Lee L. Rubin
Lee L. Rubin
Professor of Stem Cell and Regenerative Biology, Harvard University
Verified email at
Cited by
Cited by
The cell biology of the blood-brain barrier
LL Rubin, JM Staddon
Annual review of neuroscience 22 (1), 11-28, 1999
A paracrine requirement for hedgehog signalling in cancer
RL Yauch, SE Gould, SJ Scales, T Tang, H Tian, CP Ahn, D Marshall, ...
Nature 455 (7211), 406-410, 2008
Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors
L Katsimpardi, NK Litterman, PA Schein, CM Miller, FS Loffredo, ...
Science 344 (6184), 630-634, 2014
Targeting the Hedgehog pathway in cancer
LL Rubin, FJ de Sauvage
Nature reviews Drug discovery 5 (12), 1026-1033, 2006
A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death
J Ham, C Babij, J Whitfield, CM Pfarr, D Lallemand, M Yaniv, LL Rubin
Neuron 14 (5), 927-939, 1995
A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...
Cell stem cell 5 (5), 491-503, 2009
A cell culture model of the blood-brain barrier.
LL Rubin, DE Hall, S Porter, K Barbu, C Cannon, HC Horner, M Janatpour, ...
The Journal of cell biology 115 (6), 1725-1735, 1991
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
R Machold, S Hayashi, M Rutlin, MD Muzumdar, S Nery, JG Corbin, ...
Neuron 39 (6), 937-950, 2003
Occludin as a possible determinant of tight junction permeability in endothelial cells
T Hirase, JM Staddon, M Saitou, Y Ando-Akatsuka, M Itoh, M Furuse, ...
Journal of cell science 110 (14), 1603-1613, 1997
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
J Rihel, DA Prober, A Arvanites, K Lam, S Zimmerman, S Jang, ...
Science 327 (5963), 348-351, 2010
A TALEN genome-editing system for generating human stem cell-based disease models
Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ...
Cell stem cell 12 (2), 238-251, 2013
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/− p53−/− mice
JT Romer, H Kimura, S Magdaleno, K Sasai, C Fuller, H Baines, ...
Cancer cell 6 (3), 229-240, 2004
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
S Chen, M Borowiak, JL Fox, R Maehr, K Osafune, L Davidow, K Lam, ...
Nature chemical biology 5 (4), 258-265, 2009
In silico labeling: predicting fluorescent labels in unlabeled images
EM Christiansen, SJ Yang, DM Ando, A Javaherian, G Skibinski, S Lipnick, ...
Cell 173 (3), 792-803. e19, 2018
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
M Frank-Kamenetsky, XM Zhang, S Bottega, O Guicherit, H Wichterle, ...
Journal of biology 1, 1-19, 2002
A comparison of non-integrating reprogramming methods
TM Schlaeger, L Daheron, TR Brickler, S Entwisle, K Chan, A Cianci, ...
Nature biotechnology 33 (1), 58-63, 2015
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
NA Naryshkin, M Weetall, A Dakka, J Narasimhan, X Zhao, Z Feng, ...
science 345 (6197), 688-693, 2014
Single-cell transcriptomic profiling of the aging mouse brain
M Ximerakis, SL Lipnick, BT Innes, SK Simmons, X Adiconis, D Dionne, ...
Nature neuroscience 22 (10), 1696-1708, 2019
GDC-0449—A potent inhibitor of the hedgehog pathway
KD Robarge, SA Brunton, GM Castanedo, Y Cui, MS Dina, R Goldsmith, ...
Bioorganic & medicinal chemistry letters 19 (19), 5576-5581, 2009
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
A Watson, A Eilers, D Lallemand, J Kyriakis, LL Rubin, J Ham
Journal of Neuroscience 18 (2), 751-762, 1998
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