| Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy J Newton, S Lima, M Maceyka, S Spiegel Experimental cell research 333 (2), 195-200, 2015 | 256 | 2015 |
| Dual molecular signals mediate the bacterial response to outer-membrane stress S Lima, MS Guo, R Chaba, CA Gross, RT Sauer Science 340 (6134), 837-841, 2013 | 198 | 2013 |
| A redox-active FKBP-type immunophilin functions in accumulation of the photosystem II supercomplex in Arabidopsis thaliana A Lima, S Lima, JH Wong, RS Phillips, BB Buchanan, S Luan Proceedings of the National Academy of Sciences 103 (33), 12631-12636, 2006 | 133 | 2006 |
| Sphingosine and sphingosine kinase 1 involvement in endocytic membrane trafficking S Lima, S Milstien, S Spiegel Journal of Biological Chemistry 292 (8), 3074-3088, 2017 | 74 | 2017 |
| ABCC1-exported sphingosine-1-phosphate, produced by sphingosine kinase 1, shortens survival of mice and patients with breast cancer A Yamada, M Nagahashi, T Aoyagi, WC Huang, S Lima, NC Hait, A Maiti, ... Molecular Cancer Research 16 (6), 1059-1070, 2018 | 63 | 2018 |
| Crystal Structure of Homo sapiens Kynureninase, S Lima, R Khristoforov, C Momany, RS Phillips Biochemistry 46 (10), 2735-2744, 2007 | 55 | 2007 |
| Crystal Structure of the Homo sapiens Kynureninase-3-Hydroxyhippuric Acid Inhibitor Complex: Insights into the Molecular Basis Of Kynureninase Substrate … S Lima, S Kumar, V Gawandi, C Momany, RS Phillips Journal of medicinal chemistry 52 (2), 389-396, 2009 | 54 | 2009 |
| TP53 is required for BECN1-and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition S Lima, K Takabe, J Newton, K Saurabh, MM Young, AM Leopoldino, ... Autophagy 14 (6), 942-957, 2018 | 46 | 2018 |
| Three-Dimensional Structure of Kynureninase from Pseudomonas fluorescens, C Momany, V Levdikov, L Blagova, S Lima, RS Phillips Biochemistry 43 (5), 1193-1203, 2004 | 41 | 2004 |
| Differential radiation sensitivity in p53 wild-type and p53-deficient tumor cells associated with senescence but not apoptosis or (nonprotective) autophagy J Xu, NH Patel, T Saleh, EK Cudjoe Jr, M Alotaibi, Y Wu, S Lima, ... Radiation research 190 (5), 538-557, 2018 | 36 | 2018 |
| An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors M Vettorazzi, E Angelina, S Lima, T Gonec, J Otevrel, P Marvanova, ... European journal of medicinal chemistry 139, 461-481, 2017 | 29 | 2017 |
| Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells NH Patel, J Xu, T Saleh, Y Wu, S Lima, DA Gewirtz Biochemical pharmacology 175, 113896, 2020 | 27 | 2020 |
| Structure of the first sphingosine 1-phosphate receptor AL Parrill, S Lima, S Spiegel Science signaling 5 (225), pe23-pe23, 2012 | 27 | 2012 |
| A real-time high-throughput fluorescence assay for sphingosine kinases S Lima, S Milstien, S Spiegel Journal of Lipid Research 55 (7), 1525-1530, 2014 | 26 | 2014 |
| The crystal structure of the Pseudomonas dacunhae aspartate-β-decarboxylase dodecamer reveals an unknown oligomeric assembly for a pyridoxal-5′-phosphate-dependent enzyme S Lima, B Sundararaju, C Huang, R Khristoforov, C Momany, RS Phillips Journal of molecular biology 388 (1), 98-108, 2009 | 26 | 2009 |
| Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation J Newton, END Palladino, C Weigel, M Maceyka, MH Gräler, CE Senkal, ... Journal of Biological Chemistry 295 (27), 9121-9133, 2020 | 22 | 2020 |
| Design of new quinolin-2-one-pyrimidine hybrids as sphingosine kinases inhibitors M Vettorazzi, D Insuasty, S Lima, L Gutiérrez, M Nogueras, A Marchal, ... Bioorganic chemistry 94, 103414, 2020 | 21 | 2020 |
| Insights into the Mechanism of Pseudomonas dacunhae Aspartate β-Decarboxylase from Rapid-Scanning Stopped-Flow Kinetics RS Phillips, S Lima, R Khristoforov, B Sudararaju Biochemistry 49 (24), 5066-5073, 2010 | 15 | 2010 |
| Reaction of Pseudomonas fluorescens kynureninase with β-benzoyl-L-alanine: Detection of a new reaction intermediate and a change in rate-determining step VB Gawandi, D Liskey, S Lima, RS Phillips Biochemistry 43 (11), 3230-3237, 2004 | 14 | 2004 |
| Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching EY Kim, JL Sturgill, NC Hait, D Avni, EC Valencia, M Maceyka, S Lima, ... The FASEB Journal 28 (10), 4347, 2014 | 12 | 2014 |
