| Inositol phosphates are assembly co-factors for HIV-1 RA Dick, KK Zadrozny, C Xu, FKM Schur, TD Lyddon, CL Ricana, ... Nature 560 (7719), 509-512, 2018 | 208 | 2018 |
| FEZ1 is recruited to a conserved cofactor site on capsid to promote HIV-1 trafficking PT Huang, BJ Summers, C Xu, JR Perilla, V Malikov, MH Naghavi, ... Cell reports 28 (9), 2373-2385. e7, 2019 | 67 | 2019 |
| Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations CM Quinn, M Wang, MP Fritz, B Runge, J Ahn, C Xu, JR Perilla, ... Proceedings of the National Academy of Sciences 115 (45), 11519-11524, 2018 | 58 | 2018 |
| Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis C Xu, DK Fischer, S Rankovic, W Li, RA Dick, B Runge, R Zadorozhnyi, ... PLoS biology 18 (12), e3001015, 2020 | 48 | 2020 |
| MxB restricts HIV-1 by targeting the tri-hexamer interface of the viral capsid SS Smaga, C Xu, BJ Summers, KM Digianantonio, JR Perilla, Y Xiong Structure 27 (8), 1234-1245. e5, 2019 | 46 | 2019 |
| Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly RA Dick, C Xu, DR Morado, V Kravchuk, CL Ricana, TD Lyddon, ... Plos Pathogens 16 (1), e1008277, 2020 | 44 | 2020 |
| Structure of native HIV-1 cores and their interactions with IP6 and CypA T Ni, Y Zhu, Z Yang, C Xu, Y Chaban, T Nesterova, J Ning, T Böcking, ... Science Advances 7 (47), eabj5715, 2021 | 21 | 2021 |
| Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation ZA Hing, JS Walker, EC Whipp, L Brinton, M Cannon, P Zhang, S Sher, ... Nature Communications 14 (1), 97, 2023 | 13 | 2023 |
| Molecular determinants of Ebola nucleocapsid stability from molecular dynamics simulations C Xu, N Katyal, T Nesterova, JR Perilla The Journal of Chemical Physics 153 (15), 2020 | 12 | 2020 |
| The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores Q Shen, S Kumari, C Xu, S Jang, J Shi, RC Burdick, L Levintov, Q Xiong, ... Proceedings of the National Academy of Sciences 120 (13), e2202815120, 2023 | 9 | 2023 |
| Structural basis of HIV-1 maturation inhibitor binding and activity S Sarkar, KK Zadrozny, R Zadorozhnyi, RW Russell, CM Quinn, ... Nature Communications 14 (1), 1237, 2023 | 8 | 2023 |
| Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode J Kraus, RW Russell, E Kudryashova, C Xu, N Katyal, JR Perilla, ... Nature Communications 13 (1), 2114, 2022 | 8 | 2022 |
| HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration M Balasubramaniam, BO Davids, A Bryer, C Xu, S Thapa, J Shi, C Aiken, ... PNAS nexus 1 (2), pgac064, 2022 | 7 | 2022 |
| A DNA-origami nuclear pore mimic reveals nuclear entry mechanisms of HIV-1 capsid Q Shen, C Xu, S Jang, Q Xiong, SC Devarkar, T Tian, GJ Bedwell, ... bioRxiv, 2020.08. 10.245522, 2020 | 6 | 2020 |
| FEZ1 is recruited to a conserved cofactor site on capsid to promote HIV-1 trafficking. Cell Rep 28: 2373–2385. e7 PT Huang, BJ Summers, C Xu, JR Perilla, V Malikov, MH Naghavi, ... | 5 | 2019 |
| Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization AT Gres, KA Kirby, WM McFadden, H Du, D Liu, C Xu, AJ Bryer, JR Perilla, ... Nature Communications 14 (1), 5614, 2023 | 3 | 2023 |
| Author Correction: Inositol phosphates are assembly co-factors for HIV-1 RA Dick, KK Zadrozny, C Xu, FKM Schur, TD Lyddon, CL Ricana, ... Nature 563 (7731), E22, 2018 | 3 | 2018 |
| Unsupervised Refinement of Protein Structures AJ Bryer, JS Rey, C Xu, JA Hadden-Perilla, JR Perilla | | 2023 |
| Large scale all-atom molecular dynamics simulations of mutant CA tubes provide insights on cytotoxic T-lymphocyte-mediated HIV-1 restriction AJ Bryer, M Balasubramaniam, S Thapa, BO Davids, C Xu, J Shi, C Aiken, ... Biophysical Journal 121 (3), 321a, 2022 | | 2022 |
| Equilibrium dynamics of the pre-and post-cleavage regions of SP1 are separately shifted by the HIV-1 maturation inhibitor Bevirimat C Xu, JR Perilla bioRxiv, 2022.02. 05.479246, 2022 | | 2022 |
Juan R. PerillaAssociate Professor of Chemistry and Biochemistry, University of DelawareVerified email at udel.edu
