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Enric Domingo
Enric Domingo
Department of Oncology, University of Oxford
Verified email at oncology.ox.ac.uk
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Year
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
C Palles, JB Cazier, KM Howarth, E Domingo, AM Jones, P Broderick, ...
Nature genetics 45 (2), 136-144, 2013
10862013
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
9132013
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23. 3
IPM Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, K Howarth, ...
Nature genetics 40 (5), 623-630, 2008
6552008
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ...
Nature genetics 39 (11), 1315-1317, 2007
6112007
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
L Carvajal-Carmona, K Howarth, E Jaeger, SL Spain, A Walther, ...
Nature genetics 40 (12), 1426-1435, 2008
6062008
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
OJ Skrede, S De Raedt, A Kleppe, TS Hveem, K Liestřl, J Maddison, ...
The Lancet 395 (10221), 350-360, 2020
4472020
BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing
E Domingo, P Laiho, M Ollikainen, M Pinto, L Wang, AJ French, J Westra, ...
Journal of medical genetics 41 (9), 664-668, 2004
4302004
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33
RS Houlston, J Cheadle, SE Dobbins, A Tenesa, AM Jones, K Howarth, ...
Nature genetics 42 (11), 973-977, 2010
4252010
DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer
DN Church, SEW Briggs, C Palles, E Domingo, SJ Kearsey, JM Grimes, ...
Human molecular genetics 22 (14), 2820-2828, 2013
3922013
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13. 3 influence colorectal cancer risk
E Jaeger, E Webb, K Howarth, L Carvajal-Carmona, A Rowan, ...
Nature genetics 40 (1), 26-28, 2008
3532008
The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial
A Huijbers, R Tollenaar, GW v Pelt, ECM Zeestraten, S Dutton, ...
Annals of oncology 24 (1), 179-185, 2013
3092013
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study
E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ...
The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016
2862016
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression
C Oliveira, S Velho, C Moutinho, A Ferreira, A Preto, E Domingo, ...
Oncogene 26 (1), 158-163, 2007
2852007
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
MG Dunlop, SE Dobbins, SM Farrington, AM Jones, C Palles, N Whiffin, ...
Nature genetics 44 (7), 770-776, 2012
2812012
Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis
D Rosmarin, C Palles, D Church, E Domingo, A Jones, E Johnstone, ...
Journal of Clinical Oncology 32 (10), 1031, 2014
2632014
KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer
J Tie, L Lipton, J Desai, P Gibbs, RN Jorissen, M Christie, KJ Drummond, ...
Clinical Cancer Research 17 (5), 1122-1130, 2011
2612011
Evaluation of PIK3CA Mutation As a Predictor of Benefit From Nonsteroidal Anti-Inflammatory Drug Therapy in Colorectal Cancer
E Domingo, DN Church, O Sieber, R Ramamoorthy, Y Yanagisawa, ...
Journal of clinical oncology 31 (34), 4297-4305, 2013
2402013
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
C Oliveira, JL Westra, D Arango, M Ollikainen, E Domingo, A Ferreira, ...
Human molecular genetics 13 (19), 2303-2311, 2004
2392004
BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes
E Domingo, RC Niessen, C Oliveira, P Alhopuro, C Moutinho, E Espín, ...
Oncogene 24 (24), 3995-3998, 2005
2192005
Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning
K Sirinukunwattana, E Domingo, SD Richman, KL Redmond, A Blake, ...
Gut 70 (3), 544-554, 2021
1812021
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