Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq GPNJ Jun Chen*, Shengbao Suo*, Patrick PL Tam, Jing-Dong J Han Nature Protocols 12, 566–580, 2017 | 255 | 2017 |
Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-gastrula Mouse Embryo * Guangdun Peng*,Shengbao Suo*, Jun Chen*, Weiyang Chen, Chang Liu, Fang Yu ... Developmental Cell 36, 681-687, 2016 | 231 | 2016 |
Molecular architecture of lineage allocation and tissue organization in early mouse embryo G Peng, S Suo, G Cui, F Yu, R Wang, J Chen, S Chen, Z Liu, G Chen, ... Nature 572 (7770), 528-532, 2019 | 183 | 2019 |
The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways Q Zhu, L Song, G Peng, N Sun, J Chen, T Zhang, N Sheng, W Tang, ... Elife 3, e02224, 2014 | 86 | 2014 |
AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning Y Qiao, Y Zhu, N Sheng, J Chen, R Tao, Q Zhu, T Zhang, C Qian, N Jing Cell research 22 (11), 1546-1561, 2012 | 42 | 2012 |
HOTAIRM1, an enhancer lncRNA, promotes glioma proliferation by regulating long-range chromatin interactions within HOXA cluster genes T Shi, D Guo, H Xu, G Su, J Chen, Z Zhao, J Shi, M Wedemeyer, ... Molecular biology reports 47, 2723-2733, 2020 | 33 | 2020 |
Silencing of developmental genes by H3K27me3 and DNA methylation reflects the discrepant plasticity of embryonic and extraembryonic lineages X Yang, B Hu, Y Hou, Y Qiao, R Wang, Y Chen, Y Qian, S Feng, J Chen, ... Cell Research 28 (5), 593-596, 2018 | 33 | 2018 |
Enhancer reprogramming within pre-existing topologically associated domains promotes TGFβ-induced epithelial-to-mesenchymal transition and cancer metastasis Y Qiao, Z Wang, F Tan, J Chen, J Lin, J Yang, H Li, X Wang, A Sali, ... Molecular Therapy, 2020 | 30 | 2020 |
Ectodermal progenitors derived from epiblast stem cells by inhibition of Nodal signaling L Li, L Song, C Liu, J Chen, G Peng, R Wang, P Liu, K Tang, J Rossant, ... Journal of molecular cell biology 7 (5), 455-465, 2015 | 30 | 2015 |
Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate P Liu, X Dou, C Liu, L Wang, C Xing, G Peng, J Chen, F Yu, Y Qiao, ... Nature communications 6 (1), 6830, 2015 | 30 | 2015 |
A HOTAIR regulatory element modulates glioma cell sensitivity to temozolomide through long-range regulation of multiple target genes L Zhang, A He, B Chen, J Bi, J Chen, D Guo, Y Qian, W Wang, T Shi, ... Genome research 30 (2), 155-163, 2020 | 28 | 2020 |
The dual histone demethylase KDM7A promotes neural induction in early chick embryos C Huang, J Chen, T Zhang, Q Zhu, Y Xiang, CD Chen, N Jing Developmental Dynamics 239 (12), 3350-3357, 2010 | 25 | 2010 |
Opposing roles of acetylation and phosphorylation in LIFR-dependent self-renewal growth signaling in mouse embryonic stem cells X Wang, Y Qiao, MM Xiao, L Wang, J Chen, W Lv, L Xu, Y Li, Y Wang, ... Cell reports 18 (4), 933-946, 2017 | 21 | 2017 |
Suppressing nodal signaling activity predisposes ectodermal differentiation of epiblast stem cells C Liu, R Wang, Z He, P Osteil, E Wilkie, X Yang, J Chen, G Cui, W Guo, ... Stem Cell Reports 11 (1), 43-57, 2018 | 20 | 2018 |
Dynamic heterogeneity of brachyury in mouse epiblast stem cells mediates distinct response to extrinsic Bone Morphogenetic Protein (BMP) signaling L Song, J Chen, G Peng, K Tang, N Jing Journal of Biological Chemistry 291 (29), 15212-15225, 2016 | 18 | 2016 |
The roles of mesenchymal stem cell-derived exosomes in diabetes mellitus and its related complications M Yang, J Chen, L Chen Frontiers in Endocrinology 13, 1027686, 2022 | 15 | 2022 |
A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation G Su, D Guo, J Chen, M Liu, J Zheng, W Wang, X Zhao, Q Yin, L Zhang, ... Nucleic acids research 47 (13), 6737-6752, 2019 | 15 | 2019 |
Abnormal Paraventricular Nucleus of Hypothalamus and Growth Retardation Associated with Loss of Nuclear Receptor Gene COUP-TFII S Feng, C Xing, T Shen, Y Qiao, R Wang, J Chen, J Liao, Z Lu, X Yang, ... Scientific reports 7 (1), 5282, 2017 | 12 | 2017 |
CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA G Su, W Wang, J Chen, M Liu, J Zheng, D Guo, J Bi, Z Zhao, J Shi, ... Journal of Biological Chemistry 296, 2021 | 10 | 2021 |
Genome-wide ChIP-seq and RNA-seq analyses of Pou3f1 during mouse pluripotent stem cell neural fate commitment L Song, N Sun, G Peng, J Chen, JDJ Han, N Jing Genomics data 5, 375-377, 2015 | 9 | 2015 |