| Nucleic acids in chemistry and biology GM Blackburn Royal Society of Chemistry, 2006 | 1370 | 2006 |
| Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ... Cell 145 (2), 198-211, 2011 | 339 | 2011 |
| Metal ions play a passive role in the hairpin ribozyme catalysed reaction KJ Young, F Gill, JA Grasby Nucleic acids research 25 (19), 3760-3760, 1997 | 230 | 1997 |
| Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity SE Lee, A Sidorov, T Gourlain, N Mignet, SJ Thorpe, JA Brazier, ... Nucleic Acids Research 29 (7), 1565-1573, 2001 | 172 | 2001 |
| Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA JA Grasby, K Mersmann, M Singh, MJ Gait Biochemistry 34 (12), 4068-4076, 1995 | 156 | 1995 |
| Hydrogen-bonding contacts in the major groove are required for human immunodeficiency virus type-1 tat protein recognition of TAR RNA F Hamy, U Asseline, J Grasby, S Iwai, C Pritchard, G Slim, PJG Butler, ... Journal of molecular biology 230 (1), 111-123, 1993 | 153 | 1993 |
| Enhancing the catalytic repertoire of nucleic acids. II. Simultaneous incorporation of amino and imidazolyl functionalities by two modified triphosphates during PCR T Gourlain, A Sidorov, N Mignet, SJ Thorpe, SE Lee, JA Grasby, ... Nucleic Acids Research 29 (9), 1898-1905, 2001 | 143 | 2001 |
| Sequence‐specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities AV Sidorov, JA Grasby, DM Williams Nucleic acids research 32 (4), 1591-1601, 2004 | 141 | 2004 |
| Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability SE Tsutakawa, MJ Thompson, AS Arvai, AJ Neil, SJ Shaw, SI Algasaier, ... Nature communications 8 (1), 15855, 2017 | 115 | 2017 |
| Methylphosphonate mapping of phosphate contacts critical for RNA recognition by the human immunodeficiency virus tat and rev proteins CE Pritchard, JA Grasby, F Hamy, AM Zacharek, M Singh, J Karn, MJ Gait Nucleic acids research 22 (13), 2592-2600, 1994 | 110 | 1994 |
| Stereochemical outcome of the hydrolysis reaction catalyzed by the EcoRV restriction endonuclease JA Grasby, BA Connolly Biochemistry 31 (34), 7855-7861, 1992 | 102 | 1992 |
| Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases JA Grasby, LD Finger, SE Tsutakawa, JM Atack, JA Tainer Trends in biochemical sciences 37 (2), 74-84, 2012 | 81 | 2012 |
| The 3′-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis LD Finger, MS Blanchard, CA Theimer, B Sengerová, P Singh, V Chavez, ... Journal of Biological Chemistry 284 (33), 22184-22194, 2009 | 77 | 2009 |
| Influence of the Phosphate Backbone on the Recognition and Hydrolysis of DNA by the EcoRV Restriction Endonuclease: A STUDY USING OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATES (∗) H Thorogood, JA Grasby, BA Connolly Journal of Biological Chemistry 271 (15), 8855-8862, 1996 | 76 | 1996 |
| Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site JC Exell, MJ Thompson, LD Finger, SJ Shaw, J Debreczeni, TA Ward, ... Nature chemical biology 12 (10), 815-821, 2016 | 72 | 2016 |
| The wonders of flap endonucleases: structure, function, mechanism and regulation LD Finger, JM Atack, S Tsutakawa, S Classen, J Tainer, J Grasby, B Shen The eukaryotic replisome: a guide to protein structure and function, 301-326, 2012 | 68 | 2012 |
| Substrate recognition and catalysis by flap endonucleases and related enzymes CG Tomlinson, JM Atack, B Chapados, JA Tainer, JA Grasby Biochemical Society Transactions 38 (2), 433-437, 2010 | 68 | 2010 |
| The RuvABC resolvasome: Quantitative analysis of RuvA and RuvC assembly on junction DNA MJ Dickman, SM Ingleston, SE Sedelnikova, JB Rafferty, RG Lloyd, ... European journal of biochemistry 269 (22), 5492-5501, 2002 | 64 | 2002 |
| The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage JA Grasby, P Jonathan, G Butler, JG Michael Nucleic acids research 21 (19), 4444-4450, 1993 | 64 | 1993 |
| Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease MR Tock, E Frary, JR Sayers, JA Grasby The EMBO journal, 2003 | 59 | 2003 |
John M AtackInstitute for Glycomics, Griffith UniversityVerified email at griffith.edu.au
