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Amanda Heslegrave
Amanda Heslegrave
Senior Research Associate University College London
Overená e-mailová adresa na: ucl.ac.uk
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Citované v
Citované v
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Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
A Heslegrave, W Heywood, R Paterson, N Magdalinou, J Svensson, ...
Molecular neurodegeneration 11, 1-7, 2016
2882016
Molecular biomarkers of Alzheimer's disease: progress and prospects
T Lashley, JM Schott, P Weston, CE Murray, H Wellington, A Keshavan, ...
Disease models & mechanisms 11 (5), dmm031781, 2018
2122018
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ...
Science translational medicine 11 (505), eaau2291, 2019
2092019
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo
R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ...
EMBO molecular medicine 10 (1), 22-31, 2018
2082018
Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for …
BJ Neth, A Mintz, C Whitlow, Y Jung, KS Sai, TC Register, D Kellar, ...
Neurobiology of aging 86, 54-63, 2020
1672020
Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay
WE Heywood, D Galimberti, E Bliss, E Sirka, RW Paterson, ...
Molecular neurodegeneration 10, 1-16, 2015
1602015
Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease
LM Byrne, FB Rodrigues, EB Johnson, PA Wijeratne, E De Vita, ...
Science translational medicine 10 (458), eaat7108, 2018
1492018
Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis
P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ...
Cell Reports 24 (9), 2300-2311, 2018
1432018
Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia
C Heller, MS Foiani, K Moore, R Convery, M Bocchetta, M Neason, ...
Journal of Neurology, Neurosurgery & Psychiatry 91 (3), 263-270, 2020
1322020
Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta
C Arber, J Toombs, C Lovejoy, NS Ryan, RW Paterson, N Willumsen, ...
Molecular Psychiatry 25 (11), 2919-2931, 2020
1272020
Diagnosis across the spectrum of progressive supranuclear palsy and corticobasal syndrome
E Jabbari, N Holland, V Chelban, PS Jones, R Lamb, C Rawlinson, T Guo, ...
JAMA neurology 77 (3), 377-387, 2020
1262020
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase
N Stahmann, A Woods, K Spengler, A Heslegrave, R Bauer, S Krause, ...
Journal of biological chemistry 285 (14), 10638-10652, 2010
1192010
Population-based blood screening for preclinical Alzheimer’s disease in a British birth cohort at age 70
A Keshavan, J Pannee, TK Karikari, JL Rodriguez, NJ Ashton, ...
Brain 144 (2), 434-449, 2021
1082021
Cerebrospinal fluid in the differential diagnosis of Alzheimer’s disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic
RW Paterson, CF Slattery, T Poole, JM Nicholas, NK Magdalinou, ...
Alzheimer's research & therapy 10, 1-11, 2018
1062018
Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study
A O’Connor, TK Karikari, T Poole, NJ Ashton, J Lantero Rodriguez, ...
Molecular psychiatry 26 (10), 5967-5976, 2021
962021
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury
NSN Graham, KA Zimmerman, F Moro, A Heslegrave, SA Maillard, ...
Science translational medicine 13 (613), eabg9922, 2021
952021
Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone
A Öhrfelt, M Axelsson, C Malmeström, L Novakova, A Heslegrave, ...
Multiple Sclerosis Journal 22 (12), 1587-1595, 2016
932016
Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and …
ML Alosco, Y Tripodis, NG Fritts, A Heslegrave, CM Baugh, S Conneely, ...
Alzheimer's & Dementia 14 (9), 1159-1170, 2018
912018
Laboratory biomarkers associated with COVID-19 severity and management
S Keddie, O Ziff, MKL Chou, RL Taylor, A Heslegrave, E Garr, ...
Clinical immunology 221, 108614, 2020
892020
Nitric oxide‐dependent damage to neuronal mitochondria involves the NMDA receptor
VC Stewart, AJ Heslegrave, GC Brown, JB Clark, SJR Heales
European Journal of Neuroscience 15 (3), 458-464, 2002
892002
Systém momentálne nemôže vykonať operáciu. Skúste to neskôr.
Články 1–20