Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies KH Strang, CL Croft, ZA Sorrentino, P Chakrabarty, TE Golde, BI Giasson Journal of Biological Chemistry 293 (7), 2408-2421, 2018 | 135 | 2018 |
Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain K Kurbatskaya, EC Phillips, CL Croft, G Dentoni, MM Hughes, MA Wade, ... Acta neuropathologica communications 4 (1), 34, 2016 | 135 | 2016 |
Organotypic brain slice cultures to model neurodegenerative proteinopathies CL Croft, HS Futch, BD Moore, TE Golde Molecular Neurodegeneration 14 (1), 45, 2019 | 120 | 2019 |
Astrocytes and neuroinflammation in Alzheimer's disease. EC Phillips, CL Croft, K Kurbatskaya, MJ O'Neill, ML Hutton, DP Hanger, ... Biochemical Society transactions 42 (5), 1321-1325, 2014 | 120 | 2014 |
Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. CL Croft, MA Wade, K Kurbatskaya, P Mastrandreas, MM Hughes, ... Cell Death Disease 8 (3), e2671, 2017 | 68 | 2017 |
Targeting psychologic stress signaling pathways in Alzheimer’s disease HS Futch, CL Croft, VQ Truong, EG Krause, TE Golde Molecular Neurodegeneration 12 (1), 49, 2017 | 63 | 2017 |
rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies CL Croft, PE Cruz, DH Ryu, C Ceballos-Diaz, KH Strang, BM Woody, ... Journal of Experimental Medicine 216 (3), 539-555, 2019 | 55 | 2019 |
Preparation of organotypic brain slice cultures for the study of Alzheimer’s disease CL Croft, W Noble F1000Research 7, 2018 | 55 | 2018 |
Calpain cleavage and inactivation of the sodium calcium exchanger‐3 occur downstream of Aβ in Alzheimer's disease J Atherton, K Kurbatskaya, M Bondulich, CL Croft, CJ Garwood, ... Aging cell 13 (1), 49-59, 2014 | 55 | 2014 |
Constant light enhances synchrony among circadian clock cells and promotes behavioral rhythms in VPAC2-signaling deficient mice ATL Hughes, CL Croft, RE Samuels, J Myung, T Takumi, HD Piggins Scientific reports 5, 14044, 2015 | 37 | 2015 |
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy B Khalil, D Chhangani, MC Wren, CL Smith, JH Lee, X Li, C Puttinger, ... Molecular Neurodegeneration 17 (1), 1-27, 2022 | 24 | 2022 |
Inhibition of glycogen synthase kinase-3 by BTA-EG 4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease CL Croft, K Kurbatskaya, DP Hanger, W Noble Scientific Reports 7 (1), 7434, 2017 | 24 | 2017 |
Novel monoclonal antibodies targeting the microtubule-binding domain of human tau CL Croft, BD Moore, Y Ran, P Chakrabarty, Y Levites, TE Golde, ... PloS one 13 (4), e0195211, 2018 | 21 | 2018 |
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions CL Croft, MS Goodwin, DH Ryu, CB Lessard, G Tejeda, M Marrero, ... Acta Neuropathologica, 1-23, 2021 | 18 | 2021 |
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS MS Goodwin, CL Croft, HS Futch, D Ryu, C Ceballos-Diaz, X Liu, ... Molecular Neurodegeneration 15 (1), 1-16, 2020 | 16 | 2020 |
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes HS Futch, KN McFarland, BD Moore, MZ Kuhn, BI Giasson, TB Ladd, ... Journal of Experimental Medicine 216 (11), 2479-2491, 2019 | 16 | 2019 |
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice Y Xia, S Prokop, BM Bell, KMM Gorion, CL Croft, L Nasif, G Xu, CJ Riffe, ... Communications biology 5 (1), 1-18, 2022 | 12 | 2022 |
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes P Beltran-Lobo, MM Hughes, C Troakes, CL Croft, H Rupawala, D Jutzi, ... Brain, Behavior, and Immunity, 2023 | 10 | 2023 |
SIRT1: A Novel Way to Target Tau? HS Futch, CL Croft The Journal of Neuroscience 38 (36), 7755, 2018 | 8 | 2018 |
Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection F Yang, P Beltran-Lobo, K Sung, C Goldrick, CL Croft, A Nishimura, ... Science Advances 10 (12), eadk9884, 2024 | 7 | 2024 |