Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2 TR Lyons, J O'brien, VF Borges, MW Conklin, PJ Keely, KW Eliceiri, ... Nature medicine 17 (9), 1109-1115, 2011 | 390 | 2011 |
Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species J O'Brien, T Lyons, J Monks, MS Lucia, RS Wilson, L Hines, Y Man, ... The American journal of pathology 176 (3), 1241-1255, 2010 | 309 | 2010 |
Pregnancy and breast cancer: when they collide TR Lyons, PJ Schedin, VF Borges Journal of mammary gland biology and neoplasia 14, 87-98, 2009 | 264 | 2009 |
Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer EB Callihan, D Gao, S Jindal, TR Lyons, E Manthey, S Edgerton, ... Breast cancer research and treatment 138, 549-559, 2013 | 234 | 2013 |
XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer JJ Morton, G Bird, SB Keysar, DP Astling, TR Lyons, RT Anderson, ... Oncogene 35 (3), 290-300, 2016 | 135 | 2016 |
Cyclooxygenase-2–dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer TR Lyons, VF Borges, CB Betts, Q Guo, P Kapoor, HA Martinson, S Jindal, ... The Journal of clinical investigation 124 (9), 3901-3912, 2014 | 130 | 2014 |
Poliovirus 5′-Terminal Cloverleaf RNA Is Required in cis for VPg Uridylylation and the Initiation of Negative-Strand RNA Synthesis T Lyons, KE Murray, AW Roberts, DJ Barton Journal of Virology 75 (22), 10696-10708, 2001 | 128 | 2001 |
Collagen architecture in pregnancy-induced protection from breast cancer O Maller, KC Hansen, TR Lyons, I Acerbi, VM Weaver, R Prekeris, AC Tan, ... Journal of cell science 126 (18), 4108-4110, 2013 | 125 | 2013 |
Cancer cell CD44 mediates macrophage/monocyte-driven regulation of head and neck cancer stem cells KE Gomez, FL Wu, SB Keysar, JJ Morton, B Miller, TS Chimed, PN Le, ... Cancer research 80 (19), 4185-4198, 2020 | 123 | 2020 |
Association between postpartum breast cancer diagnosis and metastasis and the clinical features underlying risk ET Goddard, S Bassale, T Schedin, S Jindal, J Johnston, E Cabral, ... JAMA network open 2 (1), e186997-e186997, 2019 | 89 | 2019 |
Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes R Hattar, O Maller, S McDaniel, KC Hansen, KJ Hedman, TR Lyons, ... Breast Cancer Research 11, 1-16, 2009 | 79 | 2009 |
The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion A Jacob, E Linklater, BA Bayless, T Lyons, R Prekeris Journal of cell science 129 (23), 4341-4353, 2016 | 65 | 2016 |
Developmental windows of breast cancer risk provide opportunities for targeted chemoprevention HA Martinson, TR Lyons, ED Giles, VF Borges, P Schedin Experimental cell research 319 (11), 1671-1678, 2013 | 61 | 2013 |
Semaphorin 7A promotes macrophage-mediated lymphatic remodeling during postpartum mammary gland involution and in breast cancer AM Elder, BAJ Tamburini, LS Crump, SA Black, VM Wessells, PJ Schedin, ... Cancer research 78 (22), 6473-6485, 2018 | 58 | 2018 |
Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression SA Black, AC Nelson, NJ Gurule, BW Futscher, TR Lyons Oncogene 35 (39), 5170-5178, 2016 | 57 | 2016 |
Postpartum involution and cancer: an opportunity for targeted breast cancer prevention and treatments? VF Borges, TR Lyons, D Germain, P Schedin Cancer research 80 (9), 1790-1798, 2020 | 51 | 2020 |
Mammary gland involution as an immunotherapeutic target for postpartum breast cancer J Fornetti, HA Martinson, CB Betts, TR Lyons, S Jindal, Q Guo, ... Journal of mammary gland biology and neoplasia 19, 213-228, 2014 | 46 | 2014 |
AKT regulates BRCA1 stability in response to hormone signaling AC Nelson, TR Lyons, CD Young, KC Hansen, SM Anderson, JT Holt Molecular and cellular endocrinology 319 (1-2), 129-142, 2010 | 38 | 2010 |
Regulation of the Pro-apoptotic scaffolding protein POSH by Akt TR Lyons, J Thorburn, PW Ryan, A Thorburn, SM Anderson, ... Journal of Biological Chemistry 282 (30), 21987-21997, 2007 | 33 | 2007 |
Studies of postpartum mammary gland involution reveal novel pro-metastatic mechanisms TR Wallace, SE Tarullo, LS Crump, TR Lyons Journal of cancer metastasis and treatment 5, 2019 | 32 | 2019 |