemie International Edition 57 (41), 13582-13586, 2018 | 73 | 2018 |
| Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles JC Kaczmarek, AK Patel, LH Rhym, UC Palmiero, B Bhat, MW Heartlein, ... Biomaterials 275, 120966, 2021 | 67 | 2021 |
| Poly(β‐amino ester)‐co‐poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo U Capasso Palmiero, JC Kaczmarek, OS Fenton, DG Anderson Advanced Healthcare Materials 7 (14), 1800249, 2018 | 67 | 2018 |
| Cancer nanotherapeutics in clinical trials AKR Lytton-Jean, KJ Kauffman, JC Kaczmarek, R Langer Nanotechnology-Based Precision Tools for the Detection and Treatment of …, 2015 | 50 | 2015 |
| Adjusting biomaterial composition to achieve controlled multiple-day release of dexamethasone from an extended-wear silicone hydrogel contact lens JC Kaczmarek, A Tieppo, CJ White, ME Byrne Journal of Biomaterials Science, Polymer Edition 25 (1), 88-100, 2014 | 40 | 2014 |
| Poly (beta-amino esters) and uses thereof DG Anderson, KJ Kauffman, JC Kaczmarek, AK Patel US Patent 11,464,860, 2022 | 3 | 2022 |
| Gene delivery carrier UC Palmiero, JC Kaczmarek, DG Anderson, D Moscatelli US Patent App. 17/347,791, 2021 | 1 | 2021 |
| Gene delivery carrier UC Palmiero, JC Kaczmarek, DG Anderson, D Moscatelli US Patent 11,041,069, 2021 | 1 | 2021 |
| Gene Delivery: Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium (Adv. Mater. 8/2019) AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ... Advanced Materials 31 (8), 1970053, 2019 | 1 | 2019 |
| Poly (beta-amino esters) and uses thereof DG Anderson, KJ Kauffman, JC Kaczmarek, AK Patel US Patent 11,696,953, 2023 | | 2023 |
| Polymer-lipids and compositions JC Kaczmarek, DG Anderson, LH Rhym, KJ Kauffman, AK Patel US Patent 11,608,412, 2023 | | 2023 |
| Development of polymer-lipid nanoparticles for potent mRNA delivery to the lung JC Kaczmarek Massachusetts Institute of Technology, 2018 | | 2018 |
| Gene delivery carrier D Moscatelli, U Capasso Palmiero, D Anderson, J Kaczmarek | | 2017 |
Daniel G. AndersonMassachusetts Institute of TechnologyVerified email at mit.edu
