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Andrew Tutt
Andrew Tutt
Professor of Oncology, Institute of Cancer Research London and Kings College London
Overená e-mailová adresa na: kcl.ac.uk
Názov
Citované v
Citované v
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
97702013
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
H Farmer, N McCabe, CJ Lord, ANJ Tutt, DA Johnson, TB Richardson, ...
Nature 434 (7035), 917-921, 2005
72022005
Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
A Goldhirsch, EP Winer, AS Coates, RD Gelber, M Piccart-Gebhart, ...
Annals of oncology 24 (9), 2206-2223, 2013
43132013
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
PC Fong, DS Boss, TA Yap, A Tutt, P Wu, M Mergui-Roelvink, P Mortimer, ...
New England Journal of Medicine 361 (2), 123-134, 2009
42982009
Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015
AS Coates, EP Winer, A Goldhirsch, RD Gelber, M Gnant, ...
Annals of oncology 26 (8), 1533-1546, 2015
22322015
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
21712016
Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial
A Tutt, M Robson, JE Garber, SM Domchek, MW Audeh, JN Weitzel, ...
The Lancet 376 (9737), 235-244, 2010
21622010
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
20582012
Hallmarks of'BRCAness' in sporadic cancers
N Turner, A Tutt, A Ashworth
Nature reviews cancer 4 (10), 814-819, 2004
19622004
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
19102012
Oral poly (ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
MW Audeh, J Carmichael, RT Penson, M Friedlander, B Powell, ...
The lancet 376 (9737), 245-251, 2010
16782010
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1671*2020
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
15502012
Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly (ADP-ribose) polymerase inhibition
N McCabe, NC Turner, CJ Lord, K Kluzek, A Białkowska, S Swift, ...
Cancer research 66 (16), 8109-8115, 2006
14762006
Triple negative tumours: a critical review
JS Reis‐Filho, ANJ Tutt
Histopathology 52 (1), 108-118, 2008
12762008
De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017
G Curigliano, HJ Burstein, EP Winer, M Gnant, P Dubsky, S Loibl, ...
Annals of Oncology 28 (8), 1700-1712, 2017
12402017
Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses in BRCA Carrier Ovarian Cancer Correlating With Platinum-Free Interval
PC Fong, TA Yap, DS Boss, CP Carden, M Mergui-Roelvink, C Gourley, ...
Journal of clinical oncology 28 (15), 2512-2519, 2010
11082010
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade
S Loi, B Haibe-Kains, C Desmedt, F Lallemand, AM Tutt, C Gillet, P Ellis, ...
Journal of clinical oncology 25 (10), 1239-1246, 2007
9442007
Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer
ANJ Tutt, JE Garber, B Kaufman, G Viale, D Fumagalli, P Rastogi, ...
New England Journal of Medicine 384 (25), 2394-2405, 2021
9372021
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ...
Nature medicine 23 (4), 517-525, 2017
9202017
Systém momentálne nemôže vykonať operáciu. Skúste to neskôr.
Články 1–20