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Owen S. Fenton
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Advances in biomaterials for drug delivery
OS Fenton, KN Olafson, PS Pillai, MJ Mitchell, R Langer
Advanced Materials 30 (29), 1705328, 2018
7152018
Lipid nanoparticle assisted mRNA delivery for potent cancer immunotherapy
MA Oberli, AM Reichmuth, JR Dorkin, MJ Mitchell, OS Fenton, A Jaklenec, ...
Nano letters 17 (3), 1326-1335, 2017
5952017
Optimization of lipid nanoparticle formulations for mRNA delivery in vivo with fractional factorial and definitive screening designs
KJ Kauffman, JR Dorkin, JH Yang, MW Heartlein, F DeRosa, FF Mir, ...
Nano letters 15 (11), 7300-7306, 2015
5892015
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
KA Whitehead, JR Dorkin, AJ Vegas, PH Chang, O Veiseh, J Matthews, ...
Nature communications 5 (1), 4277, 2014
4992014
Polymer–lipid nanoparticles for systemic delivery of mRNA to the lungs
JC Kaczmarek, AK Patel, KJ Kauffman, OS Fenton, MJ Webber, ...
Angewandte Chemie 128 (44), 14012-14016, 2016
2872016
Bioinspired alkenyl amino alcohol ionizable lipid materials for highly potent in vivo mRNA delivery
OS Fenton, KJ Kauffman, RL McClellan, EA Appel, JR Dorkin, MW Tibbitt, ...
Advanced materials (Deerfield Beach, Fla.) 28 (15), 2939, 2016
2092016
Synthesis and biological evaluation of ionizable lipid materials for the in vivo delivery of messenger RNA to B lymphocytes
OS Fenton, KJ Kauffman, JC Kaczmarek, RL McClellan, S Jhunjhunwala, ...
Advanced Materials 29 (33), 1606944, 2017
1922017
Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells
JC Kaczmarek, KJ Kauffman, OS Fenton, K Sadtler, AK Patel, ...
Nano letters 18 (10), 6449-6454, 2018
1672018
Biomanufacturing for clinically advanced cell therapies
A Aijaz, M Li, D Smith, D Khong, C LeBlon, OS Fenton, RM Olabisi, ...
Nature biomedical engineering 2 (6), 362-376, 2018
1622018
C7-derivatization of C3-alkylindoles including tryptophans and tryptamines
RP Loach, OS Fenton, K Amaike, DS Siegel, E Ozkal, M Movassaghi
The Journal of organic chemistry 79 (22), 11254-11263, 2014
1142014
Exploiting electrostatic interactions in polymer–nanoparticle hydrogels
EA Appel, MW Tibbitt, JM Greer, OS Fenton, K Kreuels, DG Anderson, ...
ACS Macro Letters 4 (8), 848-852, 2015
1012015
Engineering a 3D-bioprinted model of human heart valve disease using nanoindentation-based biomechanics
DC Van der Valk, CFT Van der Ven, MC Blaser, JM Grolman, PJ Wu, ...
Nanomaterials 8 (5), 296, 2018
912018
Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs
OS Fenton, KJ Kauffman, RL McClellan, JC Kaczmarek, MD Zeng, ...
Angewandte Chemie International Edition 57 (41), 13582-13586, 2018
722018
Poly(β‐amino ester)‐co‐poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo
U Capasso Palmiero, JC Kaczmarek, OS Fenton, DG Anderson
Advanced Healthcare Materials 7 (14), 1800249, 2018
672018
Injectable polymer–nanoparticle hydrogels for local immune cell recruitment
OS Fenton, MW Tibbitt, EA Appel, S Jhunjhunwala, MJ Webber, R Langer
Biomacromolecules 20 (12), 4430-4436, 2019
642019
Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A
RP Loach, OS Fenton, M Movassaghi
Journal of the American Chemical Society 138 (3), 1057-1064, 2016
612016
A nanoprimer to improve the systemic delivery of siRNA and mRNA
NRM Saunders, MS Paolini, OS Fenton, L Poul, J Devalliere, F Mpambani, ...
Nano Letters 20 (6), 4264-4269, 2020
552020
Rapid classification of simulated street drug mixtures using Raman spectroscopy and principal component analysis
KY Noonan, LA Tonge, OS Fenton, DB Damiano, KA Frederick
Applied Spectroscopy 63 (7), 742-747, 2009
442009
β‐Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks
OS Fenton, JL Andresen, M Paolini, R Langer
Angewandte Chemie 130 (49), 16258-16261, 2018
412018
Polymers for extended-release administration
MS Paolini, OS Fenton, C Bhattacharya, JL Andresen, R Langer
Biomedical Microdevices 21, 1-24, 2019
332019
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