Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells VM Maher, LM Ouellette, RD Curren, JJ McCormick Nature 261 (5561), 593-595, 1976 | 390 | 1976 |
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity … H Spielmann, S Hoffmann, M Liebsch, P Botham, JH Fentem, C Eskes, ... Alternatives to laboratory animals 35 (6), 559-601, 2007 | 249 | 2007 |
The ECVAM international validation study on in vitro tests for skin corrosivity. 2. Results and evaluation by the Management Team JH Fentem, GEB Archer, M Balls, PA Botham, RD Curren, LK Earl, ... Toxicology in vitro 12 (4), 483-524, 1998 | 212 | 1998 |
The role of prevalidation in the development, validation and acceptance of alternative methods RD Curren, JA Southee, H Spielmann, M Liebsch, JH Fentem, M Balls Alternatives to Laboratory Animals 23 (2), 211-217, 1995 | 194 | 1995 |
An evaluation of food flavoring ingredients in a genetic toxicity screening battery JD Heck, TA Vollmuth, MA Cifone, DR Jagannath, B Myhr, RD Curren Toxicologist 9, 257, 1989 | 192 | 1989 |
MEIC Evaluation of Acute Systemic Toxicity: Part II. In Vitro Results from 68 Toxicity Assays Used to Test the First 30 Reference Chemicals and a Comparative … C Clemedson, E McFarlane-Abdulla, M Andersson, FA Barile, MC Calleja, ... Alternatives to laboratory animals 24 (1_part_1), 273-311, 1996 | 186 | 1996 |
Cell Transformation Assays as Predictors of Human Carcinogenicity: The Report and Recommendations of ECVAM Workshop 39– R Combes, M Balls, R Curren, M Fischbach, N Fusenig, D Kirkland, ... Alternatives to laboratory animals 27 (5), 745-767, 1999 | 139 | 1999 |
Genotoxicity of formaldehyde in cultured human bronchial fibroblasts RC Grafstrom, RD Curren, LL Yang, CC Harris Science 228 (4695), 89-91, 1985 | 132 | 1985 |
Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm™) RD Curren, GC Mun, DP Gibson, MJ Aardema Mutation Research/Genetic Toxicology and Environmental Mutagenesis 607 (2 …, 2006 | 125 | 2006 |
In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop S Pfuhler, M Fellows, J van Benthem, R Corvi, R Curren, K Dearfield, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 723 (2 …, 2011 | 119 | 2011 |
Eye irritation testing: the way forward M Balls, N Berg, LH Bruner, RD Curren, O De Silva, LK Earl, DJ Esdaile, ... ATLA-NOTTINGHAM- 27, 53-78, 1999 | 119 | 1999 |
In Vitro Human Tissue Models in Risk Assessment: Report of a Consensus-Building Workshop JT MacGregor, JM Collins, Y Sugiyama, CA Tyson, J Dean, L Smith, ... Toxicological Sciences 59 (1), 17-36, 2001 | 117 | 2001 |
Mutagenesis of xeroderma pigmentosum fibroblasts by acrolein RD Curren, LL Yang, PM Conklin, RC Grafstrom, CC Harris Mutation Research Letters 209 (1-2), 17-22, 1988 | 109 | 1988 |
The Second ECVAM Workshop on Phototoxicity Testing: The Report and Recommendations of ECVAM Workshop 42, H Spielmann, L Müller, D Averbeck, M Balls, S Brendler-Schwaab, ... Alternatives to Laboratory Animals 28 (6), 777-814, 2000 | 104 | 2000 |
MEIC evaluation of acute systemic toxicity. Part VII. Prediction of human toxicity by results from testing of the first 30 reference chemicals with 27 further in vitro assays C Clemedson, FA Barile, C Chesne, M Cottin, R Curren, B Ekwall, M Ferro, ... ATLA 28 (1), 161-200, 2000 | 95 | 2000 |
The CFTA evaluation of alternatives program: an evaluation of in vitro alternatives to the Draize primary eye irritation test.(Phase III) Surfactant-based formulations SD Gettings, RA Lordo, KL Hintze, DM Bagley, PL Casterton, ... Food and Chemical Toxicology 34 (1), 79-117, 1996 | 94 | 1996 |
Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts RC Grafström, JM Dypbukt, K Sundqvist, L Atzori, I Nielsen, RD Curren, ... Carcinogenesis 15 (5), 985-990, 1994 | 93 | 1994 |
The principles of weight of evidence validation of test methods and testing strategies: The report and recommendations of ECVAM workshop 58 M Balls, P Amcoff, S Bremer, S Casati, S Coecke, R Clothier, R Combes, ... Alternatives to laboratory animals 34 (6), 603-620, 2006 | 85 | 2006 |
Ocular Safety: A Silent (In Vitro) Success Story RD Curren, JW Harbell Alternatives to Laboratory Animals 30 (2_suppl), 69-74, 2002 | 84 | 2002 |
Validation of alternative methods for toxicity testing LH Bruner, GJ Carr, M Chamberlain, RD Curren Toxicology in Vitro 10 (4), 479-501, 1996 | 80 | 1996 |