The good and the bad collagens of fibrosis–their role in signaling and organ function MA Karsdal, SH Nielsen, DJ Leeming, LL Langholm, MJ Nielsen, ... Advanced drug delivery reviews 121, 43-56, 2017 | 405 | 2017 |
Extracellular matrix remodeling: the common denominator in connective tissue diseases possibilities for evaluation and current understanding of the matrix as more than a … MA Karsdal, MJ Nielsen, JM Sand, K Henriksen, F Genovese, ... Assay and drug development technologies 11 (2), 70-92, 2013 | 285 | 2013 |
Novel insights into the function and dynamics of extracellular matrix in liver fibrosis MA Karsdal, T Manon-Jensen, F Genovese, JH Kristensen, MJ Nielsen, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (10 …, 2015 | 245 | 2015 |
MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis–validation of two novel … JM Sand, L Larsen, C Hogaboam, F Martinez, ML Han, M Røssel Larsen, ... PloS one 8 (12), e84934, 2013 | 196 | 2013 |
Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis DJ Leeming, JM Sand, MJ Nielsen, F Genovese, FJ Martinez, ... Biomarker insights 7, BMI. S9415, 2012 | 102 | 2012 |
Accelerated extracellular matrix turnover during exacerbations of COPD JMB Sand, AJ Knox, P Lange, S Sun, JH Kristensen, DJ Leeming, ... Respiratory research 16, 1-8, 2015 | 91 | 2015 |
the efficacy of biomarkers in chronic fibroproliferative diseases–early diagnosis and prognosis, with liver fibrosis as an exemplar MA Karsdal, H Krarup, JMB Sand, PB Christensen, J Gerstoft, DJ Leeming, ... Alimentary pharmacology & therapeutics 40 (3), 233-249, 2014 | 89 | 2014 |
Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD AR Bihlet, MA Karsdal, JMB Sand, DJ Leeming, M Roberts, W White, ... Respiratory Research 18, 1-11, 2017 | 76 | 2017 |
Systemic biomarkers of collagen and elastin turnover are associated with clinically relevant outcomes in COPD D Stolz, DJ Leeming, JHE Kristensen, MA Karsdal, W Boersma, R Louis, ... Chest 151 (1), 47-59, 2017 | 66 | 2017 |
High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD–results from the ECLIPSE study JMB Sand, DJ Leeming, I Byrjalsen, AR Bihlet, P Lange, R Tal-Singer, ... Respiratory research 17, 1-12, 2016 | 66 | 2016 |
Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling JH Kristensen, MA Karsdal, JMB Sand, N Willumsen, C Diefenbach, ... BMC pulmonary medicine 15, 1-7, 2015 | 53 | 2015 |
Type IV collagen JMB Sand, F Genovese, MA Karsdal Biochemistry of collagens, laminins and elastin, 31-41, 2016 | 50 | 2016 |
Type VIII collagen is elevated in diseases associated with angiogenesis and vascular remodeling NUB Hansen, N Willumsen, JMB Sand, L Larsen, MA Karsdal, ... Clinical biochemistry 49 (12), 903-908, 2016 | 49 | 2016 |
Collagen degradation and formation are elevated in exacerbated COPD compared with stable disease DM Schumann, D Leeming, E Papakonstantinou, F Blasi, K Kostikas, ... Chest 154 (4), 798-807, 2018 | 45 | 2018 |
Characterization of serological neo-epitope biomarkers reflecting collagen remodeling in clinically stable chronic obstructive pulmonary disease JMB Sand, G Martinez, AK Midjord, MA Karsdal, DJ Leeming, P Lange Clinical biochemistry 49 (15), 1144-1151, 2016 | 43 | 2016 |
Lung tissue destruction by proteinase 3 and cathepsin G mediated elastin degradation is elevated in chronic obstructive pulmonary disease NS Gudmann, T Manon-Jensen, JMB Sand, C Diefenbach, S Sun, ... Biochemical and biophysical research communications 503 (3), 1284-1290, 2018 | 36 | 2018 |
Levels of circulating MMP-7 degraded elastin are elevated in pulmonary disorders JH Kristensen, L Larsen, B Dasgupta, C Brodmerkel, M Curran, ... Clinical biochemistry 48 (16-17), 1083-1088, 2015 | 35 | 2015 |
Biochemistry of collagens, laminins and elastin JMB Sand, F Genovese, MA Karsdal Academic Press, 2016 | 33 | 2016 |
Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis H Jessen, N Hoyer, TS Prior, P Frederiksen, MA Karsdal, DJ Leeming, ... Respiratory Research 22, 1-8, 2021 | 31 | 2021 |
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis SR Rønnow, RQ Dabbagh, F Genovese, CB Nanthakumar, VJ Barrett, ... Respiratory research 21, 1-14, 2020 | 31 | 2020 |