Genevieve Stein-O'Brien
Genevieve Stein-O'Brien
Assistant Professor, Department of Neuroscience, Johns Hopkins University
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Cited by
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Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification
BS Clark, GL Stein-O’Brien, F Shiau, GH Cannon, E Davis-Marcisak, ...
Neuron 102 (6), 1111-1126. e5, 2019
Enter the matrix: factorization uncovers knowledge from omics
GL Stein-O’Brien, R Arora, AC Culhane, AV Favorov, LX Garmire, ...
Trends in Genetics 34 (10), 790-805, 2018
Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development
Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson, A Kallman, S Zhong, ...
Developmental cell 53 (4), 473-491. e9, 2020
Decomposing cell identity for transfer learning across cellular measurements, platforms, tissues, and species
GL Stein-O’Brien, BS Clark, T Sherman, C Zibetti, Q Hu, R Sealfon, S Liu, ...
Cell systems 8 (5), 395-411. e8, 2019
Aging-like spontaneous epigenetic silencing facilitates Wnt activation, stemness, and BrafV600E-induced tumorigenesis
Y Tao, B Kang, DA Petkovich, YR Bhandari, J In, G Stein-O'Brien, X Kong, ...
Cancer cell 35 (2), 315-328. e6, 2019
Neoadjuvant cabozantinib and nivolumab converts locally advanced HCC into resectable disease with enhanced antitumor immunity.
WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ...
Nature cancer 2 (9), 891-903, 2021
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis
LT Kagohara, GL Stein-O’Brien, D Kelley, E Flam, HC Wick, LV Danilova, ...
Briefings in functional genomics 17 (1), 49-63, 2018
From bench to bedside: Single-cell analysis for cancer immunotherapy
EF Davis-Marcisak, A Deshpande, GL Stein-O’Brien, WJ Ho, D Laheru, ...
Cancer cell 39 (8), 1062-1080, 2021
Psychedelics reopen the social reward learning critical period
R Nardou, E Sawyer, YJ Song, M Wilkinson, Y Padovan-Hernandez, ...
Nature 618 (7966), 790-798, 2023
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity
WJ Ho, Q Zhu, J Durham, A Popovic, S Xavier, J Leatherman, A Mohan, ...
Nature Cancer 2 (9), 891-903, 2021
Parallel social information processing circuits are differentially impacted in autism
EM Lewis, GL Stein-O’Brien, AV Patino, R Nardou, CD Grossman, ...
Neuron 108 (4), 659-675. e6, 2020
Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation
GJ Sun, Y Zhou, S Ito, MA Bonaguidi, G Stein-O'Brien, NK Kawasaki, ...
Nature neuroscience 18 (12), 1722-1724, 2015
Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution
JS Heng, A Rattner, GL Stein-O’Brien, BL Winer, BW Jones, HJ Vernon, ...
Proceedings of the National Academy of Sciences 116 (18), 9103-9114, 2019
PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF
GL Stein-O’Brien, JL Carey, WS Lee, M Considine, AV Favorov, E Flam, ...
Bioinformatics 33 (12), 1892-1894, 2017
projectR: an R/Bioconductor package for transfer learning via PCA, NMF, correlation and clustering
G Sharma, C Colantuoni, LA Goff, EJ Fertig, G Stein-O’Brien
Bioinformatics 36 (11), 3592-3593, 2020
Universal prediction of cell-cycle position using transfer learning
SC Zheng, G Stein-O’Brien, JJ Augustin, J Slosberg, GA Carosso, B Winer, ...
Genome biology 23 (1), 41, 2022
Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing
JS Heng, SF Hackett, GL Stein-O’Brien, BL Winer, J Williams, LA Goff, ...
Proceedings of the National Academy of Sciences 116 (52), 26734-26744, 2019
Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance
G Stein-O’Brien, LT Kagohara, S Li, M Thakar, R Ranaweera, H Ozawa, ...
Genome medicine 10, 1-22, 2018
Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways
WJ Ho, R Erbe, L Danilova, Z Phyo, E Bigelow, G Stein-O’Brien, ...
Genome biology 22 (1), 154, 2021
Differential variation analysis enables detection of tumor heterogeneity using single-cell RNA-sequencing data
EF Davis-Marcisak, TD Sherman, P Orugunta, GL Stein-O'Brien, ...
Cancer research 79 (19), 5102-5112, 2019
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