The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 459 | 2015 |
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ... Nature genetics 50 (1), 83-95, 2018 | 195 | 2018 |
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer L Puca, K Gavyert, V Sailer, V Conteduca, E Dardenne, M Sigouros, ... Science translational medicine 11 (484), eaav0891, 2019 | 170 | 2019 |
Epigenomic evolution in diffuse large B-cell lymphomas H Pan, Y Jiang, M Boi, F Tabbň, D Redmond, K Nie, M Ladetto, ... Nature communications 6 (1), 1-12, 2015 | 132 | 2015 |
QSER1 protects DNA methylation valleys from de novo methylation G Dixon, H Pan, D Yang, BP Rosen, T Jashari, N Verma, J Pulecio, ... Science 372 (6538), eabd0875, 2021 | 88 | 2021 |
Discovery of candidate DNA methylation cancer driver genes H Pan, L Renaud, R Chaligne, J Bloehdorn, E Tausch, D Mertens, ... Cancer discovery 11 (9), 2266-2281, 2021 | 60 | 2021 |
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes D Liu, JE Shoag, D Poliak, RS Goueli, V Ravikumar, D Redmond, ... Nature communications 11 (1), 1987, 2020 | 54 | 2020 |
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy T Dalton, E Doubrovina, D Pankov, R Reynolds, H Scholze, A Selvakumar, ... Blood, The Journal of the American Society of Hematology 135 (21), 1870-1881, 2020 | 46 | 2020 |
Extracellular matrix in synthetic hydrogel‐based prostate cancer organoids regulate therapeutic response to EZH2 and DRD2 inhibitors MJ Mosquera, S Kim, R Bareja, Z Fang, S Cai, H Pan, M Asad, ML Martin, ... Advanced Materials 34 (2), 2100096, 2022 | 43 | 2022 |
CIC is a critical regulator of neuronal differentiation I Hwang, H Pan, J Yao, O Elemento, H Zheng, J Paik JCI insight 5 (9), 2020 | 34 | 2020 |
TETs regulate proepicardial cell migration through extracellular matrix organization during zebrafish cardiogenesis Y Lan, H Pan, C Li, KM Banks, J Sam, B Ding, O Elemento, MG Goll, ... Cell reports 26 (3), 720-732. e4, 2019 | 31 | 2019 |
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions SE Schad, A Chow, L Mangarin, H Pan, J Zhang, N Ceglia, JX Caushi, ... Journal of Experimental Medicine 219 (6), e20212169, 2022 | 28 | 2022 |
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes M Boi, M Todaro, V Vurchio, SN Yang, J Moon, I Kwee, A Rinaldi, H Pan, ... Oncotarget 7 (48), 79637, 2016 | 25 | 2016 |
Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, ... Cell Reports 37 (10), 2021 | 22 | 2021 |
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia J Bloehdorn, A Braun, A Taylor-Weiner, BMC Jebaraj, S Robrecht, ... Nature Communications 12 (1), 5395, 2021 | 22 | 2021 |
A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas JY Jang, I Hwang, H Pan, J Yao, L Alinari, E Imada, C Zanettini, MJ Kluk, ... The Journal of Clinical Investigation 132 (24), 2022 | 18 | 2022 |
Epigenetic analysis identifies factors driving racial disparity in prostate cancer R Rai, SS Yadav, H Pan, I Khan, J O'Connor, M Alshalalfa, E Davicioni, ... Cancer Reports 2 (2), e1153, 2019 | 17 | 2019 |
Analyzing DNA methylation patterns during tumor evolution H Pan, O Elemento Cancer Systems Biology: Methods and Protocols, 27-53, 2018 | 9 | 2018 |
Utility of multimodality molecular profiling for pediatric patients with central nervous system tumors P Rajappa, KW Eng, R Bareja, ED Bander, M Yuan, A Dua, ... Neuro-Oncology Advances 4 (1), vdac031, 2022 | 6 | 2022 |
Abstract LB-064: characterization of the tumor suppressor function of the lysine-specific methyltransferase KMT2D in follicular lymphoma A Ortega-Molina, I Boss, H Pan, Y Jiang, D Hu, X Gao, R Shaknovich, ... Cancer Research 75 (15_Supplement), LB-064-LB-064, 2015 | 2 | 2015 |