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Kevin Harlen
Kevin Harlen
Research Fellow in Genetics, Harvard University
Verified email at hms.harvard.edu
Title
Cited by
Cited by
Year
The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain
KM Harlen, LS Churchman
Nature reviews Molecular cell biology 18 (4), 263-273, 2017
4542017
The ferritin superfamily: Supramolecular templates for materials synthesis
M Uchida, S Kang, C Reichhardt, K Harlen, T Douglas
Biochimica et Biophysica Acta (BBA)-General Subjects 1800 (8), 834-845, 2010
2842010
Comprehensive RNA polymerase II interactomes reveal distinct and varied roles for each phospho-CTD residue
KM Harlen, KL Trotta, EE Smith, MM Mosaheb, SM Fuchs, LS Churchman
Cell reports 15 (10), 2147-2158, 2016
1572016
Subgenic Pol II interactomes identify region‐specific transcription elongation regulators
KM Harlen, LS Churchman
Molecular Systems Biology 13 (1), 900, 2017
432017
Mechanism of membrane permeation induced by synthetic β-hairpin peptides
K Gupta, H Jang, K Harlen, A Puri, R Nussinov, JP Schneider, ...
Biophysical journal 105 (9), 2093-2103, 2013
432013
Cell-cycle modulation of transcription termination factor Sen1
HE Mischo, Y Chun, KM Harlen, BM Smalec, S Dhir, LS Churchman, ...
Molecular cell 70 (2), 312-326. e7, 2018
242018
Transcription elongation is finely tuned by dozens of regulatory factors
M Couvillion, KM Harlen, KC Lachance, KL Trotta, E Smith, C Brion, ...
Elife 11, e78944, 2022
102022
Live-cell assays for cell stress responses reveal new patterns of cell signaling caused by mutations in rhodopsin, α-synuclein and TDP-43
KM Harlen, EC Roush, JE Clayton, S Martinka, TE Hughes
Frontiers in Cellular Neuroscience 13, 535, 2019
72019
Neurodegenerative disease and cAMP signaling dynamics
E Roush, K Harlen, M Hendrickson, TE Hughes
Biophysical Journal 118 (3), 456a, 2020
22020
Interactome Dynamics of the Transcription Elongation Complex Revealed by Quantitative Proteomics
K Harlen, S Churchman
The FASEB Journal 29, 562.3, 2015
22015
Dynamics of transcription elongation are finely tuned by dozens of regulatory factors
M Couvillion, KM Harlen, KC Lachance, KL Trotta, E Smith, C Brion, ...
bioRxiv, 2021.08. 15.456358, 2021
12021
Biosensors for measuring cell signaling in stressed and healthy cells
T Hughes, K Harlen
US Patent App. 16/629,485, 2020
2020
Live-cell biosensors reveal novel insight into neurotoxic and cardiotoxic compound mediated cellular stress response
K Harlen, T Hughes, C Fleming, G Luerman
Journal of Pharmacological and Toxicological Methods 99, 106595, 2019
2019
Thapsigargin-induced cellular stress response and inhibition of Gq-dependent calcium signaling.
JE Clayton, KM Harlen, T Hughes
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
Cell Stress Biosensors for Rapid, Live-Cell Detection of Neurotoxic and Cardiotoxic Compounds in iPSC-Derived Neurons and Cardiomyocytes.
KM Harlen, T Hughes, AM Quinn
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
Watching Biased Agonism at GPCRs in real time.
PH Tewson, AM Quinn, SA Martinka, KM Harlen, TE Hughes
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
A Genetically‐Encoded Fluorescent Assay to Detect Drug Toxicity and Genetic Stress in Living Cells
KM Harlen, T Hughes, AM Quinn
The FASEB Journal 32, lb639-lb639, 2018
2018
GENIe: A bright new genetically‐encoded fluorescent biosensor for monitoring cGMP
KM Harlen, P Tewson, S Martinka, T Hughes, AM Quinn
The FASEB Journal 32, lb638-lb638, 2018
2018
New Fluorescent Tools to Identify Stressed Cells and Interrogate Second Messenger Signaling in Neurodegeneration
T Hughes, K Harlen
Biophysical Journal 114 (3), 287a, 2018
2018
The Regulation of RNA Polymerase II Transcription and Co-Transcriptional Processes
KM Harlen
2016
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