Michele Mishto
Michele Mishto
King's College London | School of Immunology & Microbial Sciences| Peter Gorer Department of
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A large fraction of HLA class I ligands are proteasome-generated spliced peptides
J Liepe, F Marino, J Sidney, A Jeko, DE Bunting, A Sette, PM Kloetzel, ...
Science 354 (6310), 354-358, 2016
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains
M Mishto, E Bellavista, A Santoro, A Stolzing, C Ligorio, B Nacmias, ...
Neurobiology of aging 27 (1), 54-66, 2006
Neuroinflammatory targets and treatments for epilepsy validated in experimental models
E Aronica, S Bauer, Y Bozzi, M Caleo, R Dingledine, JA Gorter, ...
Epilepsia 58, 27-38, 2017
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease
A Santoro, V Balbi, E Balducci, C Pirazzini, F Rosini, F Tavano, A Achilli, ...
PloS one 5 (8), e12037, 2010
The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death
M Bonafé, S Salvioli, C Barbi, C Trapassi, F Tocco, G Storci, L Invidia, ...
Cell Death & Differentiation 11 (9), 962-973, 2004
Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
M Mishto, J Liepe, K Textoris‐Taube, C Keller, P Henklein, M Weberruß, ...
European Journal of Immunology 44 (12), 3508-3521, 2014
Immunoproteasomes and immunosenescence
M Mishto, A Santoro, E Bellavista, M Bonafé, D Monti, C Franceschi
Ageing Research Reviews 2 (4), 419-432, 2003
Proteasomes generate spliced epitopes by two different mechanisms and as efficiently as non-spliced epitopes
F Ebstein, K Textoris-Taube, C Keller, R Golnik, N Vigneron, ...
Scientific reports 6 (1), 24032, 2016
Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system
P Tieri, A Grignolio, A Zaikin, M Mishto, D Remondini, GC Castellani, ...
Theoretical Biology and Medical Modelling 7, 1-16, 2010
Genes, ageing and longevity in humans: problems, advantages and perspectives
S Salvioli, F Olivieri, F Marchegiani, M Cardelli, A Santoro, E Bellavista, ...
Free Radical Research 40 (12), 1303-1323, 2006
Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies
E Cevenini, E Bellavista, P Tieri, G Castellani, F Lescai, M Francesconi, ...
Current pharmaceutical design 16 (7), 802-813, 2010
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population
M Mishto, E Bellavista, C Ligorio, K Textoris-Taube, A Santoro, ...
PloS one 5 (2), e9287, 2010
Driving forces of proteasome-catalyzed peptide splicing in yeast and humans
M Mishto, A Goede, KT Taube, C Keller, K Janek, P Henklein, ...
Molecular & Cellular Proteomics 11 (10), 1008-1023, 2012
The 20S proteasome splicing activity discovered by SpliceMet
J Liepe, M Mishto, K Textoris-Taube, K Janek, C Keller, P Henklein, ...
PLOS Computational Biology 6 (6), e1000830, 2010
Effects of donepezil, galantamine and rivastigmine in 938 Italian patients with Alzheimer’s disease: a prospective, observational study
A Santoro, P Siviero, N Minicuci, E Bellavista, M Mishto, F Olivieri, ...
CNS drugs 24, 163-176, 2010
Towards a liquid self: how time, geography, and life experiences reshape the biological identity
A Grignolio, M Mishto, AMC Faria, P Garagnani, C Franceschi, P Tieri
Frontiers in Immunology 5, 153, 2014
Post-translational peptide splicing and T cell responses
M Mishto, J Liepe
Trends in Immunology 38 (12), 904-915, 2017
Mapping the MHC class I–spliced immunopeptidome of cancer cells
J Liepe, J Sidney, FKM Lorenz, A Sette, M Mishto
Cancer immunology research 7 (1), 62-76, 2019
A mathematical model of protein degradation by the proteasome
F Luciani, C Keşmir, M Mishto, M Or-Guil, RJ De Boer
Biophysical journal 88 (4), 2422-2432, 2005
Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection
ACM Platteel, J Liepe, K Textoris-Taube, C Keller, P Henklein, ...
Cell reports 20 (5), 1242-1253, 2017
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