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Graham M Hughes
Graham M Hughes
Verified email at ucd.ie
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Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates
J Damas, GM Hughes, KC Keough, CA Painter, NS Persky, M Corbo, ...
Proceedings of the National Academy of Sciences 117 (36), 22311-22322, 2020
6252020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6132020
Six reference-quality genomes reveal evolution of bat adaptations
D Jebb, Z Huang, M Pippel, GM Hughes, K Lavrichenko, P Devanna, ...
Nature 583 (7817), 578-584, 2020
2402020
Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species
EC Teeling, SC Vernes, LM Dávalos, DA Ray, MTP Gilbert, E Myers, ...
Annual review of animal biosciences 6, 23-46, 2018
2052018
Genome-wide signatures of complex introgression and adaptive evolution in the big cats
HV Figueiró, G Li, FJ Trindade, J Assis, F Pais, G Fernandes, SHD Santos, ...
Science Advances 3 (7), e1700299, 2017
1582017
Growing old, yet staying young: the role of telomeres in bats’ exceptional longevity
NM Foley, GM Hughes, Z Huang, M Clarke, D Jebb, CV Whelan, EJ Petit, ...
Science Advances 4 (2), eaao0926, 2018
1522018
The birth and death of olfactory receptor gene families in mammalian niche adaptation
GM Hughes, ESM Boston, JA Finarelli, WJ Murphy, DG Higgins, ...
Molecular biology and evolution 35 (6), 1390-1406, 2018
1052018
A novel method of microsatellite genotyping-by-sequencing using individual combinatorial barcoding
S Vartia, JL Villanueva-Cañas, J Finarelli, ED Farrell, PC Collins, ...
Royal Society Open Science 3 (1), 150565, 2016
752016
Evolutionary constraint and innovation across hundreds of placental mammals
MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ...
Science 380 (6643), eabn3943, 2023
702023
A potent anti-inflammatory response in bat macrophages may be linked to extended longevity and viral tolerance
J Kacprzyk, GM Hughes, EM Palsson-McDermott, SR Quinn, ...
Acta chiropterologica 19 (2), 219-228, 2017
582017
Drivers of longitudinal telomere dynamics in a long‐lived bat species, Myotis myotis
NM Foley, EJ Petit, T Brazier, JA Finarelli, GM Hughes, F Touzalin, ...
Molecular Ecology 29 (16), 2963-2977, 2020
522020
Large‐scale genome sampling reveals unique immunity and metabolic adaptations in bats
DD Moreno Santillan, TM Lama, YT Gutierrez Guerrero, AM Brown, ...
Molecular ecology 30 (23), 6449-6467, 2021
502021
Genome analysis of the metabolically versatile Pseudomonas umsongensis GO16: the genetic basis for PET monomer upcycling into polyhydroxyalkanoates
T Narancic, M Salvador, GM Hughes, N Beagan, U Abdulmutalib, ...
Microbial biotechnology 14 (6), 2463-2480, 2021
502021
A genomic timescale for placental mammal evolution
NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ...
Science 380 (6643), eabl8189, 2023
432023
Loss of olfactory receptor function in hominin evolution
GM Hughes, EC Teeling, DG Higgins
PLoS One 9 (1), e84714, 2014
382014
Integrating gene annotation with orthology inference at scale
BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ...
Science 380 (6643), eabn3107, 2023
372023
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ...
Science 380 (6643), eabn2937, 2023
372023
As blind as a bat? Opsin phylogenetics illuminates the evolution of color vision in bats
BF Simoes, NM Foley, GM Hughes, H Zhao, S Zhang, SJ Rossiter, ...
Molecular biology and evolution 36 (1), 54-68, 2019
352019
Is there a link between aging and microbiome diversity in exceptional mammalian longevity?
GM Hughes, J Leech, SJ Puechmaille, JV Lopez, EC Teeling
PeerJ 6, e4174, 2018
332018
Three-dimensional genome rewiring in loci with human accelerated regions
KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ...
Science 380 (6643), eabm1696, 2023
282023
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