| Axonal transport defects in neurodegenerative diseases GA Morfini, M Burns, LI Binder, NM Kanaan, N LaPointe, DA Bosco, ... Journal of Neuroscience 29 (41), 12776-12786, 2009 | 529 | 2009 |
| Altered metabolism of the amyloid β precursor protein is associated with mitochondrial dysfunction in Down's syndrome J Busciglio, A Pelsman, C Wong, G Pigino, M Yuan, H Mori, BA Yankner Neuron 33 (5), 677-688, 2002 | 459 | 2002 |
| Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport G Pigino, G Morfini, A Pelsman, MP Mattson, ST Brady, J Busciglio Journal of Neuroscience 23 (11), 4499-4508, 2003 | 352 | 2003 |
| A novel CDK5‐dependent pathway for regulating GSK3 activity and kinesin‐driven motility in neurons G Morfini, G Szebenyi, H Brown, HC Pant, G Pigino, S DeBoer, U Beffert, ... The EMBO journal 23 (11), 2235-2245, 2004 | 317 | 2004 |
| Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases NM Kanaan, GA Morfini, NE LaPointe, GF Pigino, KR Patterson, Y Song, ... Journal of Neuroscience 31 (27), 9858-9868, 2011 | 315 | 2011 |
| Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin GA Morfini, YM You, SL Pollema, A Kaminska, K Liu, K Yoshioka, ... Nature neuroscience 12 (7), 864, 2009 | 289 | 2009 |
| The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity NE LaPointe, G Morfini, G Pigino, IN Gaisina, AP Kozikowski, LI Binder, ... Journal of neuroscience research 87 (2), 440-451, 2009 | 283 | 2009 |
| Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta G Pigino, G Morfini, Y Atagi, A Deshpande, C Yu, L Jungbauer, M LaDu, ... Proceedings of the National Academy of Sciences 106 (14), 5907-5912, 2009 | 270 | 2009 |
| Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth G Paglini, G Pigino, P Kunda, G Morfini, R Maccioni, S Quiroga, A Ferreira, ... Journal of Neuroscience 18 (23), 9858-9869, 1998 | 241 | 1998 |
| JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport G Morfini, G Pigino, G Szebenyi, Y You, S Pollema, ST Brady Nature neuroscience 9 (7), 907, 2006 | 222 | 2006 |
| Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system NM Kanaan, GF Pigino, ST Brady, O Lazarov, LI Binder, GA Morfini Experimental neurology 246, 44-53, 2013 | 215 | 2013 |
| Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice YS Hu, P Xu, G Pigino, ST Brady, J Larson, O Lazarov The FASEB Journal 24 (6), 1667-1681, 2010 | 212 | 2010 |
| Analysis of the expression, distribution and function of cyclin dependent kinase 5 (cdk5) in developing cerebellar macroneurons G Pigino, G Paglini, L Ulloa, J Avila, A Cáceres Journal of Cell Science 110 (2), 257-270, 1997 | 185 | 1997 |
| Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling YS Hu, N Long, G Pigino, ST Brady, O Lazarov PLoS One 8 (5), e64460, 2013 | 158 | 2013 |
| Impairments in fast axonal transport and motor neuron deficits in transgenic mice expressing familial Alzheimer's disease-linked mutant presenilin 1 O Lazarov, GA Morfini, G Pigino, A Gadadhar, X Chen, J Robinson, H Ho, ... Journal of Neuroscience 27 (26), 7011-7020, 2007 | 156 | 2007 |
| 1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C G Morfini, G Pigino, K Opalach, Y Serulle, JE Moreira, M Sugimori, ... Proceedings of the National Academy of Sciences 104 (7), 2442-2447, 2007 | 152 | 2007 |
| Presenilin-1 mutations reduce cytoskeletal association, deregulate neurite growth, and potentiate neuronal dystrophy and tau phosphorylation G Pigino, A Pelsman, H Mori, J Busciglio Journal of Neuroscience 21 (3), 834-842, 2001 | 129 | 2001 |
| Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase GA Morfini, DA Bosco, H Brown, R Gatto, A Kaminska, Y Song, L Molla, ... PLoS One 8 (6), e65235, 2013 | 125 | 2013 |
| Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport NM Kanaan, G Morfini, G Pigino, NE LaPointe, A Andreadis, Y Song, ... Neurobiology of aging 33 (4), 826. e15-826. e30, 2012 | 121 | 2012 |
| Fast axonal transport misregulation and Alzheimer’s disease G Morfini, G Pigino, U Beffert, J Busciglio, ST Brady Neuromolecular medicine 2 (2), 89-99, 2002 | 119 | 2002 |
