Jean-Christophe Pignon
Jean-Christophe Pignon
Principal Scientist
Overená e-mailová adresa na:
Citované v
Citované v
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
B Li, E Severson, JC Pignon, H Zhao, T Li, J Novak, P Jiang, H Shen, ...
Genome biology 17, 1-16, 2016
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma
DA Braun, Y Hou, Z Bakouny, M Ficial, M Sant’Angelo, J Forman, ...
Nature medicine 26 (6), 909-918, 2020
Landscape of tumor-infiltrating T cell repertoire of human cancers
B Li, T Li, JC Pignon, B Wang, J Wang, SA Shukla, R Dou, Q Chen, ...
Nature genetics 48 (7), 725-732, 2016
p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia
JC Pignon, C Grisanzio, Y Geng, J Song, RA Shivdasani, S Signoretti
Proceedings of the National Academy of Sciences 110 (20), 8105-8110, 2013
Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic renal cell carcinoma
DJ Kwiatkowski, TK Choueiri, AP Fay, BI Rini, AR Thorner, G De Velasco, ...
Clinical Cancer Research 22 (10), 2445-2452, 2016
Efficacy and safety of nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma
NM Tannir, S Signoretti, TK Choueiri, DF McDermott, RJ Motzer, A Flaifel, ...
Clinical Cancer Research 27 (1), 78-86, 2021
irRECIST for the evaluation of candidate biomarkers of response to nivolumab in metastatic clear cell renal cell carcinoma: analysis of a phase II prospective clinical trial
JC Pignon, O Jegede, SA Shukla, DA Braun, CE Horak, M Wind-Rotolo, ...
Clinical Cancer Research 25 (7), 2174-2184, 2019
Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines
JC Pignon, B Koopmansch, G Nolens, L Delacroix, D Waltregny, ...
Cancer research 69 (7), 2941-2949, 2009
KIR3DL3 is an inhibitory receptor for HHLA2 that mediates an alternative immunoinhibitory pathway to PD1
RS Bhatt, A Berjis, JC Konge, KM Mahoney, AN Klee, SS Freeman, ...
Cancer immunology research 9 (2), 156-169, 2021
Expression of T-cell exhaustion molecules and human endogenous retroviruses as predictive biomarkers for response to nivolumab in metastatic clear cell renal cell carcinoma
M Ficial, OA Jegede, M Sant'Angelo, Y Hou, A Flaifel, JC Pignon, ...
Clinical Cancer Research 27 (5), 1371-1380, 2021
Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2overexpression in breast cancer cell lines
G Nolens, JC Pignon, B Koopmansch, B Elmoualij, W Zorzi, E De Pauw, ...
Breast Cancer Research 11, 1-11, 2009
Differential expression of c-Met between primary and metastatic sites in clear-cell renal cell carcinoma and its association with PD-L1 expression
AKA Lalani, KP Gray, L Albiges, M Callea, JC Pignon, S Pal, M Gupta, ...
Oncotarget 8 (61), 103428, 2017
Young investigator challenge: application of cytologic techniques to circulating tumor cell specimens: detecting activation of the oncogenic transcription factor STAT3
AC Lowe, JC Pignon, I Carvo, MG Drage, NM Constantine, N Jones, ...
Cancer Cytopathology 123 (12), 696-706, 2015
p63+ ureteric bud tip cells are progenitors of intercalated cells
SS El-Dahr, Y Li, J Liu, E Gutierrez, KS Hering-Smith, S Signoretti, ...
JCI insight 2 (9), 2017
ΔNp63 (p40) expression in prostatic adenocarcinoma with diffuse p63 positivity
K Uchida, H Ross, T Lotan, JC Pignon, S Signoretti, JI Epstein, PB Illei
Human pathology 46 (3), 384-389, 2015
Transcriptomic correlates of tumor cell PD-L1 expression and response to nivolumab monotherapy in metastatic clear cell renal cell carcinoma
T Denize, Y Hou, JC Pignon, E Walton, DJ West, GJ Freeman, DA Braun, ...
Clinical Cancer Research 28 (18), 4045-4055, 2022
Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma
L Hamieh, TK Choueiri, B Ogórek, D Khabibullin, D Rosebrock, D Livitz, ...
PLoS genetics 14 (9), e1007679, 2018
Impact of immune checkpoint protein expression in tumor cells and tumor infiltrating CD8+ T cells on clinical benefit from PD-1 blockade in metastatic clear cell …
JC Pignon, O Jegede, KM Mahoney, RB Moreira, J Novak, H Conen, ...
Journal of Clinical Oncology 35 (6_suppl), 477-477, 2017
Evaluation of predictive biomarkers for nivolumab in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) from the CheckMate-025 (CM-025) trial.
M Ficial, O Jegede, M Sant'Angelo, S Moreno, DA Braun, M Wind-Rotolo, ...
Journal of Clinical Oncology 38 (15_suppl), 5023-5023, 2020
Association of human endogenous retrovirus (hERV) expression with clinical efficacy of PD-1 blockade in metastatic clear cell renal cell carcinoma (mccRCC).
JC Pignon, O Jegede, SA Shukla, DA Braun, C Horak, M Wind-Rotolo, ...
Journal of Clinical Oncology 37 (15_suppl), 4568-4568, 2019
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Články 1–20