Jay Berzofsky
Jay Berzofsky
Chief, Vaccine Branch, CCR, NCI, NIH
Verified email at
Cited by
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The antigenic structure of proteins: a reappraisal
DC Benjamin, JA Berzofsky, IJ East, FRN Gurd, C Hannum, SJ Leach, ...
Annual review of immunology 2 (1), 67-101, 1984
Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells
C Ma, M Han, B Heinrich, Q Fu, Q Zhang, M Sandhu, D Agdashian, ...
Science 360 (6391), eaan5931, 2018
NKT cell–mediated repression of tumor immunosurveillance by IL-13 and the IL-4R–STAT6 pathway
M Terabe, S Matsui, N Noben-Trauth, H Chen, C Watson, DD Donaldson, ...
Nature immunology 1 (6), 515-520, 2000
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
R Zeng, R Spolski, SE Finkelstein, SK Oh, PE Kovanen, CS Hinrichs, ...
The Journal of experimental medicine 201 (1), 139-148, 2005
Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins
JL Cornette, KB Cease, H Margalit, JL Spouge, JA Berzofsky, C DeLisi
Journal of molecular biology 195 (3), 659-685, 1987
T-cell antigenic sites tend to be amphipathic structures.
C Delisi, JA Berzofsky
Proceedings of the National Academy of Sciences 82 (20), 7048-7052, 1985
Transforming growth factor-β production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte–mediated tumor …
M Terabe, S Matsui, JM Park, M Mamura, N Noben-Trauth, DD Donaldson, ...
The Journal of experimental medicine 198 (11), 1741-1752, 2003
Selective expansion of high-or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.
MA Alexander-Miller, GR Leggatt, JA Berzofsky
Proceedings of the National Academy of Sciences 93 (9), 4102-4107, 1996
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs
H Takahashi, T Takeshfta, B Morein, S Putney, RN Germain, JA Berzofsky
Nature 344 (6269), 873-875, 1990
Intrinsic and extrinsic factors in protein antigenic structure
JA Berzofsky
Science 229 (4717), 932-940, 1985
Prediction of immunodominant helper T cell antigenic sites from the primary sequence.
H Margalit, JL Spouge, JL Cornette, KB Cease, C Delisi, JA Berzofsky
Journal of immunology (Baltimore, Md.: 1950) 138 (7), 2213-2229, 1987
Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.
A Sher, RT Gazzinelli, IP Oswald, M Clerici, M Kullberg, EJ Pearce, ...
Immunological reviews 127, 183-204, 1992
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses
JA Hall, N Bouladoux, CM Sun, EA Wohlfert, RB Blank, Q Zhu, ME Grigg, ...
Immunity 29 (4), 637-649, 2008
Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1
M Clerici, JV Giorgi, CC Chou, VK Gudeman, JA Zack, P Gupta, HN Ho, ...
Journal of Infectious Diseases 165 (6), 1012-1019, 1992
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro
M Clerici, DR Lucey, JA Berzofsky, LA Pinto, TA Wynn, SP Blatt, MJ Dolan, ...
Science 262 (5140), 1721-1724, 1993
Strategies for designing and optimizing new generation vaccines
JA Berzofsky, JD Ahlers, IM Belyakov
Nature Reviews Immunology 1 (3), 209-219, 2001
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine …
H Takahashi, J Cohen, A Hosmalin, KB Cease, R Houghten, JL Cornette, ...
Proceedings of the National Academy of Sciences 85 (9), 3105-3109, 1988
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells
H Zhang, KS Chua, M Guimond, V Kapoor, MV Brown, TA Fleisher, ...
Nature medicine 11 (11), 1238-1243, 2005
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.
M Clerici, TA Wynn, JA Berzofsky, SP Blatt, CW Hendrix, A Sher, ...
The Journal of clinical investigation 93 (2), 768-775, 1994
Progress on new vaccine strategies for the immunotherapy and prevention of cancer
JA Berzofsky, M Terabe, SK Oh, IM Belyakov, JD Ahlers, JE Janik, ...
The Journal of clinical investigation 113 (11), 1515-1525, 2004
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