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Lee L. Rubin
Lee L. Rubin
Professor of Stem Cell and Regenerative Biology, Harvard University
Verified email at harvard.edu
Title
Cited by
Cited by
Year
The cell biology of the blood-brain barrier
LL Rubin, JM Staddon
Annual review of neuroscience 22 (1), 11-28, 1999
13221999
A paracrine requirement for hedgehog signalling in cancer
RL Yauch, SE Gould, SJ Scales, T Tang, H Tian, CP Ahn, D Marshall, ...
Nature 455 (7211), 406-410, 2008
11952008
Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors
L Katsimpardi, NK Litterman, PA Schein, CM Miller, FS Loffredo, ...
Science 344 (6184), 630-634, 2014
10962014
Targeting the Hedgehog pathway in cancer
LL Rubin, FJ de Sauvage
Nature reviews Drug discovery 5 (12), 1026-1033, 2006
10242006
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
J Ham, C Babij, J Whitfield, CM Pfarr, D Lallemand, M Yaniv, LL Rubin
Neuron 14 (5), 927-939, 1995
10171995
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
9652009
A cell culture model of the blood-brain barrier.
LL Rubin, DE Hall, S Porter, K Barbu, C Cannon, HC Horner, M Janatpour, ...
The Journal of cell biology 115 (6), 1725-1735, 1991
9161991
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
R Machold, S Hayashi, M Rutlin, MD Muzumdar, S Nery, JG Corbin, ...
Neuron 39 (6), 937-950, 2003
8702003
Occludin as a possible determinant of tight junction permeability in endothelial cells
T Hirase, JM Staddon, M Saitou, Y Ando-Akatsuka, M Itoh, M Furuse, ...
Journal of cell science 110 (14), 1603-1613, 1997
8161997
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
J Rihel, DA Prober, A Arvanites, K Lam, S Zimmerman, S Jang, ...
Science 327 (5963), 348-351, 2010
7872010
A TALEN genome-editing system for generating human stem cell-based disease models
Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ...
Cell stem cell 12 (2), 238-251, 2013
7062013
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/− p53−/− mice
JT Romer, H Kimura, S Magdaleno, K Sasai, C Fuller, H Baines, ...
Cancer cell 6 (3), 229-240, 2004
6342004
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
S Chen, M Borowiak, JL Fox, R Maehr, K Osafune, L Davidow, K Lam, ...
Nature chemical biology 5 (4), 258-265, 2009
6152009
In silico labeling: predicting fluorescent labels in unlabeled images
EM Christiansen, SJ Yang, DM Ando, A Javaherian, G Skibinski, S Lipnick, ...
Cell 173 (3), 792-803. e19, 2018
6032018
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
M Frank-Kamenetsky, XM Zhang, S Bottega, O Guicherit, H Wichterle, ...
Journal of biology 1, 1-19, 2002
5982002
A comparison of non-integrating reprogramming methods
TM Schlaeger, L Daheron, TR Brickler, S Entwisle, K Chan, A Cianci, ...
Nature biotechnology 33 (1), 58-63, 2015
5702015
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
NA Naryshkin, M Weetall, A Dakka, J Narasimhan, X Zhao, Z Feng, ...
science 345 (6197), 688-693, 2014
5662014
Single-cell transcriptomic profiling of the aging mouse brain
M Ximerakis, SL Lipnick, BT Innes, SK Simmons, X Adiconis, D Dionne, ...
Nature neuroscience 22 (10), 1696-1708, 2019
5232019
GDC-0449—A potent inhibitor of the hedgehog pathway
KD Robarge, SA Brunton, GM Castanedo, Y Cui, MS Dina, R Goldsmith, ...
Bioorganic & medicinal chemistry letters 19 (19), 5576-5581, 2009
4612009
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
A Watson, A Eilers, D Lallemand, J Kyriakis, LL Rubin, J Ham
Journal of Neuroscience 18 (2), 751-762, 1998
4521998
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