Oliver Sieber
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FunRich: An open access standalone functional enrichment and interaction network analysis tool
M Pathan, S Keerthikumar, CS Ang, L Gangoda, CYJ Quek, ...
Proteomics 15 (15), 2597-2601, 2015
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH
OM Sieber, L Lipton, M Crabtree, K Heinimann, P Fidalgo, RKS Phillips, ...
New England Journal of Medicine 348 (9), 791-799, 2003
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24. 21
I Tomlinson, E Webb, L Carvajal-Carmona, P Broderick, Z Kemp, S Spain, ...
Nature genetics 39 (8), 984-988, 2007
Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer
B Tran, S Kopetz, J Tie, P Gibbs, ZQ Jiang, CH Lieu, A Agarwal, DM Maru, ...
Cancer 117 (20), 4623-4632, 2011
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
P Broderick, L Carvajal-Carmona, AM Pittman, E Webb, K Howarth, ...
Nature genetics 39 (11), 1315-1317, 2007
Metastasis-associated gene expression changes predict poor outcomes in patients with Dukes stage B and C colorectal cancer
RN Jorissen, P Gibbs, M Christie, S Prakash, L Lipton, J Desai, D Kerr, ...
Clinical Cancer Research 15 (24), 7642-7651, 2009
Genomic instability—the engine of tumorigenesis?
OM Sieber, K Heinimann, IPM Tomlinson
Nature reviews cancer 3 (9), 701-708, 2003
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer
D Mouradov, C Sloggett, RN Jorissen, CG Love, S Li, AW Burgess, ...
Cancer research 74 (12), 3238-3247, 2014
Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution
SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ...
Cancer discovery 4 (2), 175-185, 2014
Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically
TL Putoczki, S Thiem, A Loving, RA Busuttil, NJ Wilson, PK Ziegler, ...
Cancer cell 24 (2), 257-271, 2013
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
NI Fleming, RN Jorissen, D Mouradov, M Christie, A Sakthianandeswaren, ...
Cancer research 73 (2), 725-735, 2013
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway
L Lipton, SE Halford, V Johnson, MR Novelli, A Jones, C Cummings, ...
Cancer research 63 (22), 7595-7599, 2003
Optimizing targeted therapeutic development: Analysis of a colorectal cancer patient population with the BRAFV600E mutation
J Tie, P Gibbs, L Lipton, M Christie, RN Jorissen, AW Burgess, M Croxford, ...
International journal of cancer 128 (9), 2075-2084, 2011
KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer
J Tie, L Lipton, J Desai, P Gibbs, RN Jorissen, M Christie, KJ Drummond, ...
Clinical Cancer Research 17 (5), 1122-1130, 2011
Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer
IPM Tomlinson, LG Carvajal-Carmona, SE Dobbins, A Tenesa, AM Jones, ...
PLoS genetics 7 (6), e1002105, 2011
Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer
E Domingo, DN Church, O Sieber, R Ramamoorthy, Y Yanagisawa, ...
J clin Oncol 31 (34), 4297-4305, 2013
BRAF V600E mutant colorectal cancer subtypes based on gene expression
D Barras, E Missiaglia, P Wirapati, OM Sieber, RN Jorissen, C Love, ...
Clinical Cancer Research 23 (1), 104-115, 2017
The adenomatous polyposis coli (APC) tumour suppressor–genetics, function and disease
OM Sieber, IP Tomlinson, H Lamlum
Molecular medicine today 6 (12), 462-469, 2000
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or “multiple” colorectal adenomas
OM Sieber, H Lamlum, MD Crabtree, AJ Rowan, E Barclay, L Lipton, ...
Proceedings of the National Academy of Sciences 99 (5), 2954-2958, 2002
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
D Mouradov, E Domingo, P Gibbs, RN Jorissen, S Li, PY Soo, L Lipton, ...
Official journal of the American College of Gastroenterology| ACG 108 (11 …, 2013
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