Margaret Ackerman
Margaret Ackerman
Professor of Engineering, Thayer School of Engineering, Dartmouth College
Verified email at - Homepage
Cited by
Cited by
A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
ME Ackerman, B Moldt, RT Wyatt, AS Dugast, E McAndrew, S Tsoukas, ...
Journal of immunological methods 366 (1-2), 8-19, 2011
Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines
AW Chung, M Ghebremichael, H Robinson, E Brown, I Choi, S Lane, ...
Science translational medicine 6 (228), 228ra38-228ra38, 2014
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity
ME Ackerman, M Crispin, X Yu, K Baruah, AW Boesch, DJ Harvey, ...
The Journal of clinical investigation 123 (5), 2183-2192, 2013
Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology
AW Chung, MP Kumar, KB Arnold, WH Yu, MK Schoen, LJ Dunphy, ...
Cell 163 (4), 988-998, 2015
Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys
DH Barouch, G Alter, T Broge, C Linde, ME Ackerman, EP Brown, ...
Science 349 (6245), 320-324, 2015
Polyfunctional HIV-specific antibody responses are associated with spontaneous HIV control
ME Ackerman, A Mikhailova, EP Brown, KG Dowell, BD Walker, ...
PLoS pathogens 12 (1), e1005315, 2016
High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples
EP Brown, AF Licht, AS Dugast, I Choi, C Bailey-Kellogg, G Alter, ...
Journal of immunological methods 386 (1-2), 117-123, 2012
Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition
M Vaccari, SN Gordon, S Fourati, L Schifanella, NPM Liyanage, ...
Nature medicine 22 (7), 762-770, 2016
Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles
EP Brown, KG Dowell, AW Boesch, E Normandin, AE Mahan, T Chu, ...
Journal of immunological methods 443, 33-44, 2017
Protein-protein fusion catalyzed by sortase A
DA Levary, R Parthasarathy, ET Boder, ME Ackerman
PloS one 6 (4), e18342, 2011
A modular IgG-scFv bispecific antibody topology
KD Orcutt, ME Ackerman, M Cieslewicz, E Quiroz, AL Slusarczyk, ...
Protein Engineering, Design & Selection 23 (4), 221-228, 2010
Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge
T Bradley, J Pollara, S Santra, N Vandergrift, S Pittala, C Bailey-Kellogg, ...
Nature communications 8 (1), 15711, 2017
Stability and CDR composition biases enrich binder functionality landscapes
BJ Hackel, ME Ackerman, SW Howland, KD Wittrup
Journal of molecular biology 401 (1), 84-96, 2010
Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV
ME Ackerman, J Das, S Pittala, T Broge, C Linde, TJ Suscovich, EP Brown, ...
Nature medicine 24 (10), 1590-1598, 2018
Identification of antibody glycosylation structures that predict monoclonal antibody Fc-effector function
AW Chung, M Crispin, L Pritchard, H Robinson, MK Gorny, X Yu, ...
AIDS (London, England) 28 (17), 2523, 2014
Effect of antigen turnover rate and expression level on antibody penetration into tumor spheroids
ME Ackerman, D Pawlowski, KD Wittrup
Molecular cancer therapeutics 7 (7), 2233-2240, 2008
Enhanced phagocytic activity of HIV-specific antibodies correlates with natural production of immunoglobulins with skewed affinity for FcγR2a and FcγR2b
ME Ackerman, AS Dugast, EG McAndrew, S Tsoukas, AF Licht, DJ Irvine, ...
Journal of virology 87 (10), 5468-5476, 2013
Highly avid magnetic bead capture: an efficient selection method for de novo protein engineering utilizing yeast surface display
M Ackerman, D Levary, G Tobon, B Hackel, KD Orcutt, KD Wittrup
Biotechnology progress 25 (3), 774-783, 2009
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
M Bonsignori, K Wiehe, SK Grimm, R Lynch, G Yang, DM Kozink, F Perrin, ...
The Journal of clinical investigation 124 (4), 1835-1843, 2014
A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis
AE Mahan, J Tedesco, K Dionne, K Baruah, HD Cheng, PL De Jager, ...
Journal of immunological methods 417, 34-44, 2015
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