David M McCandlish
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A novel roll-and-slide mechanism of DNA folding in chromatin: implications for nucleosome positioning
MY Tolstorukov, AV Colasanti, DM McCandlish, WK Olson, VB Zhurkin
Journal of molecular biology 371 (3), 725-738, 2007
Contingency and entrenchment in protein evolution under purifying selection
P Shah, DM McCandlish, JB Plotkin
Proceedings of the National Academy of Sciences 112 (25), E3226-E3235, 2015
Inferring the shape of global epistasis
J Otwinowski, DM McCandlish, JB Plotkin
Proceedings of the National Academy of Sciences 115 (32), E7550-E7558, 2018
Modeling evolution using the probability of fixation: history and implications
DM McCandlish, A Stoltzfus
The Quarterly review of biology 89 (3), 225-252, 2014
Visualizing fitness landscapes
DM McCandlish
Evolution 65 (6), 1544-1558, 2011
Massively parallel assays and quantitative sequence–function relationships
JB Kinney, DM McCandlish
Annual review of genomics and human genetics 20, 99-127, 2019
Mutational biases influence parallel adaptation
A Stoltzfus, DM McCandlish
Molecular biology and evolution 34 (9), 2163-2172, 2017
Epistasis and the dynamics of reversion in molecular evolution
DM McCandlish, P Shah, JB Plotkin
Genetics 203 (3), 1335-1351, 2016
The role of epistasis in protein evolution
DM McCandlish, E Rajon, P Shah, Y Ding, JB Plotkin
Nature 497 (7451), E1-E2, 2013
The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function
JF Storz, C Natarajan, AV Signore, CC Witt, DM McCandlish, A Stoltzfus
Philosophical Transactions of the Royal Society B 374 (1777), 20180238, 2019
MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect
A Tareen, M Kooshkbaghi, A Posfai, WT Ireland, DM McCandlish, ...
Genome biology 23 (1), 98, 2022
Mutation bias shapes the spectrum of adaptive substitutions
AV Cano, H Rozhoňová, A Stoltzfus, DM McCandlish, JL Payne
Proceedings of the National Academy of Sciences 119 (7), e2119720119, 2022
Formal properties of the probability of fixation: identities, inequalities and approximations
DM McCandlish, CL Epstein, JB Plotkin
Theoretical population biology 99, 98-113, 2015
Minimum epistasis interpolation for sequence-function relationships
J Zhou, DM McCandlish
Nature communications 11 (1), 1782, 2020
Detecting epistasis from an ensemble of adapting populations
DM McCandlish, J Otwinowski, JB Plotkin
Evolution 69 (9), 2359-2370, 2015
On the findability of genotypes
DM McCandlish
Evolution 67 (9), 2592-2603, 2013
Assortative mating can impede or facilitate fixation of underdominant alleles
MG Newberry, DM McCandlish, JB Plotkin
Theoretical population biology 112, 14-21, 2016
The inevitability of unconditionally deleterious substitutions during adaptation
DM McCandlish, CL Epstein, JB Plotkin
Evolution 68 (5), 1351-1364, 2014
Higher-order epistasis and phenotypic prediction
J Zhou, MS Wong, WC Chen, AR Krainer, JB Kinney, DM McCandlish
Proceedings of the National Academy of Sciences 119 (39), e2204233119, 2022
Long-term evolution on complex fitness landscapes when mutation is weak
DM McCandlish
Heredity 121 (5), 449-465, 2018
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