| Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification BS Clark, GL Stein-O’Brien, F Shiau, GH Cannon, E Davis-Marcisak, ... Neuron 102 (6), 1111-1126. e5, 2019 | 372 | 2019 |
| Enter the matrix: factorization uncovers knowledge from omics GL Stein-O’Brien, R Arora, AC Culhane, AV Favorov, LX Garmire, ... Trends in Genetics 34 (10), 790-805, 2018 | 235 | 2018 |
| Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson, A Kallman, S Zhong, ... Developmental cell 53 (4), 473-491. e9, 2020 | 215 | 2020 |
| Neoadjuvant cabozantinib and nivolumab converts locally advanced HCC into resectable disease with enhanced antitumor immunity. WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ... Nature cancer 2 (9), 891-903, 2021 | 150 | 2021 |
| Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species GL Stein-O’Brien, BS Clark, T Sherman, C Zibetti, Q Hu, R Sealfon, S Liu, ... Cell systems 8 (5), 395-411. e8, 2019 | 144 | 2019 |
| Aging-like spontaneous epigenetic silencing facilitates Wnt activation, stemness, and BrafV600E-induced tumorigenesis Y Tao, B Kang, DA Petkovich, YR Bhandari, J In, G Stein-O'Brien, X Kong, ... Cancer cell 35 (2), 315-328. e6, 2019 | 137 | 2019 |
| Epigenetic regulation of gene expression in cancer: techniques, resources and analysis LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ... Briefings in functional genomics 17 (1), 49-63, 2018 | 131 | 2018 |
| Psychedelics reopen the social reward learning critical period R Nardou, E Sawyer, YJ Song, M Wilkinson, Y Padovan-Hernandez, ... Nature 618 (7966), 790-798, 2023 | 102 | 2023 |
| From bench to bedside: Single-cell analysis for cancer immunotherapy EF Davis-Marcisak, A Deshpande, GL Stein-O’Brien, WJ Ho, D Laheru, ... Cancer cell 39 (8), 1062-1080, 2021 | 83 | 2021 |
| Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ... Nature Cancer 2 (9), 891-903, 2021 | 67 | 2021 |
| Universal prediction of cell-cycle position using transfer learning SC Zheng, G Stein-O’Brien, JJ Augustin, J Slosberg, GA Carosso, B Winer, ... Genome biology 23 (1), 41, 2022 | 63 | 2022 |
| projectR: an R/Bioconductor package for transfer learning via PCA, NMF, correlation and clustering G Sharma, C Colantuoni, LA Goff, EJ Fertig, G Stein-O’Brien Bioinformatics 36 (11), 3592-3593, 2020 | 61 | 2020 |
| Parallel social information processing circuits are differentially impacted in autism EM Lewis, GL Stein-O’Brien, AV Patino, R Nardou, CD Grossman, ... Neuron 108 (4), 659-675. e6, 2020 | 59 | 2020 |
| PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF GL Stein-O’Brien, JL Carey, WS Lee, M Considine, AV Favorov, E Flam, ... Bioinformatics 33 (12), 1892-1894, 2017 | 57 | 2017 |
| Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution JS Heng, A Rattner, GL Stein-O’Brien, BL Winer, BW Jones, HJ Vernon, ... Proceedings of the National Academy of Sciences 116 (18), 9103-9114, 2019 | 55 | 2019 |
| Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation GJ Sun, Y Zhou, S Ito, MA Bonaguidi, G Stein-O'Brien, NK Kawasaki, ... Nature neuroscience 18 (12), 1722-1724, 2015 | 53 | 2015 |
| Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing JS Heng, SF Hackett, GL Stein-O’Brien, BL Winer, J Williams, LA Goff, ... Proceedings of the National Academy of Sciences 116 (52), 26734-26744, 2019 | 47 | 2019 |
| Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance G Stein-O’Brien, LT Kagohara, S Li, M Thakar, R Ranaweera, H Ozawa, ... Genome medicine 10, 1-22, 2018 | 40 | 2018 |
| Differential variation analysis enables detection of tumor heterogeneity using single-cell RNA-sequencing data EF Davis-Marcisak, TD Sherman, P Orugunta, GL Stein-O'Brien, ... Cancer research 79 (19), 5102-5112, 2019 | 38 | 2019 |
| Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways WJ Ho, R Erbe, L Danilova, Z Phyo, E Bigelow, G Stein-O’Brien, ... Genome biology 22 (1), 154, 2021 | 36 | 2021 |
Elana J FertigProfessor of Oncology Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive CancerVerified email at jhmi.edu
