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Patricia M. Legler
Patricia M. Legler
Overená e-mailová adresa na: nrl.navy.mil - Domovská stránka
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Citované v
Citované v
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Structures and mechanisms of Nudix hydrolases
AS Mildvan, Z Xia, HF Azurmendi, V Saraswat, PM Legler, MA Massiah, ...
Archives of biochemistry and biophysics 433 (1), 129-143, 2005
3342005
Adjustment of Codon Usage Frequencies by Codon Harmonization Improves Protein Expression and Folding
E Angov, PM Legler, RM Mease
Methods in Molecular Biology 705, 1-13, 2011
892011
Histidine affinity tags affect MSP142 structural stability and immunodominance in mice
F Khan, PM Legler, RM Mease, EH Duncan, ES Bergmann‐Leitner, ...
Biotechnology journal 7 (1), 133-147, 2012
882012
Cellular and humoral immune effector mechanisms required for sterile protection against sporozoite challenge induced with the novel malaria vaccine candidate CelTOS
ES Bergmann-Leitner, PM Legler, T Savranskaya, CF Ockenhouse, ...
Vaccine 29 (35), 5940-5949, 2011
752011
Kinetic, stereochemical, and structural effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase
TK Harris, RM Czerwinski, WH Johnson, PM Legler, C Abeygunawardana, ...
Biochemistry 38 (38), 12343-12357, 1999
721999
Evaluation of disulfide bond position to enhance the thermal stability of a highly stable single domain antibody
D Zabetakis, MA Olson, GP Anderson, PM Legler, ER Goldman
PLoS One 9 (12), e115405, 2014
592014
Effects of mutations of the active site arginine residues in 4-oxalocrotonate tautomerase on the p K a values of active site residues and on the pH dependence of catalysis
RM Czerwinski, TK Harris, WH Johnson, PM Legler, JT Stivers, ...
Biochemistry 38 (38), 12358-12366, 1999
521999
Probing the donor and acceptor substrate specificity of the γ-glutamyl transpeptidase
X Hu, PM Legler, I Khavrutskii, A Scorpio, JR Compton, KL Robertson, ...
Biochemistry 51 (6), 1199-1212, 2012
502012
Reexamination of human T cell lymphotropic virus (HTLV-I/II) prevalence
D Zucker-Franklin, BA Pancake, M Marmor, PM Legler
Proceedings of the National Academy of Sciences 94 (12), 6403-6407, 1997
411997
Structure of RiVax: a recombinant ricin vaccine
PM Legler, RN Brey, JE Smallshaw, ES Vitetta, CB Millard
Acta Crystallographica Section D: Biological Crystallography 67 (9), 826-830, 2011
402011
Three-dimensional solution structure of the cytoplasmic B domain of the mannitol transporter IIMannitol of the Escherichia coli phosphotransferase system
PM Legler, M Cai, A Peterkofsky, GM Clore
Journal of Biological Chemistry 279 (37), 39115-39121, 2004
392004
Kinetic, Mutational, and Structural Studies of the Venezuelan Equine Encephalitis Virus Nonstructural Protein 2 Cysteine Protease
X Hu, JR Compton, DH Leary, MA Olson, MS Lee, J Cheung, W Ye, ...
Biochemistry, 10.13140/RG.2.1.2883.6721, 2016
382016
Structural Characterization and Reversal of the Natural Organophosphate Resistance of a D-Type Esterase, Saccharomyces cerevisiae S-Formylglutathione …
PM Legler, D Kumaran, S Swaminathan, FW Studier, CB Millard
Biochemistry 47 (36), 9592-9601, 2008
372008
GDP-Mannose Mannosyl Hydrolase Catalyzes Nucleophilic Substitution at Carbon, Unlike All Other Nudix Hydrolases
PM Legler, MA Massiah, MJ Bessman, AS Mildvan
Biochemistry 39 (29), 8603-8608, 2000
342000
Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme
PM Legler, MA Massiah, AS Mildvan
Biochemistry 41 (35), 10834-10848, 2002
312002
Introduction of a disulfide bond leads to stabilization and crystallization of a ricin immunogen
JR Compton, PM Legler, BV Clingan, MA Olson, CB Millard
Proteins: Structure, Function, and Bioinformatics 79 (4), 1048-1060, 2011
302011
Proteolytic cleavage of host proteins by the Group IV viral proteases of Venezuelan equine encephalitis virus and Zika virus
EM Morazzani, JR Compton, DH Leary, AV Berry, X Hu, JJ Marugan, ...
Antiviral research 164, 106-122, 2019
272019
3-substituted indole inhibitors against Francisella tularensis FabI identified by structure-based virtual screening
X Hu, JR Compton, MDM AbdulHameed, CL Marchand, KL Robertson, ...
Journal of medicinal chemistry 56 (13), 5275-5287, 2013
252013
Kinetic and magnetic resonance studies of the role of metal ions in the mechanism of Escherichia coli GDP-mannose mannosyl hydrolase, an unusual nudix enzyme
PM Legler, HC Lee, J Peisach, AS Mildvan
Biochemistry 41 (14), 4655-4668, 2002
232002
The SARS-CoV-2 SSHHPS recognized by the papain-like protease
ND Reynolds, NM Aceves, JL Liu, JR Compton, DH Leary, BT Freitas, ...
ACS Infectious Diseases 7 (6), 1483-1502, 2021
212021
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Články 1–20