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Michelle Hurchla Pyles
Michelle Hurchla Pyles
Other namesMichelle Hurchla
Unknown affiliation
Verified email at wustl.edu
Title
Cited by
Cited by
Year
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
N Watanabe, M Gavrieli, JR Sedy, J Yang, F Fallarino, SK Loftin, ...
Nature immunology 4 (7), 670-679, 2003
10602003
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
JR Sedy, M Gavrieli, KG Potter, MA Hurchla, RC Lindsley, K Hildner, ...
Nature immunology 6 (1), 90-98, 2005
8072005
B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells
MA Hurchla, JR Sedy, M Gavrielli, CG Drake, TL Murphy, KM Murphy
The Journal of Immunology 174 (6), 3377-3385, 2005
2212005
The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects
MA Hurchla, A Garcia-Gomez, MC Hornick, EM Ocio, A Li, JF Blanco, ...
Leukemia 27 (2), 430-440, 2013
1352013
Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation
C Deppong, TI Juehne, M Hurchla, LD Friend, DD Shah, CM Rose, ...
The Journal of Immunology 176 (7), 3909-3913, 2006
1272006
Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation
MA Hurchla, JR Sedy, KM Murphy
The Journal of Immunology 178 (10), 6073-6082, 2007
1032007
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling
X Su, DH Floyd, A Hughes, J Xiang, JG Schneider, O Uluckan, E Heller, ...
The Journal of clinical investigation 122 (10), 3579-3592, 2012
1022012
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment
E Heller, MA Hurchla, J Xiang, X Su, S Chen, J Schneider, KS Joeng, ...
Cancer research 72 (4), 897-907, 2012
872012
Antagonizing integrin β3 increases immunosuppression in cancer
X Su, AK Esser, SR Amend, J Xiang, Y Xu, MH Ross, GC Fox, ...
Cancer research 76 (12), 3484-3495, 2016
742016
CXCR4 protein epitope mimetic antagonist POL5551 disrupts metastasis and enhances chemotherapy effect in triple-negative breast cancer
J Xiang, MA Hurchla, F Fontana, X Su, SR Amend, AK Esser, GJ Douglas, ...
Molecular cancer therapeutics 14 (11), 2473-2485, 2015
622015
Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria
B Lepenies, K Pfeffer, MA Hurchla, TL Murphy, KM Murphy, J Oetzel, ...
The Journal of Immunology 179 (6), 4093-4100, 2007
612007
Thrombospondin‐1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts
SR Amend, O Uluckan, M Hurchla, D Leib, D Veis Novack, M Silva, ...
Journal of Bone and Mineral Research 30 (1), 106-115, 2015
592015
Interferon-γ targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases
Z Xu, MA Hurchla, H Deng, O Uluškan, F Bu, A Berdy, MC Eagleton, ...
Journal of Biological Chemistry 284 (7), 4658-4666, 2009
592009
Dissection of platelet and myeloid cell defects by conditional targeting of the β3-integrin subunit
EA Morgan, JG Schneider, TE Baroni, Í Uluškan, E Heller, MA Hurchla, ...
The FASEB Journal 24 (4), 1117, 2010
562010
Very Late Antigen-4 (α4β1 Integrin) Targeted PET Imaging of Multiple Myeloma
D Soodgupta, MA Hurchla, M Jiang, A Zheleznyak, KN Weilbaecher, ...
PloS one 8 (2), e55841, 2013
432013
Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo
TA Lansdell, MA Hurchla, J Xiang, S Hovde, KN Weilbaecher, RW Henry, ...
ACS chemical biology 8 (3), 578-587, 2013
422013
Whole genome sequence of multiple myeloma-prone C57BL/KaLwRij mouse strain suggests the origin of disease involves multiple cell types
SR Amend, WC Wilson, L Chu, L Lu, P Liu, D Serie, X Su, Y Xu, D Wang, ...
PloS one 10 (5), e0127828, 2015
372015
The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice
DA Rauch, MA Hurchla, JC Harding, H Deng, LK Shea, MC Eagleton, ...
PloS one 5 (12), e15755, 2010
312010
Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa
C Stienne, R Virgen-Slane, L ElmÚn, M Veny, S Huang, J Nguyen, ...
Cell reports 38 (12), 2022
142022
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis
MA Hurchla, KN Weilbaecher
Oncoimmunology 1 (8), 1411-1413, 2012
32012
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