| Efflux-mediated antifungal drug resistance RD Cannon, E Lamping, AR Holmes, K Niimi, PV Baret, MV Keniya, ... Clinical microbiology reviews 22 (2), 291-321, 2009 | 755 | 2009 |
| Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer BC Monk, TM Tomasiak, MV Keniya, FU Huschmann, JDA Tyndall, ... Proceedings of the National Academy of Sciences 111 (10), 3865-3870, 2014 | 310 | 2014 |
| Structural insights into binding of the antifungal drug fluconazole to Saccharomyces cerevisiae lanosterol 14α-demethylase AA Sagatova, MV Keniya, RK Wilson, BC Monk, JDA Tyndall Antimicrobial agents and chemotherapy 59 (8), 4982-4989, 2015 | 209 | 2015 |
| ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates AR Holmes, YH Lin, K Niimi, E Lamping, M Keniya, M Niimi, K Tanabe, ... Antimicrobial agents and chemotherapy 52 (11), 3851-3862, 2008 | 183 | 2008 |
| Targeting efflux pumps to overcome antifungal drug resistance AR Holmes, TS Cardno, JJ Strouse, I Ivnitski-Steele, MV Keniya, ... Future Medicinal Chemistry 8 (12), 1485-1501, 2016 | 141 | 2016 |
| Crystal structures of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provide tools for antifungal discovery MV Keniya, M Sabherwal, RK Wilson, MA Woods, AA Sagatova, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01134-18, 2018 | 136 | 2018 |
| Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design BC Monk, AA Sagatova, P Hosseini, YN Ruma, RK Wilson, MV Keniya Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1868 (3), 140206, 2020 | 126 | 2020 |
| The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of … AR Holmes, MV Keniya, I Ivnitski-Steele, BC Monk, E Lamping, LA Sklar, ... Antimicrobial agents and chemotherapy 56 (3), 1508-1515, 2012 | 115 | 2012 |
| Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase AA Sagatova, MV Keniya, RK Wilson, M Sabherwal, JDA Tyndall, ... Scientific reports 6 (1), 26213, 2016 | 112 | 2016 |
| Structural and functional elucidation of yeast lanosterol 14α-demethylase in complex with agrochemical antifungals JDA Tyndall, M Sabherwal, AA Sagatova, MV Keniya, J Negroni, ... PloS one 11 (12), e0167485, 2016 | 65 | 2016 |
| Inhibitors of the Candida albicans major facilitator superfamily transporter Mdr1p responsible for fluconazole resistance MV Keniya, E Fleischer, A Klinger, RD Cannon, BC Monk PLoS One 10 (5), e0126350, 2015 | 63 | 2015 |
| Role of low-molecular antioxidants in oxidative stress MV Keniya, AI Lukash, EP Gus’kov Usp. Sovrem. Biol 113 (4), 456-470, 1993 | 60 | 1993 |
| Azole resistance reduces susceptibility to the tetrazole antifungal VT-1161 BC Monk, MV Keniya, M Sabherwal, RK Wilson, DO Graham, HF Hassan, ... Antimicrobial Agents and Chemotherapy 63 (1), 10.1128/aac. 02114-18, 2019 | 42 | 2019 |
| Impact of homologous resistance mutations from pathogenic yeast on Saccharomyces cerevisiae lanosterol 14α-demethylase AA Sagatova, MV Keniya, JDA Tyndall, BC Monk Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 02242-17, 2018 | 29 | 2018 |
| Drug Resistance Is Conferred on the Model Yeast Saccharomyces cerevisiae by Expression of Full-Length Melanoma-Associated Human ATP-Binding Cassette … MV Keniya, AR Holmes, M Niimi, E Lamping, JP Gillet, MM Gottesman, ... Molecular pharmaceutics 11 (10), 3452-3462, 2014 | 24 | 2014 |
| Roles for structural biology in the discovery of drugs and agrochemicals targeting sterol 14α-demethylases BC Monk, MV Keniya Journal of Fungi 7 (02), 67, 2021 | 21 | 2021 |
| Heterologous expression of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provides tools for antifungal discovery MV Keniya, YN Ruma, JDA Tyndall, BC Monk Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01131-18, 2018 | 20 | 2018 |
| Impact of Erg11 amino acid substitutions identified in Candida auris clade III isolates on triazole drug susceptibility B Williamson, A Wilk, KD Guerrero, TD Mikulski, TN Elias, I Sawh, ... Antimicrobial agents and chemotherapy 66 (1), e01624-21, 2022 | 15 | 2022 |
| Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host YN Ruma, MV Keniya, JDA Tyndall, BC Monk Journal of Fungi 8 (1), 69, 2022 | 15 | 2022 |
| 9th trends in medical mycology held on 11–14 October 2019, Nice, France, organized under the auspices of EORTC-IDG and ECMM JP Gangneux, O Lortholary, OA Cornely, L Pagano Journal of Fungi 5 (4), 95, 2019 | 12 | 2019 |
Brian C. MonkAssociate Professor, University of OtagoVerified email at otago.ac.nz
