| Therapeutic vesicular nanoreactors with tumor‐specific activation and self‐destruction for synergistic tumor ablation J Li, A Dirisala, Z Ge, Y Wang, W Yin, W Ke, K Toh, J Xie, Y Matsumoto, ... Angewandte Chemie 129 (45), 14213-14218, 2017 | 211 | 2017 |
| Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors Z Ge, Q Chen, K Osada, X Liu, TA Tockary, S Uchida, A Dirisala, T Ishii, ... Biomaterials 35 (10), 3416-3426, 2014 | 137 | 2014 |
| Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers TA Tockary, K Osada, Q Chen, K Machitani, A Dirisala, S Uchida, ... Macromolecules 46 (16), 6585-6592, 2013 | 120 | 2013 |
| Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium D Gonzalez-Carter, X Liu, TA Tockary, A Dirisala, K Toh, Y Anraku, ... Proceedings of the National Academy of Sciences 117 (32), 19141-19150, 2020 | 99 | 2020 |
| Secondary‐Structure‐Driven Self‐Assembly of Reactive Polypept (o) ides: Controlling Size, Shape, and Function of Core Cross‐Linked Nanostructures K Klinker, O Schäfer, D Huesmann, T Bauer, L Capelôa, L Braun, ... Angewandte Chemie International Edition 56 (32), 9608-9613, 2017 | 83 | 2017 |
| Dual-sensitive nanomicelles enhancing systemic delivery of therapeutically active antibodies specifically into the brain J Xie, D Gonzalez-Carter, TA Tockary, N Nakamura, Y Xue, M Nakakido, ... ACS nano 14 (6), 6729-6742, 2020 | 75 | 2020 |
| Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors A Dirisala, K Osada, Q Chen, TA Tockary, K Machitani, S Osawa, X Liu, ... Biomaterials 35 (20), 5359-5368, 2014 | 75 | 2014 |
| Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain S Abbasi, S Uchida, K Toh, TA Tockary, A Dirisala, K Hayashi, ... Journal of Controlled Release 332, 260-268, 2021 | 74 | 2021 |
| Ternary polyplex micelles with PEG shells and intermediate barrier to complexed DNA cores for efficient systemic gene delivery J Li, Q Chen, Z Zha, H Li, K Toh, A Dirisala, Y Matsumoto, K Osada, ... Journal of Controlled Release 209, 77-87, 2015 | 71 | 2015 |
| Stealth and pseudo-stealth nanocarriers P Wen, W Ke, A Dirisala, K Toh, M Tanaka, J Li Advanced drug delivery reviews 198, 114895, 2023 | 69 | 2023 |
| Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability A Dirisala, S Uchida, TA Tockary, N Yoshinaga, J Li, S Osawa, L Gorantla, ... Journal of Drug Targeting 27 (5-6), 670-680, 2019 | 68 | 2019 |
| Effect of shear stress on structure and function of polyplex micelles from poly (ethylene glycol)-poly (l-lysine) block copolymers as systemic gene delivery carrier KM Takeda, Y Yamasaki, A Dirisala, S Ikeda, TA Tockary, K Toh, K Osada, ... Biomaterials 126, 31-38, 2017 | 64 | 2017 |
| Polyplex micelles with double-protective compartments of hydrophilic shell and thermoswitchable palisade of poly (oxazoline)-based block copolymers for promoted gene transfection S Osawa, K Osada, S Hiki, A Dirisala, T Ishii, K Kataoka Biomacromolecules 17 (1), 354-361, 2016 | 64 | 2016 |
| Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting Q Chen, K Osada, Z Ge, S Uchida, TA Tockary, A Dirisala, A Matsui, K Toh, ... Biomaterials 113, 253-265, 2017 | 61 | 2017 |
| Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity F Perche, Y Yi, L Hespel, P Mi, A Dirisala, H Cabral, K Miyata, K Kataoka Biomaterials 90, 62-71, 2016 | 56 | 2016 |
| Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines A Dirisala, S Uchida, K Toh, J Li, S Osawa, TA Tockary, X Liu, S Abbasi, ... Science Advances 6 (26), eabb8133, 2020 | 55 | 2020 |
| A nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using cross-linked polyion complex micelles bearing antibody fragments S Florinas, M Liu, R Fleming, L Van Vlerken-Ysla, J Ayriss, R Gilbreth, ... Biomacromolecules 17 (5), 1818-1833, 2016 | 50 | 2016 |
| Effective mRNA Protection by Poly(l‐ornithine) Synergizes with Endosomal Escape Functionality of a Charge‐Conversion Polymer toward Maximizing mRNA … A Dirisala, S Uchida, J Li, JFR Van Guyse, K Hayashi, SVC Vummaleti, ... Macromolecular rapid communications 43 (12), 2100754, 2022 | 49 | 2022 |
| Poly (ethylene glycol) crowding as critical factor to determine pDNA packaging scheme into polyplex micelles for enhanced gene expression KM Takeda, K Osada, TA Tockary, A Dirisala, Q Chen, K Kataoka Biomacromolecules 18 (1), 36-43, 2017 | 47 | 2017 |
| Enzymatically Transformable Polymersome‐Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer J Li, Z Ge, K Toh, X Liu, A Dirisala, W Ke, P Wen, H Zhou, Z Wang, S Xiao, ... Advanced Materials 33 (49), 2105254, 2021 | 44 | 2021 |
